Anal Cancer
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CLINICAL_TRIALS trial_result · 2025-04-15Clinical Trial Update: Engaging Practices and Communities in the Development of Interventions to Promote HPV Vaccine Uptake [NA]
A completed study from the University of Colorado, Denver investigates engaging practices and communities to develop interventions aimed at …
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CLINICAL_TRIALS trial_result · 2025-04-01Clinical Trial Update: Increasing Human Papillomavirus (HPV) Vaccine Uptake Via General Health Messaging [NA]
A completed clinical trial assessed whether general health messaging can increase uptake of the human papillomavirus (HPV) vaccine.
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CLINICAL_TRIALS trial_result · 2025-02-19Clinical Trial Update: Efficacy of Immunotherapy Plus a Drug in Patients With Progressive Advanced Mucosal Cancer of Different Locations [Phase 2]
A completed Phase 2 trial evaluating immunotherapy in combination with a second drug in patients with progressive advanced mucosal cancers a…
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: Efficacy, Immunogenicity, and Safety Study of the 9vHPV Vaccine in Japanese Males (V503-064) [Phase 3]
Phase 3 trial evaluating the efficacy, immunogenicity, and safety of Gardasil 9 in Japanese males has completed and results have been posted…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: A Phase III Study to Evaluate the Efficacy, Immunogenicity and Safety of the 9-valent HPV Vaccine in Chinese Males [Phase 3]
Phase III trial in Chinese males evaluating the efficacy, immunogenicity and safety of the 9-valent HPV vaccine for HPV-related diseases.
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: The Prevent Anal Cancer Self-Swab Study [NA]
The document notes that the Prevent Anal Cancer Self-Swab Study has completed and posted results, evaluating a self-swab approach for anal c…
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CLINICAL_TRIALS trial_result · 2024-11-01Clinical Trial Update: Dose Escalation Trial of Endoluminal High-Dose-Rate Brachytherapy With Concurrent Chemotherapy for Rectal or Anal Cancer in Patients With Recurrent Disease or Undergoing Non-Operative Management [Phase 1]
Phase 1 dose-escalation study of endoluminal high-dose-rate brachytherapy with concurrent chemotherapy for rectal or anal cancer has complet…
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: Multilevel Interventions to Enhance Provider Recommendations for HPV Vaccination [NA]
This completed clinical trial evaluated multilevel interventions to enhance provider recommendations for HPV vaccination, with results poste…
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: A Chatbot Intervention for Reducing HPV Vaccine Hesitancy [NA]
Completed clinical trial evaluating a chatbot intervention to reduce HPV vaccine hesitancy, with results posted on 2024-10-21. Sponsor: Univ…
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: Radiotherapy Assessments During Intervention ANd Treatment (RADIANT)
Clinical trial update for the RADIANT study evaluating radiotherapy assessments during intervention and treatment; the trial covers multiple…
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine INO-3112 and Durvalumab in Treating Patients With Recurrent or Metastatic Human Papillomavirus Associated Cancers [Phase 2]
Phase 2 study evaluating INO-3112 (DNA plasmid encoding interleukin-12 and HPV DNA plasmids) with Durvalumab in patients with recurrent or m…
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: The Prevent Anal Cancer Palpation Study [NA]
A completed clinical trial sponsored by the Medical College of Wisconsin evaluating palpation-based approaches related to anal cancer preven…
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: Safety, Tolerability and Pharmacokinetics Investigation of Stimotimagene Copolymerplasmid [Phase 1]
Phase 1 trial evaluating safety, tolerability, and pharmacokinetics of Stimotimagene Copolymerplasmid in multiple cancer types; the study ha…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Adaptation Of An HPV Education Resource To Promote HPV Vaccination
Clinical trial update describing the adaptation of an HPV education resource to promote HPV vaccination; the study has completed and results…
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CLINICAL_TRIALS trial_result · 2024-03-15Clinical Trial Update: A Message Framing Intervention for Increasing Parental Acceptance of Human Papillomavirus Vaccination [NA]
Completed clinical trial evaluating a message framing intervention to increase parental acceptance of HPV vaccination.
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CLINICAL_TRIALS trial_result · 2024-01-11Clinical Trial Update: Trial To Test Safety And Efficacy Of Vaccination For Incurable HPV 16-Related Oropharyngeal, Cervical And Anal Cancer [Phase 1, Phase 2]
Phase 1/2 trial evaluating safety and efficacy of a vaccination targeting HPV16-related cancers in head and neck, cervical, and anal cancers…
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CLINICAL_TRIALS trial_result · 2023-11-18Clinical Trial Update: Combination Immunotherapy in Subjects With Advanced HPV Associated Malignancies [Phase 1, Phase 2]
This clinical trial update reports Phase 1/2 results for a combination immunotherapy regimen in adults with advanced HPV-associated cancers.…
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CLINICAL_TRIALS trial_result · 2023-10-05Clinical Trial Update: Proton Therapy in Reducing Toxicity in Anal Cancer [Phase 2]
This document provides an update on a Phase 2 clinical trial evaluating proton therapy to reduce toxicity in anal cancer. The trial is activ…
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: Cisplatin and Fluorouracil Compared With Carboplatin and Paclitaxel in Treating Patients With Inoperable Locally Recurrent or Metastatic Anal Cancer [Phase 2]
Phase 2 trial comparing cisplatin/fluorouracil versus carboplatin/paclitaxel in patients with inoperable locally recurrent or metastatic ana…
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CLINICAL_TRIALS trial_result · 2023-06-12Clinical Trial Update: Pembrolizumab in Metastatic Anal Cancer [Phase 2]
Phase 2 trial of pembrolizumab in metastatic anal cancer completed; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-03-20Clinical Trial Update: A Phase 2 Study of Axalimogene Filolisbac (ADXS11-001) in Participants With Carcinoma of the Anorectal Canal [Phase 2]
Phase 2 study of Axalimogene Filolisbac (ADXS11-001) in anorectal canal carcinoma completed; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2022-12-02Clinical Trial Update: Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade Lesions [Phase 3]
Phase 3 clinical trial update on treatment to prevent anal cancer in people with HIV and anal high-grade intraepithelial lesions; results ha…
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CLINICAL_TRIALS trial_result · 2022-09-30Clinical Trial Update: Anal HPV Tests in Screening for Cell Changes in the Anus in Patients With HIV [NA]
Clinical trial update on anal HPV tests for screening cell changes in the anus among people with HIV; study status completed with results po…
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CLINICAL_TRIALS trial_result · 2022-04-05Clinical Trial Update: Recombinant Human Papillomavirus Nonavalent Vaccine in Preventing Human Papilloma Virus in Younger Healthy Participants [Phase 2]
Phase 2 trial update on the recombinant human papillomavirus nonavalent vaccine for preventing HPV infection in younger healthy participants…
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CLINICAL_TRIALS trial_result · 2022-02-28Clinical Trial Update: M7824 in Subjects With HPV Associated Malignancies [Phase 2]
Phase 2 trial update for M7824 in HPV-associated malignancies completed with results posted in 2022.