Age-related Macular Degeneration
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2016-08-30Clinical Trial Update: Association of Previously Verified Gene Polymorphisms With AMD in Turkish Population
This clinical trial update reports on a study examining whether previously verified gene polymorphisms are associated with age-related macul…
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CLINICAL_TRIALS trial_result · 2016-08-12Clinical Trial Update: Comparison of PDT Combination With Ranibizumab vs. Ranibizumab Monotherapy in Persistent PCV With Initial Loading Dose [Phase 4]
Phase 4 clinical trial update comparing photodynamic therapy plus ranibizumab versus ranibizumab alone in persistent polypoidal choroidal va…
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CLINICAL_TRIALS withdrawal · 2016-08-08Clinical Trial Update: Subretinal Lucentis for Hemorrhagic Age-related Macular Degeneration (AMD) [Phase 1]
A Phase 1 trial evaluating subretinal Lucentis (ranibizumab) for hemorrhagic age-related macular degeneration has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-07-06Clinical Trial Update: Development of a Device to Measure Dark Adaptation
This clinical trial update reports the completion of a study evaluating a device that measures dark adaptation in individuals with age-relat…
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CLINICAL_TRIALS trial_result · 2016-06-02Clinical Trial Update: Study of HUCNS-SC Subretinal Transplantation in Subjects With GA of AMD [Phase 2]
Phase 2 study of HUCNS-SC subretinal transplantation for geographic atrophy in age-related macular degeneration has been terminated.
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CLINICAL_TRIALS trial_result · 2016-06-02Clinical Trial Update: Long-Term Follow-up Safety Study of Human Central Nervous System Stem Cells in Subjects With Geographic Atrophy of Age-Related Macular Degeneration
Long-term follow-up safety study of human central nervous system stem cells in geographic atrophy due to age-related macular degeneration ha…
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CLINICAL_TRIALS safety_alert · 2016-06-01Clinical Trial Update: Resistance to Antibiotics in Patients Receiving Eye Injections
The document reports concerns about antibiotic resistance in patients receiving intraocular eye injections, which could impact treatment str…
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CLINICAL_TRIALS research · 2016-06-01Clinical Trial Update: Treatment of AMD With Rheohemapheresis /RHF/ [Phase 4]
Phase 4 clinical trial update evaluating rheohemapheresis for age-related macular degeneration; current status of the study is unknown.
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CLINICAL_TRIALS trial_result · 2016-05-19Clinical Trial Update: Systemic Pharmacokinetics Following Intravitreal Injections of Anti-VEGF [Phase 1, Phase 2]
A Phase 1/2 clinical trial update reports systemic pharmacokinetics after intravitreal injections of an anti-VEGF agent.
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FDA approval · 2016-05-11FDA Approved: VISUDYNE — Supplemental Application (Bausch & Lomb Incorporated)
The FDA approved a supplemental application for VISUDYNE (verteporfin for injection) from Bausch & Lomb Incorporated.
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CLINICAL_TRIALS trial_result · 2016-05-11Clinical Trial Update: Safety Study of PF582 Versus Lucentis in Patients With Age Related Macular Degeneration [Phase 1, Phase 2]
Clinical trial update indicating completion of a Phase 1/2 safety study comparing PF582 with Lucentis in age-related macular degeneration.
