Age-related Macular Degeneration
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2014-12-31Clinical Trial Update: Evaluation of the Simplified Treat And Extend Regimen Using Ranibizumab in Exudative Age Related Macular Degeneration [NA]
Clinical trial update on evaluating a simplified Treat-and-Extend regimen with ranibizumab for exudative age-related macular degeneration.
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CLINICAL_TRIALS withdrawal · 2014-12-11Clinical Trial Update: Study of WA-NG Telescope Prosthesis in Patients With End-stage Age-related Macular Degeneration [NA]
The WA-NG Telescope Prosthesis trial for end-stage Age-related Macular Degeneration has been withdrawn.
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CLINICAL_TRIALS trial_result · 2014-12-05Clinical Trial Update: INTREPID - IRay Plus Anti-VEGF Treatment For Patients With Wet AMD [Phase 2]
INTREPID is a Phase 2 trial evaluating IRay Plus in combination with anti-VEGF treatment for wet age-related macular degeneration. The study…
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CLINICAL_TRIALS withdrawal · 2014-11-21Clinical Trial Update: Does Vascular Endothelial Growth Factor (VEGF) or Complement Factor H Gene Polymorphism Play a Role in the Treatment Success With VEGF Inhibitors in Patients With Choroidal NeoVascularization (CNV)? [NA]
This clinical trial examining whether VEGF or CFH gene polymorphisms influence response to VEGF inhibitors in choroidal neovascularization a…
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CLINICAL_TRIALS trial_result · 2014-11-20Clinical Trial Update: Low Vision Depression Prevention Trial for Age Related Macular Degeneration [Phase 3]
Phase 3 trial evaluating prevention of depression in age-related macular degeneration has completed, with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-11-18Clinical Trial Update: Study of Bimonthly VEGF Trap-Eye Compared to As-needed Administration or Other Therapy for Exudative Age-Related Macular Degeneration
A completed clinical trial sponsored by Stanford University comparing bimonthly VEGF Trap-Eye (aflibercept) dosing to as-needed administrati…
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CLINICAL_TRIALS trial_result · 2014-11-14Clinical Trial Update: Effects of Lutein Supplementation on Macular Pigment Optical Density and Visual Acuity in Patients With Age-related Macular Degeneration [NA]
A completed clinical trial evaluated whether lutein supplementation affects macular pigment optical density and visual acuity in patients wi…
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CLINICAL_TRIALS trial_result · 2014-11-14Clinical Trial Update: The Effect of a Single Intravitreal Anti-VEGF Therapy on Optic Nerve Head Perfusion [NA]
This ClinicalTrials.gov entry documents the termination of a study evaluating the effect of a single intravitreal anti-VEGF injection on opt…
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CLINICAL_TRIALS trial_result · 2014-11-14Clinical Trial Update: Association Between Laser Interferometric Measurement of Fundus Pulsation and Pneumotonometric Measurement of Pulsatile Ocular Blood Flow in Patients With Age-related Macular Degeneration [NA]
A completed clinical trial evaluating the relationship between laser interferometric measurements of fundus pulsation and pneumotonometric m…
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CLINICAL_TRIALS other · 2014-11-14Clinical Trial Update: Macular Pigment Optical Density in Healthy Subjects
This clinical trial update notes that the study evaluating macular pigment optical density in healthy subjects has been terminated. The tria…
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CLINICAL_TRIALS trial_result · 2014-10-29Clinical Trial Update: On-label tReatment With Intravitreal Aflibercept injectiOn for Patients With Persistent Pigment epitheliaL Detachments in Neovascular Age Related Macular Degeneration (AMD) [Phase 4]
Phase 4 clinical trial update evaluating on-label intravitreal aflibercept injections for persistent pigment epithelial detachments in neova…
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CLINICAL_TRIALS trial_result · 2014-10-23Clinical Trial Update: Study of the Macular Pigment by the Consumption of Corn With Strong Content in Zeaxanthine [NA]
Completed trial evaluating whether consuming corn with high zeaxanthin content affects macular pigment in age-related macular degeneration.
