Anal Fistula
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Evaluating an rhPDGF-BB-enhanced Collagen Plug for Perianal Fistula Healing [Phase 2]
A Phase 2 clinical trial is evaluating an rhPDGF-BB-enhanced collagen plug for healing complex perianal fistulas; the study status is ACTIVE…
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CLINICAL_TRIALS trial_result · 2025-08-03Clinical Trial Update: The Modified Clipped-LIFT Procedure for High Transsphincteric or Suprasphincteric Fistula [NA]
A clinical trial evaluating the Modified Clipped-LIFT Procedure for high transsphincteric or suprasphincteric anal fistulas has completed.
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CLINICAL_TRIALS trial_result · 2025-05-16Clinical Trial Update: Randomized Control Trial of Micronized Purified Flavonoid Fraction for Post Operative Treatment in Anal Fistula Surgery [Phase 4]
A Phase 4 randomized controlled trial evaluated micronized purified flavonoid fraction as postoperative treatment after anal fistula surgery…
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: Platelet- Rich Plasma Injection [NA]
A Mansoura University-sponsored clinical trial evaluating platelet-rich plasma injections has completed. The study targeted wound healing an…
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: Treatment of Ano-perineal Fistulas Resistant to Surgical Treatment with a Gel and Plug of Wharton's Jelly [Phase 1]
A Phase 1 trial evaluating a Wharton's jelly gel and plug for anal fistulas resistant to surgical treatment has completed. The study investi…
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CLINICAL_TRIALS trial_result · 2022-03-02Clinical Trial Update: Ligation of Intersphincteric Fistula Tract Versus Rectal Advancement Flap in the Treatment of Complex Anal Fistula [Phase 3]
Phase 3 trial update comparing ligation of intersphincteric fistula tract versus rectal advancement flap for complex anal fistula.
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CLINICAL_TRIALS trial_result · 2019-04-12Clinical Trial Update: Study to Assess the Safety and Efficacy of Expanded Allogenic Adipose-derived Stem Cells (eASCs) (Cx601), for Treatment of Complex Perianal Fistulas in Perianal Crohn's Disease. [Phase 1, Phase 2]
Clinical trial update for expanded allogenic adipose-derived stem cells (Cx601) in complex perianal fistulas associated with Crohn's disease…
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CLINICAL_TRIALS trial_result · 2019-04-12Clinical Trial Update: Efficacy and Safety of Adipose Stem Cells to Treat Complex Perianal Fistulas Not Associated to Crohn´s Disease [Phase 3]
Phase 3 trial update assessing adipose stem cells for treating complex perianal fistulas not associated with Crohn's disease; study complete…
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CLINICAL_TRIALS trial_result · 2018-04-30Clinical Trial Update: Ultrasound Guided Caudal Block for Benign Anal Surgery [NA]
A completed clinical trial evaluating ultrasound-guided caudal block for benign anorectal surgery, including conditions such as anal fissure…
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CLINICAL_TRIALS trial_result · 2018-04-19Clinical Trial Update: Clinical Trial to Evaluate the Efficacy and Safety of Stem Cells [Phase 3]
Clinical trial update indicates the Phase 3 study evaluating stem cell therapy for anal fistula has been completed. The sponsor is Instituto…
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Randomized Trial on the Effect of Topical Phenytoin on Healing After Fistulotomy [NA]
A randomized trial evaluating whether topical phenytoin improves healing after fistulotomy.
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CLINICAL_TRIALS trial_result · 2017-03-17Clinical Trial Update: Treatment of Perirectal Fistula With Cutting Seton vs. Collagen Plug [Phase 3]
Phase 3 trial comparing cutting seton versus collagen plug for anal fistula has completed.
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CLINICAL_TRIALS trial_result · 2017-01-13Clinical Trial Update: Study of GORE® BIO-A® Fistula Plug for Use in Anal Fistula Repair
The trial evaluating the GORE BIO-A Fistula Plug for anal fistula repair was terminated, with results posted on January 13, 2017.
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CLINICAL_TRIALS trial_result · 2016-11-15Clinical Trial Update: Efficacy and Safety of CLIFE1 Gel in Benign Anorectal Surgery [Phase 4]
Phase 4 trial assessing the efficacy and safety of CLIFE1 Gel in benign anorectal surgery has completed. The study evaluated CLIFE1 Gel for …
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CLINICAL_TRIALS trial_result · 2015-09-22Clinical Trial Update: Therapeutic Management of Complex Anal Fistulas by Installing a Closure Clip: Multicentre Randomized Controlled Trial [Phase 2, Phase 3]
Multicenter randomized controlled trial protocol (Phase 2/3) evaluating a closure clip for complex anal fistulas; current status is unknown.
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CLINICAL_TRIALS trial_result · 2015-05-28Clinical Trial Update: A Prospective European Post-Market Clinical Evaluation of the CuraSeal Percutaneous Intraluminal Closure System for Anorectal Fistulas [Phase 2]
Phase 2 prospective European post-market clinical evaluation of the CuraSeal Percutaneous Intraluminal Closure System for anorectal fistulas…
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CLINICAL_TRIALS trial_result · 2015-02-11Clinical Trial Update: Surgisis Anal Fistula Plug Study: An Experience in Saudi Arabia
Completed clinical trial of the Surgisis Anal Fistula Plug for treating anal fistula, conducted in Saudi Arabia.
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CLINICAL_TRIALS trial_result · 2015-02-11Clinical Trial Update: Ligation of the Intersphincteric Fistula Tract (LIFT) + Biodesign for Anal Fistula
A completed clinical trial update on the Ligation of the Intersphincteric Fistula Tract (LIFT) with Biodesign for anal fistula.
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CLINICAL_TRIALS trial_result · 2014-10-29Clinical Trial Update: A Randomized Clinical Trial Comparing Surgisis AFP to Advancement Flap for the Repair of Anal Fistulas [NA]
A randomized trial compared the Surgisis AFP graft to an advancement flap for repairing anal fistulas, with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-02-13Clinical Trial Update: Anal Fistula Plug for High-type Anal Fistulae [NA]
A clinical trial evaluating an anal fistula plug for high-type anal fistulae has been terminated.
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CLINICAL_TRIALS trial_result · 2013-08-28Clinical Trial Update: Effectiveness of Silver Nitrate Solution in the Treatment of Anal Fistula
This clinical trial examines the effectiveness of silver nitrate solution for treating anal fistula; the current status is unknown.
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CLINICAL_TRIALS trial_result · 2013-05-17Clinical Trial Update: Success Rate, Continence, and Quality of Life With a Bioprosthetic Plug for Treating Complex Anal Fistula [Phase 2]
This Phase 2 trial reports on the use of a bioprosthetic plug to treat complex anal fistula, focusing on healing, continence, and quality of…
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CLINICAL_TRIALS trial_result · 2011-08-17Clinical Trial Update: Treatment of Crohn's Fistula Using a Porcine Intestine Submucosa Graft [NA]
A trial evaluating a porcine intestine submucosa graft for Crohn's disease-related anal fistula was terminated, with results posted in 2011.
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CLINICAL_TRIALS trial_result · 2010-01-06Clinical Trial Update: Treatment of Anal Fistulas Advancement Flap [NA]
The Mansoura University trial evaluating advancement flap treatment for anal fistula has completed.
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CLINICAL_TRIALS trial_result · 2009-11-16Clinical Trial Update: Do Antibiotics Prevent Anal Fistulae Formation? [NA]
A completed trial from Ankara University evaluated whether antibiotics can prevent the formation of anal fistulae.