Aggressive Periodontitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: The Effect of Non-Surgical Periodontal Treatment on Systemic Inflammatory Markers and Lipid Profile in Young Adults With Severe Periodontitis [NA]
A completed clinical trial evaluating whether non-surgical periodontal treatment influences systemic inflammatory markers and lipid profile …
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Single-cell and Spatial Transcriptomic Profiling of Gingival Tissues in Aggressive and Chronic Periodontitis: Deciphering Cellular Heterogeneity and Inflammatory Microenvironment Features
This clinical trial uses single-cell and spatial transcriptomics to profile gingival tissues from individuals with aggressive and chronic pe…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: B Cell Functions in Periodontitis
A clinical trial is recruiting to study B cell functions in periodontitis, enrolling participants with chronic periodontitis or aggressive p…
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CLINICAL_TRIALS research · 2024-06-27Clinical Trial Update: Chronic Presence of Epstein Barr Virus in Sulcular and Junctional Epithelial Tissue From Gingiva is Associated With Severe Periodontitis [NA]
This clinical trial update reports an association between the chronic presence of Epstein-Barr Virus in gingival tissue and severe periodont…
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CLINICAL_TRIALS research · 2023-08-04Clinical Trial Update: Transplantation of Bone Marrow Mesenchymal Stromal Cells for Periodontal Regeneration [Phase 1, Phase 2]
A clinical trial evaluating bone marrow mesenchymal stromal cell transplantation for periodontal regeneration in chronic periodontal disease…
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CLINICAL_TRIALS trial_result · 2021-09-17Clinical Trial Update: Concentrated Growth Factors in Treatment of Intrabony Defects in Localized Aggressive Periodontitis [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating concentrated growth factors for treating intrabony defects in localized aggressive periodontitis has c…
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CLINICAL_TRIALS trial_result · 2021-07-29Clinical Trial Update: Omega-3 Plus Low-dose Aspirin Daily Supplementation in Non-surgical Therapy to Treat Aggressive Periodontitis [Phase 2, Phase 3]
A phase 2/3 clinical trial evaluated omega-3 with low-dose aspirin as a daily supplement in non-surgical therapy for aggressive periodontiti…
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CLINICAL_TRIALS research · 2020-11-17Clinical Trial Update: Omega-3 Fatty Acids Plus Low-dose Aspirin Daily Supplementation in Surgical Therapy to Treat Aggressive Periodontitis [Phase 2, Phase 3]
A phase 2/3 trial evaluating omega-3 fatty acids plus low-dose aspirin as an adjunctive supplement in surgical therapy for aggressive period…
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CLINICAL_TRIALS trial_result · 2020-09-07Clinical Trial Update: Two Different Antibiotic Agents to Treat Generalized Aggressive Periodontitis [Phase 2, Phase 3]
Phase 2 and Phase 3 trial update evaluating two antibiotic agents for aggressive periodontitis; study completed with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-06-09Clinical Trial Update: Evaluation of Efficacy of Full-mouth Disinfection in Generalized Aggressive Periodontitis Patients [Phase 4]
Phase 4 trial update evaluating the efficacy of full-mouth disinfection in generalized aggressive periodontitis.
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CLINICAL_TRIALS trial_result · 2019-05-29Clinical Trial Update: Efficacy of Three Antibiotic Protocols for Aggressive Periodontitis Treatment [Phase 4]
Phase 4 clinical trial update evaluating three antibiotic protocols for aggressive periodontitis.
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CLINICAL_TRIALS trial_result · 2018-11-02Clinical Trial Update: Alternative Antibiotic Regime in the Treatment of GAgP [Phase 4]
Phase 4 clinical trial evaluating an alternative antibiotic regimen for Generalized Aggressive Periodontitis and Aggressive Periodontitis ha…
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CLINICAL_TRIALS trial_result · 2018-11-01Clinical Trial Update: Doxycycline in the Treatment of Aggressive Periodontitis [Phase 1, Phase 2]
Clinical trial updates on doxycycline for aggressive periodontitis across Phase 1 and Phase 2 have been completed.
