Age-related Macular Degeneration
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: A Long-Term Monitoring Study of the IMT-002 Patients [NA]
This update reports long-term monitoring outcomes for patients treated with IMT-002 for age-related macular degeneration, and the study stat…
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CLINICAL_TRIALS trial_result · 2017-11-01Clinical Trial Update: The Potential Role of Dietary Antioxidant Capacity on Age-Related Macular Degeneration
This clinical trial update notes that the study examining the potential role of dietary antioxidant capacity in age-related macular degenera…
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CLINICAL_TRIALS trial_result · 2017-10-27Clinical Trial Update: Short-term Clinical Effects of Intravitreal Aflibercept Injection 2.0mg as a Predictor of Long-term Results [Phase 4]
Phase 4 clinical trial update evaluating short-term effects of intravitreal aflibercept 2.0 mg as a predictor of long-term outcomes in age-r…
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CLINICAL_TRIALS trial_result · 2017-10-20Clinical Trial Update: Treat & Extend Treatment With 0.5mg Ranibizumab vs Monthly Treatment With 0.5mg Ranibizumab [Phase 3]
Phase 3 trial comparing treat-and-extend with 0.5 mg ranibizumab versus monthly 0.5 mg ranibizumab for macular degeneration; trial completed…
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CLINICAL_TRIALS trial_result · 2017-10-19Clinical Trial Update: Effect of Aflibercept on Human Corneal Endothelial Cells in Neovascular Age-Related Macular Degeneration
A completed clinical trial evaluated the effects of aflibercept on human corneal endothelial cells in neovascular age-related macular degene…
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CLINICAL_TRIALS trial_result · 2017-10-09Clinical Trial Update: The Safety and Tolerability of Sub-retinal Transplantation of SCNT-hES-RPE Cells in Patients With Advanced Dry AMD [Phase 1]
Phase 1 trial evaluating the safety and tolerability of sub-retinal transplantation of SCNT-hES-derived retinal pigment epithelium (RPE) cel…
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CLINICAL_TRIALS trial_result · 2017-10-06Clinical Trial Update: A Pilot Study to Evaluate the Role of High-dose Ranibizumab (2.0mg) in the Management of AMD in Patients With Persistent/Recurrent Macular Fluid Less Than 30 Days Following Treatment With Intravitreal Anti-VEGF Therapy (the LAST Study) [Phase 1, Phase 2]
Pilot Phase 1/2 study evaluating high-dose ranibizumab (2.0 mg) for persistent or recurrent macular fluid in age-related macular degeneratio…
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CLINICAL_TRIALS trial_result · 2017-09-29Clinical Trial Update: Safety and Pharmacokinetics of RTH258 in Subjects With Age-Related Macular Degeneration [Phase 2]
This Phase 2 trial update summarizes safety and pharmacokinetics data for RTH258 (brolucizumab) in subjects with neovascular age-related mac…
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CLINICAL_TRIALS trial_result · 2017-09-01Clinical Trial Update: Safety and Efficacy Study of rAAV.sFlt-1 in Patients With Exudative Age-Related Macular Degeneration [Phase 1, Phase 2]
A completed Phase 1/2 trial assessing the safety and efficacy of rAAV.sFlt-1 gene therapy in patients with exudative age-related macular deg…
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CLINICAL_TRIALS trial_result · 2017-08-21Clinical Trial Update: 12 Week Patient Study in Neovascular Age-related Macular Degeneration (AMD) [Phase 2]
Phase 2 clinical trial update for neovascular age-related macular degeneration; the study was terminated with results posted.
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CLINICAL_TRIALS trial_result · 2017-08-08Clinical Trial Update: A Safety Study of CNTO 2476 in Patients With Age-Related Macular Degeneration [Phase 1, Phase 2]
This clinical trial update reports the completion of a Phase 1/2 safety study evaluating CNTO 2476 in age-related macular degeneration.
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CLINICAL_TRIALS trial_result · 2017-07-28Clinical Trial Update: Ocular Discomfort Assessment After Intravitreal Injections [NA]
This completed clinical trial update reports measurements of ocular discomfort after intravitreal injections. The findings may inform the sa…
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CLINICAL_TRIALS trial_result · 2017-07-25Clinical Trial Update: 30g vs 33g Needle for Intravitreal Injections [NA]
This completed clinical trial compared 30-gauge versus 33-gauge needles for intravitreal injections in patients with age-related macular deg…
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CLINICAL_TRIALS trial_result · 2017-07-21Clinical Trial Update: Intravitreal Bone Marrow-Derived Stem Cells in Patients With Macular Degeneration [NA]
This clinical trial evaluated intravitreal bone marrow-derived stem cell therapy in patients with age-related macular degeneration and Starg…
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CLINICAL_TRIALS trial_result · 2017-07-19Clinical Trial Update: Pars Plana Vitrecromy in Patients Aged 85 Years and Above
A clinical trial update reports on pars plana vitrectomy in patients aged 85 and older, including indications such as vitreous disorders, re…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Metabolic Mapping to Measure Retinal Metabolism [Phase 2]
Phase 2 clinical trial update from the National Eye Institute on metabolic mapping to measure retinal metabolism in macular degeneration and…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Detection of Neutralizing Antibodies in Patients Treated With Bevacizumab or Ranibizumab
This trial update reports detection of neutralizing antibodies in patients treated with bevacizumab or ranibizumab for age-related macular d…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Effect of DHA Supplements on Macular Function in Patients With Stargardt Macular Dystrophy and Stargardt-like Macular Dystrophy [Phase 1]
Phase 1 trial evaluating whether DHA supplements improve macular function in patients with Stargardt disease and Stargardt-like macular dyst…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Identification and Treatment of Feeder Vessels in Macular Degeneration [Phase 1]
Phase 1 trial update on identifying and treating feeder vessels in age-related macular degeneration; the study status is completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Intravitreal v. Sub-tenon Injections of Triamcinolone Acetonide for Macular Edema in Retinal Disorders [Phase 1]
A Phase 1 trial comparing intravitreal and sub-tenon injections of Triamcinolone acetonide for macular edema in retinal disorders has comple…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Retinal and Retinal Pigment Epithelium (RPE) Autoimmunity in Age-related Macular Degeneration (AMD) [Phase 2]
A Phase 2 trial evaluating retinal pigment epithelium autoimmunity in age-related macular degeneration has completed, with results posted in…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Eye Injections of Triamcinolone Acetonide for Retinal Blood Vessel Disorders [Phase 1]
NEI-sponsored Phase 1 trial evaluated intravitreal injections of Triamcinolone Acetonide for age-related macular degeneration and retinal ve…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Triamcinolone Acetonide Plus Laser Therapy to Treat Age-Related Macular Degeneration [Phase 3]
A Phase 3 trial evaluating Triamcinolone Acetonide in combination with laser therapy for age-related macular degeneration has completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Lutein/Zeaxanthin and Omega-3 Supplementation in Persons Over Age 60 [Phase 1]
Phase 1 trial assessing lutein, zeaxanthin, and omega-3 supplementation in people over 60 with macular degeneration has completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Screening for Studies on Retinovascular Diseases
This update reports that screening for studies on retinovascular diseases sponsored by the National Eye Institute has completed, covering di…