Age-related Macular Degeneration
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: A Study of Danicopan in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration [Phase 2]
A Phase 2 study of Danicopan for geographic atrophy due to age-related macular degeneration was terminated, and results have been posted.
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: CNV in AMD Analyzed by OCT Angiography Under IntravitreaL Eylea (COCTAEyl)
This completed trial evaluated choroidal neovascularization in age-related macular degeneration using OCT angiography in eyes treated with i…
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Robotic Subretinal tPA Injection Study [NA]
This clinical trial update reports the completion of a robotic subretinal tissue plasminogen activator (tPA) injection study. It investigate…
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: Pivotal Trial of an Automated AI-based System for Early Diagnosis and Prediction of Late Age-related Macular Degeneration
A pivotal trial is being conducted to evaluate an automated AI-based system for early diagnosis and prediction of late age-related macular d…
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CLINICAL_TRIALS research · 2025-08-27Clinical Trial Update: Comparison of the Sensibility of Swept Source Optical Coherence Tomography Devices in the Detection of Neovascularisation in Large Pigment Epithelium Detachments
A clinical trial assessing the sensitivity of swept-source optical coherence tomography devices for detecting neovascularization in large pi…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: FOCUS: A Phase I/II First in Human Study to Evaluate the Safety and Efficacy of GT005 Administered in Subjects With Dry AMD [Phase 1, Phase 2]
The FOCUS study (GT005) in dry age-related macular degeneration was terminated in Phase 1/2, and results have been posted.
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: "My Eyes, My Light": Amar Chokh, Amar Alo
A clinical trial sponsored by Data Yakka, Inc. is currently recruiting to study treatments for glaucoma and diabetic retinopathy, among seve…
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CLINICAL_TRIALS research · 2025-08-21Clinical Trial Update: AMD and Validation Rod-Meditated Dark Adaptation With Everyday Task Performance [NA]
A Duke University study is recruiting participants with age-related macular degeneration to assess rod-mediated dark adaptation and its effe…
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CLINICAL_TRIALS trial_result · 2025-08-21Clinical Trial Update: Retinal Fundus Flavoprotein Fluorescence in Age Related Macular Degeneration [NA]
A completed clinical trial evaluated retinal fundus flavoprotein fluorescence in age-related macular degeneration, including geographic atro…
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CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: Smartphone Screening for Eye Diseases
University of Michigan is running a smartphone-based screening study for eye diseases and is currently enrolling by invitation, targeting gl…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: High Dose (HD) Aflibercept Switch in Neovascular Age-related Macular Degeneration (nAMD): to Load or Maintain (HEIRLOOM) [Phase 3]
Phase 3 trial HEIRLOOM evaluating high-dose aflibercept switching (load vs maintain) for wet/neovascular age-related macular degeneration.
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CLINICAL_TRIALS other · 2025-08-13Clinical Trial Update: Effect of Fu's Subcutaneous Needling for Age-related Macular Degeneration [EARLY_Phase 1]
A clinical trial update notes that a Phase 1 study of Fu's Subcutaneous Needling for age-related macular degeneration is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: EXPLORE: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005 [Phase 2]
The EXPLORE Phase II study evaluating two doses of GT005 for dry age-related macular degeneration was terminated. Results have been posted.
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CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: Stereotactic Radiotherapy for Wet AMD (STAR) [Phase 3]
Phase 3 trial STAR evaluating stereotactic radiotherapy for neovascular (wet) age-related macular degeneration has completed.
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of RQC for AMD [Phase 2]
The document reports the completion of a Phase 2 trial evaluating the safety and efficacy of RQC for age-related macular degeneration.
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Intravitreal Faricimab in Patients With Refractory Macular Edema [Phase 2]
Phase 2 trial update evaluating intravitreal faricimab for refractory macular edema in age-related macular degeneration.
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CLINICAL_TRIALS trial_result · 2025-07-29Clinical Trial Update: Comparing Post-intravitreal Injection Pain Scores Using Loteprednol, Bromfenac Sodium, and Artificial Tears Over a 24-hour Period [Phase 4]
Phase 4 trial comparing post-intravitreal injection pain scores when using loteprednol etabonate, bromfenac sodium, or artificial tears in p…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Strategies for Improving Linkage-to-Care After Eye Disease Screening [NA]
A UCSF-sponsored clinical trial is investigating strategies to improve linkage-to-care after eye disease screening, focusing on age-related …
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Village-Integrated Eye Worker Trial II [NA]
A UCSF-sponsored clinical trial update shows recruitment ongoing for Village-Integrated Eye Worker Trial II, studying age-related macular de…
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: The Impact of Artificial Lighting on the Visual Capacity of Patients With Age-Related Macular Degeneration
This clinical trial investigates how artificial lighting affects visual capacity in patients with age-related macular degeneration; recruitm…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Safety of BBC1501 Intravitreal Injection in Patients With Neovascular Age-Related Macular Degeneration (nAMD) [Phase 1]
Phase 1 clinical trial evaluating the safety of BBC1501 given as an intravitreal injection in patients with neovascular age-related macular …
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: Sildenafil for Treatment of Choroidal Ischemia [Phase 2]
This is a completed Phase 2 trial evaluating sildenafil for choroidal ischemia, with results posted in 2025; the study also involves vitelli…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: A Masked, Placebo-controlled Study to Assess Iptacopan in Age-related Macular Degeneration [Phase 2]
A masked, placebo-controlled Phase 2 trial of iptacopan for age-related macular degeneration is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: A Phase 1/2 Study of the Safety and Efficacy of BRX011 Oral Administration Once Daily in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the oral agent BRX011 for geographic atrophy due to age-related macular degeneration; the study is not…
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CLINICAL_TRIALS trial_result · 2025-06-24Clinical Trial Update: Microcurrent Stimulation Therapy for Nonexudative Age-related Macular Degeneration (i-SIGHT) [NA]
This clinical trial update notes the completion of a study evaluating microcurrent stimulation therapy for dry, nonexudative age-related mac…