Alcoholic Hepatitis
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CLINICAL_TRIALS trial_result · 2019-02-19Clinical Trial Update: To Assess Safety/Efficacy of ELAD in Subjects w/ Severe Acute Alcoholic Hepatitis (sAAH) and Lille Score Failure [Phase 3]
A Phase 3 trial evaluating ELAD for severe acute alcoholic hepatitis with Lille score failure was terminated, and the study results were pos…
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Assess Safety and Efficacy of ELAD (Extracorporeal Liver Assist System) in Subjects With Alcohol-Induced Liver Failure [Phase 3]
Phase 3 trial evaluating the safety and efficacy of the Extracorporeal Liver Assist System (ELAD) in acute alcoholic hepatitis has completed…
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CLINICAL_TRIALS trial_result · 2019-02-06Clinical Trial Update: Selonsertib in Combination With Prednisolone Versus Prednisolone Alone in Participants With Severe Alcoholic Hepatitis (AH) [Phase 2]
Phase 2 trial comparing Selonsertib plus prednisolone versus prednisolone alone in severe alcoholic hepatitis has completed, with results po…
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CLINICAL_TRIALS trial_result · 2019-02-01Clinical Trial Update: Fecal Microbiota Transplantation in Severe Alcoholic Hepatitis- Assessment of Impact on Prognosis and Short-term Outcome [NA]
Clinical trial update describing a study of fecal microbiota transplantation in severe alcoholic hepatitis to assess its impact on prognosis…
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CLINICAL_TRIALS trial_result · 2019-01-25Clinical Trial Update: Randomized, Open-Label, Multicenter, Controlled, Pivotal Study to Assess Safety and Efficacy of ELAD in Subjects w/ AILD [Phase 3]
Phase 3 randomized pivotal trial evaluating ELAD for Acute Alcoholic Hepatitis was terminated, with results posted in January 2019.
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CLINICAL_TRIALS trial_result · 2018-10-25Clinical Trial Update: A Safety and Efficacy Study of Mycophenolate Mofetil and Rilonacept in Patients With Alcoholic Hepatitis [Phase 2]
A Phase 2 safety and efficacy trial evaluated the combination of mycophenolate mofetil and rilonacept in patients with alcoholic hepatitis, …
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CLINICAL_TRIALS trial_result · 2018-10-12Clinical Trial Update: GCSF in Alcoholic Hepatitis [Phase 4]
Phase 4 clinical trial update for GCSF in alcoholic hepatitis; status currently unknown.
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: Efficacy of G-CSF in the Management of Steroid Non-responsive Severe Alcoholic Hepatitis [NA]
A completed clinical trial assessed the efficacy of granulocyte colony-stimulating factor (G-CSF) for patients with steroid-nonresponsive se…
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CLINICAL_TRIALS trial_result · 2017-09-19Clinical Trial Update: G-CSF Plus NAC In Severe Alcoholic Hepatitis [Phase 4]
Clinical trial update for G-CSF plus NAC in severe alcoholic hepatitis (Phase 4), status unknown.
