Age-related Macular Degeneration
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Ocular Proteomics Testing In Chronic Atrophy [NA]
This clinical trial is recruiting to evaluate ocular proteomics testing in chronic atrophy associated with age-related macular degeneration.
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Evaluation of Kamuvudine-8 in Subjects With Geographic Atrophy [Phase 1, Phase 2]
A clinical trial update indicates Kamuvudine-8 is being evaluated for Geographic Atrophy in Phase 1/2 and the study is currently active but …
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Retinal Clinical Assessment With AI-derived Quantitative Information
This clinical trial update describes an AI-derived retinal imaging assessment intended to provide quantitative information across several re…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: SGLT2 Inhibitors in Geographic Atrophy [Phase 2]
A Phase 2 clinical trial is evaluating SGLT2 inhibitors for geographic atrophy, an advanced form of age-related macular degeneration, and is…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: Study to Evaluate a Pegcetacoplan (Syfovre®) Prefilled Syringe [Phase 3]
A Phase 3 trial evaluating pegcetacoplan (Syfovre) in a prefilled syringe for geographic atrophy secondary to age-related macular degenerati…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Impact of Non-Exudative Type 1 MNV on AMD Progression
This University of Utah–sponsored trial investigates whether non-exudative type 1 macular neovascularization influences the progression of a…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Natural History Study of Inherited Retinal Diseases
A natural history study of inherited retinal diseases sponsored by Zhongmou Therapeutics is currently recruiting. The study will examine ret…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Detection and Management of Sinusitis in a Single-center Prospective Cohort of Patients With Exudative AMD (SINE)
This clinical trial update describes a single-center prospective cohort study (SINE) investigating the detection and management of sinusitis…
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Efficacy Evaluation Study of BAT5906 and Lucentis® in Patients With Macular Degeneration [Phase 3]
Phase 3 efficacy evaluation comparing BAT5906 to Lucentis in neovascular age-related macular degeneration has completed, with efficacy data …
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Real-Life Clinical Outcomes of Aflibercept Biosimilar MY-1701P in the Treatment of Exudative Age-Related Macular Degeneration
A real-world clinical trial entry describing outcomes of the aflibercept biosimilar MY-1701P for exudative age-related macular degeneration,…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD [Phase 2]
A Phase 2 study evaluating ONL1204 for geographic atrophy associated with age-related macular degeneration is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Comparison of Cytokine Profiles in Aqueous Humor of Patients With Age Related Macular Degeneration (AMD) [NA]
The trial completed and reports on cytokine profiles in the aqueous humor of patients with age-related macular degeneration.
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: High-throughput Large-model-based AI-assisted Diagnosis Using OCT
A clinical trial update for a high-throughput AI system using OCT for retinal disease diagnosis; the study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: The Sahlgrenska Anti-VEGF Study [Phase 2]
Phase 2 clinical trial update on an anti-VEGF therapy for age-related macular degeneration; the study is currently active but not recruiting…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Pharmacogenomics of antiVEGF in Patients With Age-Associated Macular Degeneration (AMD) [Phase 3]
A Phase 3 clinical trial evaluating pharmacogenomics of anti-VEGF therapy in patients with neovascular (wet) age-related macular degeneratio…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: A Multiple Dose Study of AVD-104 for Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD) [Phase 2]
This document provides a Phase 2 multiple-dose trial update for AVD-104 in geographic atrophy secondary to age-related macular degeneration,…
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FDA approval · 2025-11-19FDA Approved: EYLEA HD — Supplemental Application (Regeneron Pharmaceuticals, Inc)
The FDA approved a supplemental application for EYLEA HD (aflibercept) by Regeneron, introducing a high-dose formulation.
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Artificial Intelligence-Aided Screening for Patients With Diabetic Retinopathy and Age-related Macular Degeneration in Family Medicine and Geriatric Medicine Outpatient Clinics [NA]
A clinical trial sponsored by National Taiwan University Hospital is testing AI-assisted screening for diabetic retinopathy and age-related …
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: High Resolution, High-speed Multimodal Ophthalmic Imaging [NA]
This clinical trial update describes recruitment for a study of high-resolution, high-speed multimodal ophthalmic imaging technologies evalu…
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CLINICAL_TRIALS other · 2025-11-17Clinical Trial Update: ReNEW:Phase 3 Study of Efficacy, Safety & Pharmacokinetics of Subcutaneous Injections of Elamipretide in Subjects With Dry Age-Related Macular Degeneration (Dry AMD) [Phase 3]
Phase 3 trial status update for subcutaneous elamipretide in dry age-related macular degeneration; the study is currently active but not rec…
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CLINICAL_TRIALS trial_result · 2025-11-14Clinical Trial Update: IAI Versus Sham as Prophylaxis Against Conversion to Neovascular AMD [Phase 2]
Phase 2 trial comparing IAI to sham prophylaxis to prevent conversion to neovascular Age-Related Macular Degeneration; results from the comp…
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FDA approval · 2025-11-12FDA Approved: BYOOVIZ — Supplemental Application (BIOGEN INC.)
The FDA approved a supplemental Biologics License Application for BYOOVIZ (ranibizumab-nuna) from Biogen, expanding regulatory clearance for…
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EMA withdrawal · 2025-10-30EMA Refused: Syfovre — Apellis Europe B.V.
The EMA refused to grant marketing authorization for Syfovre (pegcetacoplan) for geographic atrophy associated with age-related macular dege…
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CLINICAL_TRIALS trial_result · 2025-10-24Clinical Trial Update: An Extension Study to Evaluate the Long-term Safety and Efficacy of Pegcetacoplan (APL-2) in Subjects With Geographic Atrophy Secondary to AMD [Phase 3]
An extension study evaluating the long-term safety and efficacy of pegcetacoplan (APL-2) in geographic atrophy due to age-related macular de…
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CLINICAL_TRIALS research · 2025-10-24Clinical Trial Update: Scotoma Perimetry Oculomotor Training [NA]
The clinical trial evaluating Scotoma Perimetry Oculomotor Training for macular degeneration and central visual impairment has completed.