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CLINICAL_TRIALS trial_result · 2014-10-20Clinical Trial Update: 20089 TA+Lucentis Combo Intravitreal Injections for Treatment of Neovascular Age-related Macular Degeneration (AMD) [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating intravitreal injections combining triamcinolone acetonide with ranibizumab (Lucentis) for neovascular …
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CLINICAL_TRIALS trial_result · 2014-10-15Clinical Trial Update: Drusen Morphology Changes in Nonexudative Age-related Degeneration After Oral Antioxidants Supplementation [NA]
A completed clinical trial evaluating whether oral antioxidant supplementation affects drusen morphology in nonexudative age-related macular…
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CLINICAL_TRIALS trial_result · 2014-10-03Clinical Trial Update: Home Vision Monitoring Using the ForeseeHome Device Following Treatment of Neovascular Age Related Macular Degeneration
This clinical trial update reports the completion of a study evaluating the ForeseeHome home vision monitoring device after treatment of neo…
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CLINICAL_TRIALS trial_result · 2014-10-03Clinical Trial Update: Correlation Between Visual Field Defects on FORESEE HOME and on Optical Coherence Tomography in Choroidal Neovascularization Subjects
A clinical trial update examining the correlation between visual field defects detected by the FORESEE HOME device and optical coherence tom…
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CLINICAL_TRIALS trial_result · 2014-10-01Clinical Trial Update: Study to Assess the EffectiVeness of exIsting Anti-vascular Endothelial groWth Factor (Anti-VEGF) Treatment Regimens in Patients With Wet Age-related Macular Degeneration
This completed clinical trial evaluated the effectiveness of existing anti-VEGF treatment regimens in patients with wet age-related macular …
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CLINICAL_TRIALS trial_result · 2014-09-04Clinical Trial Update: Comparison of Phase-variance Optical Coherence Tomography and Fluorescein Angiography in Retinovascular Imaging
A UCSF-sponsored trial comparing phase-variance Optical Coherence Tomography to Fluorescein Angiography for retinovascular imaging has been …
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CLINICAL_TRIALS trial_result · 2014-08-29Clinical Trial Update: Effects of Lutein and Zeaxanthin Supplementation on Early Age-related Macular Degeneration [NA]
Clinical trial completed to assess the effects of lutein and zeaxanthin supplementation on early age-related macular degeneration. Results w…
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CLINICAL_TRIALS trial_result · 2014-07-22Clinical Trial Update: An Open, Single-center, Safety and Efficacy Study of Conbercept in Patients With Very Low Vision Secondary to Wet Age-related Macular Degeneration (wAMD) [Phase 2]
This open, single-center Phase 2 trial evaluates the safety and efficacy of Conbercept in patients with very low vision due to wet age-relat…
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CLINICAL_TRIALS trial_result · 2014-07-18Clinical Trial Update: WALTZ - Wet Age-Related Macular Degeneration (AMD) AL-39324 Treatment Examination [Phase 2]
This document reports a Phase 2 study update for AL-39324 in wet age-related macular degeneration, and notes that the trial has completed.
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CLINICAL_TRIALS trial_result · 2014-07-08Clinical Trial Update: Treatment of Diabetic Macular Edema With 0.5mg Intraocular Ranibizumab (Lucentis) [NA]
A completed clinical trial evaluated 0.5 mg intraocular ranibizumab (Lucentis) for diabetic macular edema.
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CLINICAL_TRIALS trial_result · 2014-07-03Clinical Trial Update: Geographic Atrophy Treatment Evaluation [Phase 3]
A Phase 3 trial evaluating a treatment for geographic atrophy associated with age-related macular degeneration conducted by Alcon was termin…
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CLINICAL_TRIALS trial_result · 2014-07-01Clinical Trial Update: Phase 3 Study to Evaluate Anecortave Acetate vs. Visudyne for the Treatment of the Wet Form of AMD [Phase 3]
A Phase 3 trial comparing Anecortave Acetate to Visudyne for wet age-related macular degeneration has completed.
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CLINICAL_TRIALS trial_result · 2014-06-25Clinical Trial Update: Ziv-aflibercept in Eyes With Retinal Diseases and Poor Vision-phase I [Phase 1]
Phase I clinical trial of Ziv-aflibercept for retinal diseases, including age-related macular degeneration and central retinal vein occlusio…