Al Amyloidosis

• CLINICAL_TRIALS research · 2025-08-06
  Clinical Trial Update: Screening for AL Amyloidosis in Smoldering Multiple Myeloma

  This clinical trial update indicates ongoing recruitment for a study screening for AL amyloidosis in people with smoldering multiple myeloma…

• CLINICAL_TRIALS research · 2025-08-05
  Clinical Trial Update: Multimodal Radiomics Model (18F-FAPI PET/CT + CMR) for AL Cardiac Amyloidosis Prognosis

  A clinical trial update describes a multimodal radiomics model using 18F-FAPI PET/CT plus cardiac MRI to predict prognosis in AL amyloidosis…

• CLINICAL_TRIALS research · 2025-07-25
  Clinical Trial Update: Safety and Efficacy of Metabolically Armed BCMA CAR-T Cells (Meta10-BCMA) in the Treatment of r/r Plasma Cell Neoplasms Clinical Research [EARLY_Phase 1]

  This document reports an EARLY Phase 1 clinical trial evaluating Meta10-BCMA for relapsed/refractory plasma cell neoplasms. The therapy uses…

• CLINICAL_TRIALS research · 2025-07-23
  Clinical Trial Update: Teclistamab in Newly Diagnosed Mayo Stage IIIB AL Amyloidosis [Phase 2]

  Phase 2 clinical trial evaluating teclistamab in newly diagnosed Mayo Stage IIIB AL amyloidosis is currently recruiting.

• CLINICAL_TRIALS research · 2025-07-10
  Clinical Trial Update: Study of NXC-201 CAR-T in Patients With Light Chain (AL) Amyloidosis [Phase 1, Phase 2]

  Nexcella Inc. is conducting a Phase 1/2 clinical trial of the CAR-T therapy NXC-201 to treat AL amyloidosis, currently recruiting.

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• CLINICAL_TRIALS research · 2025-07-09
  Clinical Trial Update: Study of Eque-cel CAR-T Therapy in Newly Diagnosed Severe AL Amyloidosis [Phase 2]

  This clinical trial update notes a Phase 2 study of Eque-cel CAR-T therapy for newly diagnosed severe AL amyloidosis, which is currently not…

• CLINICAL_TRIALS research · 2025-07-08
  Clinical Trial Update: Venetoclax-Dexamethasone in Relapsed and/or Refractory t(11;14) Amyloidosis [Phase 1, Phase 2]

  A Phase 1/2 trial evaluating the combination of venetoclax and dexamethasone for relapsed or refractory AL amyloidosis with t(11;14) translo…

• CLINICAL_TRIALS research · 2025-03-03
  Clinical Trial Update: The Norwegian Immunotherapy in Multiple Myeloma Study

  The Norwegian immunotherapy in multiple myeloma study (NCT06855121) is currently recruiting. It targets multiple myeloma, plasma cell leukem…

• CLINICAL_TRIALS research · 2025-01-10
  Clinical Trial Update: BCMA/CD3 BiTE for RRAL or NDAL Amyloidosis With Insufficient Depth of Hematologic Response After Induction Therapy [NA]

  Clinical trial update for a BCMA/CD3 bispecific T-cell engager in AL amyloidosis (relapsed/refractory or newly diagnosed) noting insufficien…