Age-related Macular Degeneration

CLINICAL_TRIALS trial_result · 2020-10-09

Clinical Trial Update: A Proof-of-Concept Study of Faricimab (RO6867461) in Participants With Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD) [Phase 2]

Phase 2 proof-of-concept trial of faricimab in choroidal neovascularization due to age-related macular degeneration has completed with resul…

CLINICAL_TRIALS trial_result · 2020-10-01

Clinical Trial Update: A Study to Compare LY09004 and Eylea in the Treatment of Wet Age-related Macular Degeneration（wAMD） [Phase 3]

Phase 3 clinical trial comparing LY09004 with Eylea for wet age-related macular degeneration.

CLINICAL_TRIALS trial_result · 2020-09-30

Clinical Trial Update: A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Either Avastin® or Eylea® Compared to Avastin® or Eylea® Monotherapy [Phase 3]

Phase 3 safety and efficacy study of Fovista in combination with Avastin or Eylea for age-related macular degeneration was terminated with r…

CLINICAL_TRIALS trial_result · 2020-09-24

Clinical Trial Update: Study Evaluating Intravitreal hI-con1™ in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration [Phase 2]

Phase 2 trial evaluating intravitreal hI-con1 for choroidal neovascularization due to age-related macular degeneration has completed with po…

CLINICAL_TRIALS trial_result · 2020-09-21

Clinical Trial Update: An Open-Label, Phase 1 Clinical Study to Evaluate the Safety and Tolerability of Subcutaneous Elamipretide in Subjects With Intermediate Age-Related Macular Degeneration [Phase 1]

Phase 1 open-label study evaluating safety and tolerability of subcutaneous elamipretide in intermediate age-related macular degeneration ha…

CLINICAL_TRIALS trial_result · 2020-08-13

Clinical Trial Update: Study to Collect Safety and ECG Data on Brolucizumab 6 mg Intravitreal Treatment in Patients With Wet AMD [Phase 3]

Phase 3 trial update reporting on safety and ECG data collection for brolucizumab 6 mg intravitreal treatment in wet age-related macular deg…

CLINICAL_TRIALS trial_result · 2020-08-06

Clinical Trial Update: Alpha Lipoic Acid in Geographic Atrophy [Phase 1, Phase 2]

Trial update for alpha lipoic acid in geographic atrophy as part of age-related macular degeneration; study completed with results posted.

CLINICAL_TRIALS trial_result · 2020-08-03

Clinical Trial Update: A Study to Evaluate Abicipar Pegol for Safety and Treatment Effect in Participants With Neovascular Age-related Macular Degeneration (AMD) [Phase 2]

Phase 2 trial evaluating safety and treatment effect of abicipar pegol for neovascular age-related macular degeneration has completed with r…

CLINICAL_TRIALS trial_result · 2020-07-30

Clinical Trial Update: Safety and Efficacy of Abicipar Pegol in Participants With Neovascular Age-related Macular Degeneration [Phase 3]

Phase 3 trial update on safety and efficacy of abicipar pegol in neovascular age-related macular degeneration has completed with results pos…

CLINICAL_TRIALS trial_result · 2020-07-28

Clinical Trial Update: A Safety and Efficacy Study of Abicipar Pegol in Participants With Neovascular Age-related Macular Degeneration [Phase 3]

Phase 3 trial investigating safety and efficacy of Abicipar Pegol in neovascular age-related macular degeneration has completed with results…

CLINICAL_TRIALS trial_result · 2020-06-23

Clinical Trial Update: A Study to Evaluate the Safety and Clinical Response of Subretinal Administration of CNTO 2476 in Participants With Geographic Atrophy [Phase 2]

Phase 2 trial update on subretinal administration of CNTO 2476 in geographic atrophy, reporting safety and clinical response outcomes with r…

CLINICAL_TRIALS trial_result · 2020-05-27

Clinical Trial Update: Cooling Anesthesia for Intravitreal Injection [Phase 1, Phase 2]

Clinical trial update on cooling anesthesia for intravitreal injection showing completed Phase 1 and Phase 2 studies.