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CLINICAL_TRIALS trial_result · 2018-10-11Clinical Trial Update: Enamel Matrix Proteins in the Treatment of Intrabony Defects in Patients With Aggressive and Chronic Periodontitis [Phase 4]
Phase 4 clinical trial evaluating enamel matrix proteins for treating intrabony defects in patients with aggressive periodontitis.
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CLINICAL_TRIALS research · 2017-11-13Clinical Trial Update: Clinical and Radiographic Evaluation of Guided Tissue Regeneration With Radiation-sterilized Allogenic Bone Grafts or Xenogenic Grafts for the Treatment of Intrabony Defects in Aggressive Periodontitis [NA]
The document outlines a clinical trial evaluating guided tissue regeneration with radiation-sterilized allogenic bone grafts or xenogenic gr…
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CLINICAL_TRIALS trial_result · 2017-10-17Clinical Trial Update: Clarithromycin as Adjuvant to Periodontal Debridement [NA]
This clinical trial update reports on using clarithromycin as an adjunct to periodontal debridement for aggressive periodontitis, with the s…
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CLINICAL_TRIALS research · 2017-07-18Clinical Trial Update: Immediate Implant Placement in Aggressive Periodontitis [NA]
This clinical trial update discusses immediate implant placement in aggressive periodontitis, but provides no phase or status details.
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CLINICAL_TRIALS trial_result · 2017-06-15Clinical Trial Update: Estimation of Pentrexin-3 Levels in GCF and Saliva of Patients With Periodontal Disease
This completed clinical trial from Cairo University evaluated Pentrexin-3 levels in gingival crevicular fluid and saliva of patients with ch…
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CLINICAL_TRIALS trial_result · 2017-02-24Clinical Trial Update: Effects of Er,Cr:YSGG, Diode Lasers on GCF Cytokines Levels [NA]
A completed clinical trial (NCT03034824) evaluated the effects of Er,Cr:YSGG and diode lasers on gingival crevicular fluid cytokine levels i…
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CLINICAL_TRIALS research · 2016-10-07Clinical Trial Update: Gingival Crevicular Fluid Levels Of Monocyte Chemoattractant Protein-1
A completed clinical trial examining gingival crevicular fluid levels of monocyte chemoattractant protein-1 in aggressive periodontitis.
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CLINICAL_TRIALS trial_result · 2016-06-30Clinical Trial Update: Frequency Of MCP-1 And CCR2 Gene Polymorphisms And Its Effect On Gene Expression In Patients With AgP
A completed clinical trial examined whether MCP-1 and CCR2 gene polymorphisms influence gene expression in patients with aggressive periodon…
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CLINICAL_TRIALS trial_result · 2016-03-16Clinical Trial Update: Smoking Influence on Apoptosis in Periodontitis
A completed clinical trial from Damascus University evaluated how smoking influences apoptosis in chronic periodontitis and aggressive perio…
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CLINICAL_TRIALS trial_result · 2015-10-05Clinical Trial Update: Nitro-oxidative Stress in Periodontitis
This update reports the completion of a clinical trial at Damascus University studying nitro-oxidative stress in chronic periodontitis and a…
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CLINICAL_TRIALS trial_result · 2014-11-04Clinical Trial Update: Immunolocalization of 1,25,Dihydroxyvitamin D3 in Aggressive Periodontitis Patients
A completed clinical trial investigated immunolocalization of 1,25-dihydroxyvitamin D3 in aggressive periodontitis patients.
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CLINICAL_TRIALS trial_result · 2014-07-15Clinical Trial Update: Effect of Surgical Therapy on RANKL/OPG (Osteoprotegerin) System
This completed clinical trial evaluated the effect of surgical therapy on the RANKL/OPG system in chronic periodontitis and aggressive perio…