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CLINICAL_TRIALS research · 2017-04-10Clinical Trial Update: Alcohol Diet and Drug Use Preceding Alcoholic Hepatitis
This clinical trial update discusses factors related to alcohol diet and drug use that may precede alcoholic hepatitis, sponsored by Univers…
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CLINICAL_TRIALS trial_result · 2017-01-19Clinical Trial Update: Randomised Open-label Multicenter Study Evaluating Ciprofloxacin in Severe Alcoholic Hepatitis [EARLY_Phase 1]
This document reports the completion of a randomized, open-label, multicenter Phase 1 study evaluating ciprofloxacin in severe alcoholic hep…
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CLINICAL_TRIALS trial_result · 2016-11-04Clinical Trial Update: Study of IDN-6556 in Patients With Severe Alcoholic Hepatitis and Contraindications to Steroid Therapy [Phase 2]
A Phase 2 study of IDN-6556 (emricasan) in patients with severe alcoholic hepatitis who have contraindications to steroid therapy was termin…
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CLINICAL_TRIALS research · 2016-11-04Clinical Trial Update: Effects of Rifaximin in Patients With Acute Alcoholic Hepatitis [Phase 2]
A Phase 2 clinical trial evaluating rifaximin in patients with acute alcoholic hepatitis is reported, with the trial status listed as UNKNOW…
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CLINICAL_TRIALS trial_result · 2016-09-12Clinical Trial Update: Effects of Prednisolone and Pentoxifylline on the Regulation of Urea Synthesis in Alcoholic Hepatitis
A completed clinical trial evaluating the effects of prednisolone and pentoxifylline on the regulation of urea synthesis in alcoholic hepati…
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CLINICAL_TRIALS trial_result · 2016-07-15Clinical Trial Update: The Effect of High Dose Vitamin C on the Liver Function in Chronic Hepatitis Patients [Phase 4]
Phase 4 clinical trial evaluating the effect of high-dose vitamin C on liver function in patients with chronic hepatitis; results were poste…
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CLINICAL_TRIALS research · 2016-06-10Clinical Trial Update: Meta-Analysis of Drug Therapy in Patients With Severe Alcoholic Hepatitis
This document summarizes a meta-analysis of drug therapies used in patients with severe alcoholic hepatitis. It provides an updated assessme…
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CLINICAL_TRIALS trial_result · 2016-04-11Clinical Trial Update: Pharmacokinetic and Pharmacodynamic Study of IDN-6556 in ACLF [Phase 2]
Phase 2 pharmacokinetic and pharmacodynamic study of IDN-6556 in acute liver failure conditions was terminated, with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2015-09-15Clinical Trial Update: Efficacy of Combination Therapy of Glucocorticoids and Bovine Colostrum in Treatment of Severe Alcoholic Hepatitis. [Phase 2]
A Phase 2 trial evaluated the efficacy of combining glucocorticoids with bovine colostrum to treat severe alcoholic hepatitis defined by Mad…
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CLINICAL_TRIALS research · 2015-06-30Clinical Trial Update: Rifaximin Use in Severe Alcoholic Hepatitis [Phase 3]
Update on a Phase 3 trial evaluating rifaximin for severe alcoholic hepatitis; current status is not disclosed in the provided snippet.
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CLINICAL_TRIALS trial_result · 2015-04-29Clinical Trial Update: Efficacy and Safety of MG in the Patients With Alcoholic Fatty Liver Disease and Alcoholic Hepatitis [Phase 2]
Phase 2 clinical trial assessing efficacy and safety of MG in patients with alcoholic fatty liver disease and alcoholic hepatitis has been c…
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CLINICAL_TRIALS trial_result · 2015-01-28Clinical Trial Update: Effect of Probiotics on Gut-Liver Axis of Alcoholic Hepatitis [Phase 4]
A Phase 4 clinical trial is evaluating the effect of probiotics on the gut-liver axis in alcoholic hepatitis; current status is unknown.
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CLINICAL_TRIALS trial_result · 2014-11-11Clinical Trial Update: Metadoxine as a Therapy for Severe Alcoholic Hepatitis [Phase 4]
Phase 4 clinical trial evaluating metadoxine for severe alcoholic hepatitis has completed.
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CLINICAL_TRIALS other · 2014-06-03Clinical Trial Update: Liver Transplantation in Alcoholic Hepatitis
The clinical trial evaluating liver transplantation for alcoholic hepatitis has been suspended.
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CLINICAL_TRIALS trial_result · 2014-05-29Clinical Trial Update: Efficacy and Safety of S-adenosyl-l-methionine in Treatment of Alcoholic Hepatitis With Cholestasis [Phase 4]
A Phase 4 clinical trial is evaluating the efficacy and safety of S-adenosyl-L-methionine for alcoholic hepatitis with cholestasis.
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CLINICAL_TRIALS trial_result · 2014-05-13Clinical Trial Update: Pentoxifylline for Acute Alcoholic Hepatitis (AAH) [Phase 1]
A Phase 1 trial of pentoxifylline for acute alcoholic hepatitis was terminated, and results were posted in 2014.