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CLINICAL_TRIALS trial_result · 2016-04-29Clinical Trial Update: Effect of Intravitreal VEGF-Trap Eye on Polypoidal Choroidal Vasculopathy [Phase 4]
Phase 4 trial evaluating intravitreal VEGF Trap-Eye (aflibercept) for polypoidal choroidal vasculopathy and exudative age-related macular de…
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CLINICAL_TRIALS trial_result · 2016-04-20Clinical Trial Update: Bevacizumab in Combination With Visudyne Photodynamic Therapy (PDT) [Phase 2]
This Phase 2 trial assessing bevacizumab in combination with Visudyne photodynamic therapy for age-related macular degeneration and related …
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CLINICAL_TRIALS trial_result · 2016-04-06Clinical Trial Update: Triple Combination Therapy of Choroidal Neovascularization in AMD, a Cost Effect and Efficient Therapeutic Treatment
This completed clinical trial evaluated a triple combination therapy for choroidal neovascularization in exudative age-related macular degen…
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CLINICAL_TRIALS trial_result · 2016-04-05Clinical Trial Update: A Study of Abicipar Pegol in Patients With Neovascular Age-related Macular Degeneration [Phase 2]
Phase 2 trial update evaluating Abicipar Pegol for neovascular age-related macular degeneration. The study is completed and results were pos…
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CLINICAL_TRIALS withdrawal · 2016-03-29Clinical Trial Update: HiPED - High Dose Lucentis for Persistent Pigment Epithelial Detachments in Age-related Macular Degeneration [Phase 2]
The Phase 2 HiPED trial evaluating high-dose ranibizumab (Lucentis) for persistent pigment epithelial detachments in age-related macular deg…
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CLINICAL_TRIALS trial_result · 2016-03-25Clinical Trial Update: Pharmacokinetics of CLG561 in Patients With Advanced Age-Related Macular Degeneration [Phase 1]
Phase 1 pharmacokinetics study update for CLG561 in patients with age-related macular degeneration; results from the completed trial are rep…
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CLINICAL_TRIALS trial_result · 2016-03-21Clinical Trial Update: Use of Immune Globulin Intravenous (Human) To Treat Age-Related Macular Degeneration [Phase 2]
Phase 2 trial evaluating intravenous immune globulin for age-related macular degeneration; results were posted in 2016.
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CLINICAL_TRIALS research · 2016-03-17Clinical Trial Update: Evaluation of Wet Age-Related Macular Degeneration (AMD) Genetic Profile Interactions With Ranibizumab Treatment Outcomes [NA]
This is a ClinicalTrials.gov update about a study evaluating how genetic profiles interact with ranibizumab treatment outcomes in wet age-re…
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CLINICAL_TRIALS trial_result · 2016-03-16Clinical Trial Update: Efficacy, Safety And Tolerability Study Of RN6G In Subjects With Geographic Atrophy Secondary to Age-related Macular Degeneration [Phase 2]
Phase 2 trial evaluating the efficacy, safety, and tolerability of RN6G in geographic atrophy associated with age-related macular degenerati…
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CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: Safety and Tolerability of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization Secondary to Age-related Macular Degeneration [Phase 4]
Phase 4 safety and tolerability update of ranibizumab in patients with subfoveal choroidal neovascularization secondary to age-related macul…
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CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: Lucentis Utilizing Visudyne (LUV Trial) Combination Therapy in the Treatment of Age-Related Macular Degeneration [Phase 4]
A Phase 4 trial evaluating the combination of Lucentis (ranibizumab) and Visudyne (verteporfin) for age-related macular degeneration was ter…
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CLINICAL_TRIALS trial_result · 2016-02-26Clinical Trial Update: Photodynamic Therapy Alone Versus Combined With Intravitreal Bevacizumab for Age-related Macular Degeneration [NA]
A completed clinical trial compared photodynamic therapy alone to photodynamic therapy combined with intravitreal bevacizumab for age-relate…
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CLINICAL_TRIALS trial_result · 2016-02-24Clinical Trial Update: Assessment of Scan Quality of Sparse OCT Retina Scanner (MimoStudy01) [NA]
A completed clinical trial (NCT02555995) evaluating the scan quality of the Sparse OCT Retina Scanner (MimoStudy01) for macular degeneration…
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CLINICAL_TRIALS trial_result · 2016-02-09Clinical Trial Update: Efficacy and Safety Study of ESBA1008 Versus EYLEA® [Phase 2]
Phase 2 efficacy and safety trial comparing ESBA1008 to EYLEA in exudative age-related macular degeneration has completed with results poste…