Age-related Macular Degeneration
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: A Prospective, Multicenter, Open-Label, Observational Phase 4 Study to Evaluate Real-World Safety, Tolerability, and Treatment Patterns of Pegcetacoplan (Syfovre) in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration
A Phase 4 prospective, multicenter, open-label observational study to evaluate real-world safety, tolerability, and treatment patterns of pe…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Visual Frailty in Ageing
University of Edinburgh-sponsored clinical trial is currently recruiting to study visual frailty in aging, examining how frailty and age-rel…
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FDA approval · 2026-02-27FDA Approved: IZERVAY — Supplemental Application (Astellas Pharma US, Inc.)
The FDA approved a supplemental application for IZERVAY (avacincaptad pegol) from Astellas Pharma US, expanding its label for geographic atr…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: EarLy Treatment Response in nEoVascular Macular Degeneration With Eylea 8mg: ELEV8 A Prospective Observational Open Label Study Investigating the Fluid Dynamics During Early Response to Aflibercept 8mg in Patients With Exudative Age-related Macular Degeneration (AMD).
A prospective, open-label observational study evaluating fluid dynamics during early response to aflibercept 8 mg (Eylea) in patients with e…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: A Study About the Safety of ASP3021 Eye Injections and if They Help People in Japan With Vision Loss From Age-related Macular Degeneration [Phase 4]
Phase 4 study in Japan evaluating the safety and potential efficacy of ASP3021 eye injections for vision loss due to Geographic Atrophy and …
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: A Snapshot Adaptive Optics and Hyperspectral Autofluorescence Fundus Camera for Age-Related Macular Degeneration (AMD)
This clinical trial update describes the use of a snapshot adaptive optics and hyperspectral autofluorescence fundus camera being investigat…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Prognostic Role of Macular Neovascular Membrane Subtype in Pneumatic Displacement of Macular Hemorrhages
A clinical trial investigating the prognostic role of macular neovascular membrane subtypes in pneumatic displacement of macular hemorrhages…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Active AMD Study to Improve Function in Veterans [NA]
A VA-sponsored clinical trial studying an intervention to improve function in age-related macular degeneration is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Evaluating the Relationship Between Function and Structure in ARCHER II-like Population Using Data From a Natural History Cohort
Completed study examining the relationship between function and structure in an ARCHER II–like population using data from a natural history …
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Retrospective Multicenter Real-world Observational Study of Switching to Aflibercept 8 mg in Patients With Refractory or Dependent Exudative Age-related Macular Degeneration
A multicenter, real-world retrospective observational study is planned to assess switching patients with refractory or dependent exudative a…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Lutein Iontophoresis in Intermediate AMD and Reticular Pseudodrusen - a Retrospective Study
A completed retrospective study evaluating lutein iontophoresis for intermediate age-related macular degeneration with reticular pseudodruse…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Study in Human iPSCs-derived RPE Cells Transplantation for Late-Stage AMD [Phase 1, Phase 2]
A Phase 1/2 clinical trial sponsored by The First Affiliated Hospital with Nanjing Medical University is evaluating transplantation of iPSC-…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Pivotal 1 Study of ABBV-RGX-314 (Also Known as RGX-314) Gene Therapy Administered Via Subretinal Delivery One Time in Participants With nAMD [Phase 2, Phase 3]
Clinical trial update for ABBV-RGX-314 (RGX-314) gene therapy in neovascular age-related macular degeneration, with Phase 2/Phase 3 pivotal …
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Efficacy of Faricimab in Patients With Subretinal Hyper-reflective Material [Phase 4]
This clinical trial update reports on the efficacy of faricimab in patients with age-related macular degeneration featuring subretinal hyper…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Home Monitoring in eAMD Treatment
A not-yet-recruiting clinical trial is exploring home monitoring for the treatment of exudative age-related macular degeneration.
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Repeated Low-Level Red-Light Therapy in Dry Age-Related Macular Degeneration [NA]
A clinical trial evaluates repeated low-level red-light therapy for dry age-related macular degeneration, with status not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-02-12Clinical Trial Update: Study to Assess the Adverse Events and How Intravitreal ABBV-6628 Moves Through the Body of Adult Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration [Phase 1, Phase 2]
An update on the ABBV-6628 intravitreal study in adults with geographic atrophy due to age-related macular degeneration, focusing on adverse…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Post-market Clinical Investigation of the SING IMT System, Model NG SI IMT 3X in Patients With End-stage Age-related Macular Degeneration [NA]
This document describes a post-market clinical investigation of the SING IMT System (Model NG SI IMT 3X) for end-stage age-related macular d…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: Surgery, Tissue Plasminogen Activator, Antiangiogenic Agents and Age Related Macular Degeneration Complications [NA]
A completed clinical trial evaluating surgery, intravitreal tissue plasminogen activator, and antiangiogenic therapy for subretinal haemorrh…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Factors in Learning And Plasticity: Healthy Vision [NA]
This clinical trial update describes a study of factors in learning and plasticity related to vision. It involves conditions such as central…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Factors in Learning And Plasticity: Macular Degeneration [NA]
A University of Alabama at Birmingham study on learning and plasticity in macular degeneration is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: A Phase 1 Study of ABF-101 in Single- and Multiple-Ascending Doses [Phase 1]
A Phase 1 clinical trial update for ABF-101 in single- and multiple-ascending dose cohorts is underway. The study targets age-related macula…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: A Phase 2 Efficacy and Safety Study of GAL-101, 2% Ophthalmic Solution in Non-foveal Geographic Atrophy Secondary to Non-neovascular AMD [Phase 2]
This document reports that GAL-101, a 2% ophthalmic solution developed by Galimedix Therapeutics, is being evaluated in a Phase 2 trial for …
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Mirabegron in Patients With Age-Related Macular Degeneration
A clinical trial is investigating mirabegron in patients with age-related macular degeneration (specifically dry AMD) and overactive bladder…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated With Age-Related Macular Degeneration [Phase 1, Phase 2]
An early-stage clinical trial is evaluating autologous induced pluripotent stem cell-derived retinal pigment epithelium transplantation for …