Age-related Macular Degeneration
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-07-22Clinical Trial Update: Study of Safety and Efficacy of Brolucizumab 6 mg Dosed Every 4 Weeks Compared to Aflibercept 2 mg Dosed Every 4 Weeks in Patients With Retinal Fluid Despite Frequent Anti-VEGF Injections [Phase 3]
Phase 3 trial comparing brolucizumab 6 mg every 4 weeks to aflibercept 2 mg every 4 weeks in patients with retinal fluid despite frequent an…
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CLINICAL_TRIALS trial_result · 2022-05-12Clinical Trial Update: Safety And Tolerability Study Of RN6G In Subjects With Advanced Dry, Age-Related Macular Degeneration Including Geographic Atrophy [Phase 1]
Phase 1 safety and tolerability study of RN6G in subjects with advanced dry age-related macular degeneration including geographic atrophy ha…
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CLINICAL_TRIALS trial_result · 2022-04-27Clinical Trial Update: Plasma Levels of Vascular Endothelial Growth Factor Before and After Intravitreal Injection of Aflibercept [Phase 4]
Phase 4 trial update evaluating plasma VEGF levels before and after intravitreal aflibercept injection in exudative age-related macular dege…
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CLINICAL_TRIALS trial_result · 2022-04-19Clinical Trial Update: SD-OCT Angiography [NA]
Clinical trial update for SD-OCT Angiography study (NCT02510885) sponsored by Duke University; the trial is terminated, with results posted …
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CLINICAL_TRIALS trial_result · 2021-09-30Clinical Trial Update: Efficacy and Safety of the Biosimilar Ranibizumab FYB201 in Comparison to Lucentis in Patients With Neovascular Age-related Macular Degeneration [Phase 3]
Phase 3 trial comparing biosimilar ranibizumab FYB201 to Lucentis in neovascular age-related macular degeneration completed with posted resu…
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CLINICAL_TRIALS trial_result · 2021-09-17Clinical Trial Update: Cataract and AMD in a Trial of a Multivitamin and Cocoa Extract [Phase 4]
Phase 4 trial update investigating a multivitamin and cocoa extract in cataract and age-related macular degeneration.
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CLINICAL_TRIALS trial_result · 2021-08-18Clinical Trial Update: An Open Label-study to Compare the Efficacy of Aflibercept Monotherapy for Polypoidal Choroidal Vasculopathy [Phase 4]
Phase 4 open-label study assessing aflibercept monotherapy for polypoidal choroidal vasculopathy, completed with posted results in 2021.
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CLINICAL_TRIALS trial_result · 2021-07-13Clinical Trial Update: Study Assessing the Efficacy and Safety of Intravitreal Injections of DE-122 in Combination With Lucentis® Compared to Lucentis® Monotherapy in Wet Age-related Macular Degeneration Subjects [Phase 2]
Phase 2 trial evaluating intravitreal DE-122 plus Lucentis versus Lucentis alone for wet age-related macular degeneration completed with pos…
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CLINICAL_TRIALS trial_result · 2021-05-21Clinical Trial Update: A Study to Compare SB11 (Proposed Ranibizumab Biosimilar) to Lucentis in Subjects With Neovascular Age-related Macular Degeneration (AMD) [Phase 3]
Phase 3 trial comparing SB11 (ranibizumab biosimilar) to Lucentis in neovascular age-related macular degeneration has completed with results…
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CLINICAL_TRIALS trial_result · 2021-05-21Clinical Trial Update: Global Atrophie Biomarker Evaluation Study (GABiE)
Global Atrophie Biomarker Evaluation Study (GABiE) terminated; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-05-19Clinical Trial Update: Non-Damaging Photothermal Therapy of Non-exudative Age Related Macular Degeneration [NA]
A completed clinical trial investigating non-damaging photothermal therapy for non-exudative age-related macular degeneration with results p…
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CLINICAL_TRIALS trial_result · 2021-05-06Clinical Trial Update: Study of the Efficacy and Safety of the Ranibizumab Port Delivery System for Sustained Delivery of Ranibizumab in Patients With Subfoveal Neovascular Age-Related Macular Degeneration [Phase 2]
Phase 2 trial evaluating the Ranibizumab Port Delivery System for sustained delivery in subfoveal neovascular age-related macular degenerati…
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CLINICAL_TRIALS trial_result · 2021-04-28Clinical Trial Update: Cytokine and Visual Outcome Variations in Eyes Receiving Aflibercept [Phase 4]
Phase 4 trial update exploring cytokine and visual outcomes in eyes treated with aflibercept for age-related macular degeneration and diabet…
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CLINICAL_TRIALS trial_result · 2021-04-28Clinical Trial Update: Cytokine and Visual Outcome Variations in Eyes Receiving Ranibizumab [Phase 4]
Phase 4 trial exploring how cytokine changes relate to visual outcomes in eyes treated with ranibizumab for macular diseases.
