Anal Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Surgery in Treating Patients With Early Stage Anal Canal or Perianal Cancer and HIV Infection [Phase 2]
Phase 2 clinical trial evaluating surgery for early-stage anal canal cancer or perianal cancer in HIV-infected patients; the study has compl…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer [Phase 2]
Clinical Trial Update describes a Phase 2 study evaluating a therapy adapted for high-risk and low-risk HIV-associated anal cancer, with the…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas [Phase 1]
Phase 1 study evaluating safety, efficacy, and pharmacokinetics of EVOLVE104 in patients with advanced urothelial cancer and squamous cell c…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients [Phase 3]
This entry describes a Phase 3 clinical trial evaluating carboplatin and paclitaxel with or without nivolumab in metastatic or unresectable …
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Atezolizumab and Bevacizumab in Treating Patients With Rare Solid Tumors [Phase 2]
A Phase 2 trial investigates the combination of atezolizumab and bevacizumab in several rare solid tumors, with the study currently not recr…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: MR-Adaptive Radiation Therapy for Anal Cancer With EScalated-Treatment in a Risk-Optimized Approach [Phase 2]
A Phase 2 clinical trial evaluating MR-Adaptive Radiation Therapy with escalated treatment in a risk-optimized approach for anal squamous ce…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: HPV ctDNA Response-Adapted Chemoradiation +/- Retifanlimab Treatment in Advanced-Stage Anal Cancer [Phase 2]
A Phase 2 clinical trial is evaluating HPV DNA–guided chemoradiation with or without the PD-1 inhibitor retifanlimab for advanced anal cance…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Adaptive Radiation in Anal Cancer [NA]
A clinical trial investigating adaptive radiation for anal squamous cell carcinoma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Anal High-risk HPV, HSIL, and Microbiome Among Hispanic Peoples Living With HIV (PLWH)
Completed clinical trial evaluating high-risk HPV, high-grade squamous intraepithelial lesions (HSIL), and microbiome in Hispanic people liv…
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Phase Ib/II of TG4001 and Avelumab in HPV16 Positive R/M Cancers [Phase 1, Phase 2]
This update reports results from a Phase Ib/II study of TG4001 in combination with Avelumab in HPV16-positive recurrent/metastatic cancers, …
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid Tumors [Phase 1]
Phase 1 basket trial evaluating customized autologous TCR-T cell therapies across multiple locally advanced or metastatic solid tumors, spon…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Screening Strategies Among High-risk Populations for Anal Cancer [NA]
This clinical trial update reports a study evaluating screening strategies for high-risk populations to detect anal cancer, including HPV-re…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Identification of the Pathogenetic Mechanisms Underlying Squamous Cell Carcinomas
A clinical trial focused on identifying the pathogenetic mechanisms underlying squamous cell carcinomas of the head and neck and anus; curre…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Screening for Anal Cancer in Women With High-grade Vulvar Dysplasia or Vulvar Cancer. [NA]
Clinical trial investigating screening for anal cancer in women with high-grade vulvar dysplasia or vulvar cancer; currently recruiting.
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: Proton Versus Photon Therapy in Anal Squamous Cell Carcinoma [NA]
A clinical trial at Umeå University is currently recruiting to compare proton therapy versus photon therapy for anal squamous cell carcinoma…
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: A Global Record of Patients With Anal Squamous Cell Carcinoma With and Without HIV Infection
A global registry study by the Latin American Cooperative Oncology Group collecting data on patients with anal squamous cell carcinoma, with…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: High Resolution Anuscopy Study
A status update indicates that the High Resolution Anuscopy study is currently recruiting, investigating its use in anal squamous cell carci…
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CLINICAL_TRIALS trial_result · 2024-12-03Clinical Trial Update: PD-1 Blockade Combined With Chemotherapy Followed by Concurrent Immunoradiotherapy for Locally Advanced SCCA Patients [Phase 2]
A Phase 2 trial evaluating PD-1 blockade with chemotherapy followed by concurrent immunoradiotherapy in locally advanced anal canal cancer a…
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CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: Phase 1/2 Study of Autologous SCG142 TCR T Cells in Patients With HPV16/52-positive Carcinoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating autologous SCG142 TCR T cells for HPV16/52-positive squamous cell carcinomas across multiple HPV-related sites; c…
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: Cisplatin and Fluorouracil Compared With Carboplatin and Paclitaxel in Treating Patients With Inoperable Locally Recurrent or Metastatic Anal Cancer [Phase 2]
Phase 2 trial comparing cisplatin/fluorouracil versus carboplatin/paclitaxel in patients with inoperable locally recurrent or metastatic ana…
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CLINICAL_TRIALS trial_result · 2022-05-16Clinical Trial Update: Chemoradiotherapy Combined With or Without PD-1 Blockade in Anal Canal Squamous Carcinoma Patients [Phase 3]
Phase 3 trial evaluating chemoradiotherapy with or without PD-1 blockade for anal canal squamous carcinoma; status currently unknown.
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CLINICAL_TRIALS trial_result · 2021-02-09Clinical Trial Update: Efficacy Study of Chemoradiotherapy With or Without Paclitaxel in Squamous-cell Anal Carcinoma Patients [Phase 3]
Phase 3 trial updating efficacy of chemoradiotherapy with or without paclitaxel in squamous-cell anal carcinoma is ongoing or not yet determ…
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CLINICAL_TRIALS trial_result · 2018-06-06Clinical Trial Update: ART: Anal Squamous Cell Carcinoma: Investigation of Functional Imaging During chemoRadioTherapy
A completed University of Oxford study investigating functional imaging during chemoradiotherapy for anal squamous cell carcinoma (anal canc…
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CLINICAL_TRIALS trial_result · 2018-05-16Clinical Trial Update: Vectibix for the Treatment of Anal Cancer [Phase 2]
Phase 2 clinical trial update showing completion of Vectibix (panitumumab) for anal squamous cell carcinoma.
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CLINICAL_TRIALS trial_result · 2017-06-26Clinical Trial Update: Oral Rigosertib for Squamous Cell Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating oral rigosertib for various squamous cell carcinomas has completed.