Alcoholic Hepatitis
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: Intestinal Microbiota Profiling in Severe Acute Alcoholic Hepatitis Patients [NA]
A recruiting clinical trial investigating intestinal microbiota profiling in patients with severe alcoholic hepatitis, including those treat…
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: Short Course Steroids in Alcohol Associated Hepatitis [Phase 3]
A Phase 3 clinical trial evaluating short-course steroid therapy for alcoholic hepatitis is currently recruiting. The sponsor is the Asian I…
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CLINICAL_TRIALS trial_result · 2025-03-11Clinical Trial Update: IL-1 Signal Inhibition in Alcoholic Hepatitis [Phase 2]
A Phase 2 trial evaluating an IL-1 signaling inhibitor for alcoholic hepatitis has completed and posted results.
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: Effect of Alpha-1 Antitrypsin Supplementation on Alcohol-Associated Hepatitis [Phase 2]
Phase 2 clinical trial is investigating whether alpha-1 antitrypsin supplementation can improve outcomes in alcoholic hepatitis. The study i…
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: Recompensation in Alcohol Related Hepatitis [NA]
An ongoing clinical trial is recruiting to study recompensation in alcohol-related hepatitis (Alcoholic Hepatitis).
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CLINICAL_TRIALS research · 2025-01-23Clinical Trial Update: Safety Evaluation of Fecal Microbiota Transplantation in Severe Alcoholic Hepatitis [Phase 1, Phase 2]
A safety-focused update for a Phase 1/2 clinical trial evaluating fecal microbiota transplantation in adults with severe alcoholic hepatitis…
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CLINICAL_TRIALS research · 2025-01-23Clinical Trial Update: Randomized Controlled Trial of Mycophenolate Mofetil Versus Steroid Therapy in Alcoholic Hepatitis [NA]
A randomized controlled trial comparing mycophenolate mofetil with steroid therapy for alcoholic hepatitis is planned, with the study not ye…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Alcoholic Hepatitis Network Observational Study
Indiana University's Alcoholic Hepatitis Network observational study has completed and posted its results. The study focuses on Alcoholic He…
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CLINICAL_TRIALS trial_result · 2024-09-05Clinical Trial Update: A Phase 2b Study in Subjects With Alcoholic Hepatitis to Evaluate Safety and Efficacy of DUR-928 Treatment [Phase 2]
A Phase 2b study evaluating the safety and efficacy of DUR-928 in alcoholic hepatitis has completed.
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CLINICAL_TRIALS research · 2024-06-24Clinical Trial Update: Efficacy of Plasma Exchange Therapy vs Standard Medical Therapy in Severe Alcoholic Hepatitis With High Discriminant Function [NA]
This entry describes a clinical trial comparing plasma exchange therapy to standard medical therapy in severe alcoholic hepatitis with high …
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CLINICAL_TRIALS research · 2024-05-29Clinical Trial Update: Nutritional Interventions in Patients With Alcohol-associated Hepatitis [NA]
ClinicalTrials.gov update for a Western University study on nutritional interventions in patients with alcohol-associated hepatitis; the tri…
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CLINICAL_TRIALS trial_result · 2023-10-18Clinical Trial Update: DUR-928 in Patients With Alcoholic Hepatitis [Phase 2]
A Phase 2 clinical trial update for DUR-928 in patients with alcoholic hepatitis has completed.
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CLINICAL_TRIALS trial_result · 2023-07-28Clinical Trial Update: Trial of Anakinra (Plus Zinc) or Prednisone in Patients With Severe Alcoholic Hepatitis [Phase 2]
A Phase 2 trial evaluating Anakinra plus zinc versus prednisone in severe alcoholic hepatitis has completed and posted results.
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CLINICAL_TRIALS research · 2023-05-03Clinical Trial Update: Granulocyte Colony Stimulating Factor Four Week Plus N-Acetyl Cysteine in Severe Alcoholic Hepatitis [Phase 4]
A Phase 4 trial evaluating granulocyte colony-stimulating factor with N-acetylcysteine in severe alcoholic hepatitis has completed.
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CLINICAL_TRIALS trial_result · 2023-03-21Clinical Trial Update: Vitamin C Infusion for TReatment in Sepsis and Alcoholic Hepatitis [Phase 2]
Phase 2 clinical trial evaluating vitamin C infusion for treatment of alcoholic hepatitis and sepsis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-12-14Clinical Trial Update: A Research Study to Assess the Safety, Pharmacokinetics and Pharmacodynamics of DUR-928 in Patients With Alcoholic Hepatitis [Phase 2]
A Phase 2 study evaluating the safety, pharmacokinetics, and pharmacodynamics of DUR-928 in patients with alcoholic hepatitis has completed …
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CLINICAL_TRIALS trial_result · 2022-08-08Clinical Trial Update: Efficacy and Safety of G-CSF in Patients With Severe Alcoholic Hepatitis With Null or Partial Response to Steroid [Phase 3]
Phase 3 trial evaluating G-CSF in severe alcoholic hepatitis with incomplete steroid response; study terminated.
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CLINICAL_TRIALS trial_result · 2022-08-03Clinical Trial Update: Fecal Microbial Transplantation in Severe Alcoholic Hepatitis [Phase 3]
Phase 3 clinical trial update for fecal microbial transplantation in severe alcoholic hepatitis. Status is currently unknown.
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CLINICAL_TRIALS trial_result · 2022-03-02Clinical Trial Update: Novel Therapies in Moderately Severe Acute Alcoholic Hepatitis [NA]
Clinical trial update for Novel Therapies in Moderately Severe Acute Alcoholic Hepatitis; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2021-11-09Clinical Trial Update: N-ACetylcysteine to Reduce Infection and Mortality for Alcoholic Hepatitis [Phase 3]
Phase 3 trial evaluating N-acetylcysteine to reduce infection and mortality in alcoholic hepatitis is reported as an update with unknown cur…
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CLINICAL_TRIALS trial_result · 2021-09-29Clinical Trial Update: Pegfilgrastim in Patients With Alcoholic Hepatitis [Phase 2]
Phase 2 clinical trial update evaluating pegfilgrastim in patients with alcoholic hepatitis has completed.
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CLINICAL_TRIALS trial_result · 2020-12-10Clinical Trial Update: Efficacy Study of Anakinra, Pentoxifylline, and Zinc Compared to Methylprednisolone in Severe Acute Alcoholic Hepatitis [Phase 2, Phase 3]
A mixed-phase clinical trial assessing anakinra, pentoxifylline, and zinc versus methylprednisolone for severe acute alcoholic hepatitis has…
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CLINICAL_TRIALS trial_result · 2020-01-28Clinical Trial Update: Trial of Obeticholic Acid in Patients With Moderately Severe Alcoholic Hepatitis (AH) [Phase 2]
Phase 2 trial of obeticholic acid in moderately severe alcoholic hepatitis was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2020-01-27Clinical Trial Update: Safety and Efficacy of IMM 124-E for Patients With Severe Alcoholic Hepatitis [Phase 2]
Phase 2 clinical trial examining IMM 124-E for severe alcoholic hepatitis completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-09-09Clinical Trial Update: Use of F-652 in Patients With Alcoholic Hepatitis [Phase 1, Phase 2]
Clinical trial update for F-652 in alcoholic hepatitis (Phase 1/Phase 2); study completed with results posted in 2019.