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CLINICAL_TRIALS trial_result · 2021-04-20Clinical Trial Update: A Study to Assess the Safety, Tolerability and Effectiveness of MT-0814 for the Treatment of Age-related Macular Degeneration [Phase 2]
Phase 2 trial assessing MT-0814 for age-related macular degeneration was terminated; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-03-25Clinical Trial Update: EAGLE: Evaluating Genotypes Using Intravitreal Aflibercept Injection [Phase 4]
Phase 4 trial evaluating genotypes using intravitreal aflibercept in macular degeneration has completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-03-15Clinical Trial Update: Open-Label Study of Intravitreal ICON-1 in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration (AMD) [Phase 2]
Phase 2 open-label study of intravitreal ICON-1 in choroidal neovascularization due to age-related macular degeneration has been terminated …
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CLINICAL_TRIALS trial_result · 2021-01-28Clinical Trial Update: PRedictive Factors and Changes From Treatment in iPCV Versus CSR Versus nAMD With afLibercept [Phase 4]
Phase 4 trial update evaluating predictive factors and treatment changes among af Libercept regimens for central serous chorioretinopathy an…
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CLINICAL_TRIALS trial_result · 2021-01-05Clinical Trial Update: RBM-007 in Subjects witH ExudatIve Age-related Macular Degeneration [Phase 1, Phase 2]
Clinical trials update for RBM-007 in age-related macular degeneration (Phase 1/2) completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-01-05Clinical Trial Update: Visual Enhancement Device in Low Vision Patients [NA]
Clinical trial update for a visual enhancement device in low vision patients has terminated; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2020-12-30Clinical Trial Update: BEOVU in the Treatment of Dystrophy-related Macular Neovascular Degeneration [Phase 4]
Phase 4 clinical trial update for BEOVU addressing dystrophy-related macular neovascular degeneration.
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CLINICAL_TRIALS trial_result · 2020-10-28Clinical Trial Update: Safety and Clinical Effectiveness of Intravitreal Bevacizumab (Lumiere®) in Patients With Wet Age-related Macular Degeneration (Wet AMD) [Phase 3]
Phase 3 trial assessing safety and clinical effectiveness of intravitreal bevacizumab (Lumiere) for wet age-related macular degeneration.
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CLINICAL_TRIALS trial_result · 2020-10-22Clinical Trial Update: Efficacy and Safety of Lucentis® Use in Patients With Diabetic Macular Edema Evaluating a Spaced Out Follow-up After Intensive Treatment Phase [Phase 3]
A Phase 3 clinical trial update on Lucentis (ranibizumab) assessing efficacy and safety in diabetic macular edema and related macular condit…
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CLINICAL_TRIALS trial_result · 2020-10-22Clinical Trial Update: Efficacy of Biweekly Ranibizumab (0.5 mg) for Exudative Macular Degeneration Retinal Edema Refractory to Anti-VEGF [Phase 2]
Phase 2 trial evaluating biweekly ranibizumab (0.5 mg) for exudative age-related macular degeneration with retinal edema unresponsive to ant…
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CLINICAL_TRIALS trial_result · 2020-10-14Clinical Trial Update: Extension Study to Gather Data on Effect of Macugen on the Corneal Endothelium [Phase 4]
A Phase 4 extension study assessing the effect of Macugen on the corneal endothelium has completed, with results posted in 2020.