Anal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-18Clinical Trial Results: HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers [Phase 1, Phase 2]
Phase 1/2 trial evaluating HPV vaccine PRGN-2009 alone or with anti-PD-L1/TGF-beta trap M7824 in HPV-associated cancers; study completed wit…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Edtech-HPV: A Community Approach Using Education and Technology to Increase HPV Vaccination [NA]
Clinical trial update on an education- and technology-based program to increase HPV vaccination uptake among parents; the study is currently…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Vaginal DHEA to Improve Vaginal Health After Radiation for Women With Gynecologic, Anal or Rectal Cancer [Phase 2]
A Phase 2 clinical trial evaluating vaginal DHEA to improve vaginal health after radiation in women with gynecologic, anal, or rectal cancer…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Self-sampling to Optimize Anal Lesion Outcomes [NA]
This clinical trial update notes ongoing recruitment for a study evaluating self-sampling to optimize outcomes in anal cancer. The study is …
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: HPV-16/18 E6/E7-Specific T Lymphocytes, Relapsed HPV-Associated Cancers, HESTIA [Phase 1]
Phase 1 trial HESTIA evaluating HPV-16/18 E6/E7-specific T lymphocytes in relapsed HPV-associated cancers has completed.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Lenvatinib and Pembrolizumab to Treat Patients With Anal or Rectum Cancer That Has Gotten Worse After Initial Treatment [Phase 2]
Clinical trial update announcing a phase 2 study of lenvatinib in combination with pembrolizumab for anal or rectal cancer that progressed a…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Assessment of Sexual Quality of Life Following Local Treatment (Radiotherapy With or Without Surgery) in Patients With HPV-positive Pelvic Cancer: a Descriptive Longitudinal Study [NA]
Describes a descriptive longitudinal study assessing sexual quality of life after local treatment (radiotherapy with or without surgery) in …
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer [Phase 3]
This is a Phase 3 clinical trial update evaluating nivolumab after combined modality therapy for high-risk stage II-IIIB anal cancer; the tr…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Phase 2 Trial Of Sacituzumab Tirumotecan For Treatment Of Refractory Metastatic Or Unresectable Squamous Cell Carcinoma Of The Anus/Rectum [Phase 2]
A Phase 2 clinical trial is evaluating Sacituzumab Tirumotecan for refractory metastatic or unresectable squamous cell carcinoma of the anus…
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CLINICAL_TRIALS other · 2026-04-06Clinical Trial Update: A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers [Phase 1, Phase 2]
This clinical trial update covers a Phase 1/2 study of a combination immunotherapy regimen for advanced cancers, including HPV-associated ma…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: DESTINY-PANTUMOUR04
Clinical trial update for the DESTINY-PANTUMOUR04 study sponsored by AstraZeneca, evaluating trastuzumab deruxtecan across multiple cancer t…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: The Effect of a Transtheoretical Model-Based Educational Intervention on First-Year Nursing Students' HPV Knowledge, Health Beliefs, and Vaccination Behavior Intentions [NA]
The study tests whether a transtheoretical model-based educational intervention improves HPV knowledge, health beliefs, and vaccination inte…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AMC
AIDS Malignancy Consortium completed a study evaluating a screening tool to describe HIV-related cancer burden and patient characteristics, …
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study [Phase 2]
Phase 2 DECREASE study is evaluating lower-dose chemoradiation for early-stage anal cancer. The trial is currently active but not recruiting…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Study of Pembrolizumab, Carboplatin, Paclitaxel, and Radiation for the Treatment of Early-Stage Anal Cancer [Phase 2]
This clinical trial update describes a Phase 2 study evaluating pembrolizumab in combination with carboplatin, paclitaxel, and radiation for…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Improving Clinic Delivery of HIV-related Anal Health Services [NA]
This clinical trial update describes a study led by Albert Einstein College of Medicine to improve clinic delivery of HIV-related anal healt…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Interpersonal Communication Training and Vaccination Workflow Training Alone and in Combination to Improve Communication and Recommendations About HPV Vaccination in Pharmacies, IMPACT HPV Trial [NA]
A clinical trial update describing the IMPACT HPV trial assessing interpersonal communication training and vaccination workflow training in …
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Culturally Targeted Health Communication and Receptivity to the Human Papillomavirus Vaccine Among Parents in Flint, MI [NA]
Michigan State University-sponsored trial in Flint is evaluating culturally targeted health communication to increase parental receptivity t…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Intrafractional Vaginal Dilation in Anal Cancer Patients Undergoing Pelvic Radiotherapy [NA]
A clinical trial investigating intrafractional vaginal dilation in anal cancer patients undergoing pelvic radiotherapy; recruitment is ongoi…
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Engaging Clinical Champions to Improve HPV Vaccination [NA]
This clinical trial update reports completion of a study evaluating engaging clinical champions to improve HPV vaccination uptake.
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Detecting HPV DNA in Anal and Cervical Cancers
A University of Chicago clinical trial is examining HPV DNA detection in anal and cervical cancers and is currently recruiting participants.
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: Extended Follow Up of Young Women in Costa Rica Who Received Vaccine for Human Papillomavirus Types 16 and 18 and Unvaccinated Controls
This clinical trial update presents extended follow-up data from a Costa Rica study of an HPV-16/18 vaccine in young women. It compares vacc…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers [Phase 1, Phase 2]
Clinical trial update for an E7 TCR-T cell therapy being studied in locoregionally advanced HPV-associated cancers. Recruitment is ongoing f…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers [Phase 2]
Phase 2 study of E7-targeted TCR-T cell immunotherapy for HPV-associated cancers is currently recruiting. The sponsor is Christian Hinrichs …
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Concordance and Acceptability of Self-screening Compared to Screening Carried Out by a Health Professional for HPV, a Risk Factor for Anal Cancer, by Swab in People Living With HIV. A Randomized Controlled Crossover Study [NA]
ClinicalTrials.gov entry for a randomized crossover study comparing self-swabbing versus clinician-swab screening for human papillomavirus (…