CLINICAL_TRIALS trial_result · 2020-05-21

Clinical Trial Update: Managing Neovascular (Known as "Wet") Age-related Macular Degeneration Over 2 Years Using Different Treatment Schedules of 2 mg Intravitreal Aflibercept Injected in the Eye [Phase 4]

Phase 4 clinical trial evaluating 2 mg intravitreal aflibercept with different dosing schedules for wet age-related macular degeneration ove…

CLINICAL_TRIALS trial_result · 2020-05-19

Clinical Trial Update: Efficacy and Safety of "Treat-and-Extend" Regimen Versus "Pro Re Nata" of Conbercept in Age-related Macular Degeneration [Phase 4]

Phase 4 trial comparing Treat-and-Extend versus Pro Re Nata regimens of conbercept for age-related macular degeneration; efficacy and safety…

CLINICAL_TRIALS trial_result · 2020-04-01

Clinical Trial Update: Efficacy of Acupuncture in Macular Diseases [NA]

A completed clinical trial evaluating acupuncture for macular diseases (age-related macular degeneration and Stargardt disease) with results…

CLINICAL_TRIALS trial_result · 2020-03-10

Clinical Trial Update: Povidone Iodine vs AVEnova: A Pre-injection Disinfection Study (PAVE Study) [Phase 4]

Phase 4 trial comparing povidone iodine disinfection to AVEnova in pre-injection procedures for retinal diseases; completed.

CLINICAL_TRIALS trial_result · 2020-02-17

Clinical Trial Update: Subthreshold Laser Treatment for Reticular Pseudodrusen and Geographic Atrophy Secondary to AMD [NA]

Completed results for a trial of subthreshold laser treatment for reticular pseudodrusen and geographic atrophy due to age-related macular d…

CLINICAL_TRIALS trial_result · 2020-01-14

Clinical Trial Update: A Phase I/II Safety, Tolerability, Immunogenicity, and Bioactivity Study of DE-122 Injectable Solution for Refractory Exudative Age-related Macular Degeneration [Phase 1, Phase 2]

Phase I/II study assessing safety, tolerability, immunogenicity, and bioactivity of DE-122 injectable solution for refractory exudative age-…

CLINICAL_TRIALS trial_result · 2020-01-13

Clinical Trial Update: Safety and Tolerability of Oral CM082 in Patients With wAMD [Phase 2]

Phase 2 study evaluating safety and tolerability of oral CM082 in patients with age-related macular degeneration.

CLINICAL_TRIALS trial_result · 2019-12-04

Clinical Trial Update: Rod Sensitivity in Age-related Macular Degeneration (AMD) and Retinitis Pigmentosa (RP)

Clinical trial completed investigating rod sensitivity in age-related macular degeneration and retinitis pigmentosa; results posted in 2019.

CLINICAL_TRIALS trial_result · 2019-12-03

Clinical Trial Update: Dorzolamide-timolol Drops With Injections to Treat AMD, RVO or DME. [Phase 2]

Phase 2 trial evaluating dorzolamide-timolol drops administered with injections for wet AMD, age-related macular degeneration, diabetic macu…

CLINICAL_TRIALS trial_result · 2019-08-28

Clinical Trial Update: Clinical Assessment Of Age-related Macular Degeneration Patients After Early Diagnosis and Treatment With Ranibizumab [Phase 2, Phase 3]

A Phase 2/3 clinical trial evaluating ranibizumab for age-related macular degeneration was terminated with results posted in 2019.

CLINICAL_TRIALS trial_result · 2019-08-15

Clinical Trial Update: Ranibizumab In Pigment Epithelium Tears Secondary To Age-Related Macular Degeneration Study [Phase 2]

Phase 2 trial update of ranibizumab for pigment epithelium tears associated with age-related macular degeneration; study completed with resu…

CLINICAL_TRIALS trial_result · 2019-08-14

Clinical Trial Update: Study EvAluating Genotypes While Using Lucentis 2 [Phase 4]

Phase 4 trial update evaluating genotypes while using Lucentis for age-related macular degeneration; study completed with results posted in …

CLINICAL_TRIALS trial_result · 2019-07-23

Clinical Trial Update: S0000B: Vitamin E and/or Selenium in Preventing Cataract and Age-Related Macular Degeneration in Men on SELECT SWOG-S0000 [Phase 3]

Phase 3 trial evaluating vitamin E and/or selenium for preventing cataract and age-related macular degeneration in men; study completed with…

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