Age-related Macular Degeneration
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-02-01Clinical Trial Update: Evaluation of Oral Minocycline in the Treatment of Geographic Atrophy Associated With Age-Related Macular Degeneration [Phase 2]
Phase 2 trial results update evaluating oral minocycline for geographic atrophy in age-related macular degeneration.
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CLINICAL_TRIALS withdrawal · 2024-01-31Clinical Trial Update: The Avastin vs Visudyne for Neovascular AMD Study [Phase 3]
A Phase 3 trial comparing Avastin to Visudyne for neovascular age-related macular degeneration was withdrawn.
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Study to Assess the Efficacy and Safety of Brolucizumab 6mg Compared to Aflibercept 2 mg in a Treat-to-control Regimen (TALON) [Phase 3]
A Phase 3 TALON study comparing brolucizumab 6 mg to aflibercept 2 mg in a treat-to-control regimen for age-related macular degeneration has…
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CLINICAL_TRIALS trial_result · 2024-01-22Clinical Trial Update: Clinical Evaluation of VeriSee AMD in Screening for Age-Related Macular Degeneration
A completed clinical trial evaluating VeriSee AMD for screening age-related macular degeneration; results posted in 2024.
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CLINICAL_TRIALS trial_result · 2023-12-28Clinical Trial Update: A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor) [Phase 3]
Phase 3 safety and efficacy study of intravitreal Zimura (avacincaptad pegol) for geographic atrophy and age-related macular degeneration ha…
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CLINICAL_TRIALS trial_result · 2023-11-13Clinical Trial Update: Comparing the Efficacy and Safety of Biosimilar Candidate Xlucane Versus Lucentis® in Patients With nAMD [Phase 3]
Phase 3 trial comparing biosimilar Xlucane to Lucentis in neovascular age-related macular degeneration has completed; results posted.
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CLINICAL_TRIALS trial_result · 2023-10-23Clinical Trial Update: Evaluate the Safety and Efficacy of HLX04-O in Subjects With wAMD [Phase 1, Phase 2]
Clinical trial update for HLX04-O in subjects with age-related macular degeneration across Phase 1 and Phase 2 completed.
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CLINICAL_TRIALS trial_result · 2023-10-17Clinical Trial Update: ReCLAIM-2 Study to Evaluate Safety,Efficacy & Pharmacokinetics of Elamipretide in Subjects With AMD With Non-central GA [Phase 2]
Phase 2 trial results update for elamipretide in age-related macular degeneration with non-central geographic atrophy.
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CLINICAL_TRIALS trial_result · 2023-10-16Clinical Trial Update: A Study Assessing the Long-Term Safety and Tolerability of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration [Phase 2]
Phase 2 long-term safety and tolerability study of Galegenimab (FHTR2163) in geographic atrophy due to age-related macular degeneration has …
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FDA approval · 2023-09-28FDA Approved: BEOVU — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for BEOVU (brolucizumab) from Novartis, indicating a regulatory action that may involve labeling upd…
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CLINICAL_TRIALS trial_result · 2023-09-15Clinical Trial Update: A Study to Test How Well Different Doses of BI 754132 Are Tolerated in Patients With an Advanced Form of Age-related Macular Degeneration Called Geographic Atrophy [Phase 1]
Phase 1 study evaluating tolerability of different doses of BI 754132 in geographic atrophy due to age-related macular degeneration; trial t…
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CLINICAL_TRIALS trial_result · 2023-09-13Clinical Trial Update: Efficacy, Safety, pharmacokinetiсs, Immunogenicity of GNR-067 and Lucentis® [Phase 3]
Phase 3 trial update evaluating efficacy, safety, pharmacokinetics, and immunogenicity of GNR-067 in Age Related Macular Degeneration (ARMD)…
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CLINICAL_TRIALS trial_result · 2023-08-30Clinical Trial Update: Adjunct Episcleral Brachytherapy for PCV [Phase 3]
Phase 3 clinical trial update for adjunct episcleral brachytherapy in polypoidal choroidal vasculopathy and age-related macular degeneration…
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CLINICAL_TRIALS trial_result · 2023-07-06Clinical Trial Update: A Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration [Phase 3]
Phase 3 trial comparing intravitreal APL-2 therapy to sham injections in geographic atrophy due to age-related macular degeneration has comp…
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CLINICAL_TRIALS trial_result · 2023-06-18Clinical Trial Update: Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration [Phase 3]
Phase 3 trial comparing intravitreal APL-2 vs sham injections in geographic atrophy due to age-related macular degeneration has completed wi…
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FDA approval · 2023-06-16FDA Approved: BYOOVIZ — Supplemental Application (BIOGEN INC.)
FDA approved a supplemental application for BYOOVIZ (ranibizumab-nuna) from Biogen Inc.
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CLINICAL_TRIALS trial_result · 2023-06-09Clinical Trial Update: Metformin for the Minimization of Geographic Atrophy Progression in Patients With AMD [Phase 2]
Phase 2 trial evaluating metformin to slow geographic atrophy progression in age-related macular degeneration has completed with posted resu…
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CLINICAL_TRIALS trial_result · 2023-06-08Clinical Trial Update: A Phase II Study of RBM-007 Alone and RBM-007 With Eylea® in Subjects With Wet Age-related Macular Degeneration [Phase 2]
Phase II study assessing RBM-007 alone and with Eylea in wet age-related macular degeneration has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-06-07Clinical Trial Update: Safety and Exploratory Efficacy Study of SF0166 in the Treatment of Neovascular Age-Related Macular Degeneration (AMD) [Phase 1, Phase 2]
Phase 1/2 safety and exploratory efficacy study of SF0166 for neovascular age-related macular degeneration has completed with results posted…
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CLINICAL_TRIALS trial_result · 2023-04-12Clinical Trial Update: RBM-007 in Treatment naïve Exudative Age-related Macular Degeneration [Phase 1, Phase 2]
A Phase 1/2 clinical trial update for RBM-007 in treatment-naïve exudative age-related macular degeneration has completed, with results post…
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CLINICAL_TRIALS trial_result · 2023-03-06Clinical Trial Update: Safety and Efficacy Study of OpRegen for Treatment of Advanced Dry-Form Age-Related Macular Degeneration [Phase 1, Phase 2]
This clinical trial update reports safety and efficacy results for OpRegen in advanced dry age-related macular degeneration from a Phase 1/2…
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FDA approval · 2023-02-17FDA Approved: SYFOVRE — Original Application (Apellis Pharmaceuticals, Inc.)
FDA approved SYFOVRE (pegcetacoplan) from Apellis Pharmaceuticals for geographic atrophy associated with age-related macular degeneration, m…
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CLINICAL_TRIALS trial_result · 2023-02-14Clinical Trial Update: Efficacy and Safety of Aflibercept in Patients With Neovascular Age-related Macular Degeneration [Phase 3]
Phase 3 trial update on aflibercept for neovascular age-related macular degeneration assessing efficacy and safety.
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CLINICAL_TRIALS trial_result · 2023-01-31Clinical Trial Update: Transpalpebral Microcurrent Stimulation for the Improvement of Visual Acuity in Patients With Macular Degeneration [Phase 1, Phase 2]
Clinical trial update reports completion of Phase 1 and Phase 2 studies evaluating transpalpebral microcurrent stimulation to improve visual…
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CLINICAL_TRIALS research · 2023-01-26Clinical Trial Update: FLIO and the Influence of Oral Lutein Supplementation on Macular Pigment [Phase 4]
Phase 4 trial update evaluating whether oral lutein supplementation influences macular pigment in age-related macular degeneration.