Al Amyloidosis
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CLINICAL_TRIALS trial_result · 2019-05-16Clinical Trial Update: Open-label Extension Study of NEOD001 in Subjects With Light Chain (AL) Amyloidosis [Phase 2]
An open-label extension study for NEOD001 in AL amyloidosis was terminated; results were posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-04-05Clinical Trial Update: The PRONTO Study, a Global Phase 2b Study of NEOD001 in Previously Treated Subjects With Light Chain (AL) Amyloidosis [Phase 2]
Phase 2b study results for NEOD001 in previously treated AL amyloidosis completed; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2018-12-12Clinical Trial Update: Study in Subjects With Light Chain (AL) Amyloidosis [Phase 2]
Phase 2 clinical trial in AL amyloidosis (study terminated; results posted in 2018).
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CLINICAL_TRIALS trial_result · 2018-08-06Clinical Trial Update: Trial of High Dose Melphalan/Stem Cell Transplant With or Without Bortezomib [Phase 3]
Phase 3 trial evaluating high-dose melphalan with or without bortezomib in AL amyloidosis; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2018-04-25Clinical Trial Update: Immune Mobilization of Autologous Peripheral Blood Stem Cells Using Interleukin-2 and GM-CSF [Phase 1]
Phase 1 study evaluating mobilization of autologous peripheral blood stem cells using interleukin-2 and GM-CSF; the trial has completed.
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CLINICAL_TRIALS trial_result · 2018-03-21Clinical Trial Update: Epigallocatechingallate (EGCG) in Cardiac AL Amyloidosis [Phase 2]
Phase 2 trial evaluating Epigallocatechin gallate (EGCG) for cardiac AL amyloidosis has been terminated.
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CLINICAL_TRIALS trial_result · 2018-03-12Clinical Trial Update: Pomalidomide and Dexamethasone (PDex) in AL Amyloidosis [Phase 2]
Phase 2 trial evaluating pomalidomide with dexamethasone (PDex) for AL amyloidosis has completed.
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: Study of Bortezomib +HSCT in Primary Systemic Amyloidosis (AL) [NA]
This document notes the completion of a clinical trial evaluating the combination of bortezomib with hematopoietic stem cell transplantation…
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CLINICAL_TRIALS trial_result · 2017-03-22Clinical Trial Update: A Pilot Study of Lenalidomide, Melphalan and Dexamethasone in AL Amyloidosis [NA]
A pilot study of lenalidomide, melphalan, and dexamethasone in AL amyloidosis has completed, with results posted in March 2017.
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CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: A Trial for Systemic Light-chain (AL) Amyloidosis [Phase 3]
A Phase 3 trial for systemic light-chain (AL) amyloidosis has completed, according to ClinicalTrials.gov.
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CLINICAL_TRIALS trial_result · 2017-02-20Clinical Trial Update: Melphalan, Lenalidomide, and Dexamethasone in Treating Patients With Primary Systemic Amyloidosis [Phase 2]
This is a Phase 2 clinical trial update reporting results for melphalan, lenalidomide, and dexamethasone in AL amyloidosis (primary systemic…
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CLINICAL_TRIALS trial_result · 2017-02-20Clinical Trial Update: CC-5013 With or Without Dexamethasone in Treating Patients With Primary Systemic Amyloidosis [Phase 2]
Phase 2 trial evaluating lenalidomide (CC-5013) with or without dexamethasone for AL amyloidosis; results were posted.
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CLINICAL_TRIALS trial_result · 2017-01-27Clinical Trial Update: 2nd Autologous Stem Cell Transplant in Patients With Persistent/Recurrent (AL) Amyloidosis [Phase 2]
Phase 2 trial update evaluating a second autologous stem cell transplant in patients with persistent or recurrent AL amyloidosis, with resul…
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CLINICAL_TRIALS trial_result · 2015-07-24Clinical Trial Update: Allo SCT in Amyloidosis Non-interventional Study
Completed non-interventional study evaluating allogeneic stem cell transplantation in patients with AL amyloidosis.
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CLINICAL_TRIALS trial_result · 2015-03-25Clinical Trial Update: Risk-adapted Therapy for Primary Systemic (AL) Amyloidosis [Phase 2]
Phase 2 trial evaluating risk-adapted therapy for primary systemic AL amyloidosis; the study status is completed.
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: S9628 Dexamethasone Plus Interferon Alfa in Treating Patients With Primary Systemic Amyloidosis [Phase 2]
Phase 2 SWOG trial evaluating dexamethasone plus interferon alfa in AL amyloidosis has completed enrollment. The update does not provide det…
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CLINICAL_TRIALS trial_result · 2014-01-22Clinical Trial Update: Long-term Outcomes of Patients With Primary Amyloidosis After Stem Cell Transplantation
This update reports long-term outcomes for patients with AL amyloidosis who underwent autologous stem cell transplantation. It includes surv…
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CLINICAL_TRIALS trial_result · 2013-11-29Clinical Trial Update: Bortezomib and Dexamethasone Followed by ASCT Compared With ASCT Alone in Treating Patients With AL Amyloidosis [Phase 3]
Phase 3 trial comparing bortezomib and dexamethasone followed by autologous stem cell transplant versus autologous stem cell transplant alon…
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CLINICAL_TRIALS trial_result · 2013-11-25Clinical Trial Update: A Trial of Treatment With Lenalidomide-Melphalan-Dexamethasone in Patients With Primary (AL) Amyloidosis [Phase 2]
Phase 2 trial evaluating lenalidomide with melphalan and dexamethasone in AL amyloidosis has completed.
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CLINICAL_TRIALS trial_result · 2013-09-19Clinical Trial Update: Human Immune Globulin in Treating Patients With Primary Amyloidosis That is Causing Heart Dysfunction [Phase 1, Phase 2]
This clinical trial update covers a Phase 1/2 study evaluating Human Immune Globulin for AL amyloidosis-related heart dysfunction. Results w…
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CLINICAL_TRIALS trial_result · 2013-09-18Clinical Trial Update: Radioimmunoimaging of Light Chain (AL) Amyloidosis [Phase 1]
The update reports completion of a Phase 1 trial evaluating a radioimmunoimaging approach for AL amyloidosis.
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CLINICAL_TRIALS trial_result · 2013-09-18Clinical Trial Update: Radioimmunoimaging of AL Amyloidosis [Phase 1]
This clinical trial update reports the completion of a Phase 1 study evaluating a radioimmunoimaging approach for AL amyloidosis.
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Melphalan, Thalidomide, and Dexamethasone in Treating Patients With Newly Diagnosed, Previously Untreated Primary Systemic Amyloidosis [Phase 2]
A Phase 2 clinical trial evaluating the combination of melphalan, thalidomide, and dexamethasone in patients with newly diagnosed primary sy…
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CLINICAL_TRIALS trial_result · 2012-12-05Clinical Trial Update: Bortezomib, Cyclophosphamide, and Dexamethasone in Treating Patients With Primary Systemic Light Chain Amyloidosis [Phase 2]
A Phase 2 trial evaluating bortezomib, cyclophosphamide, and dexamethasone in patients with AL amyloidosis has completed, with results poste…
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CLINICAL_TRIALS trial_result · 2012-11-12Clinical Trial Update: 4'-Iodo-4'-Deoxydoxorubicin in Treating Patients With Primary Systemic Amyloidosis [Phase 2]
A Phase 2 clinical trial evaluating 4'-Iodo-4'-Deoxydoxorubicin in patients with AL amyloidosis and related plasma cell neoplasms has comple…