Adrenomyeloneuropathy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-26Clinical Trial Results: A Study to Evaluate Administration of SBT101 Gene Therapy in Adult Patients With Adrenomyeloneuropathy (AMN) [Phase 1, Phase 2]
Phase 1/2 study evaluating SBT101 gene therapy in adult adrenomyeloneuropathy (AMN) has been terminated; results posted.
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CLINICAL_TRIALS trial_result · 2025-10-31Clinical Trial Update: A Study to Evaluate Administration of SBT101 Gene Therapy in Adult Patients With Adrenomyeloneuropathy (AMN) [Phase 1, Phase 2]
A Phase 1/2 study evaluating the SBT101 gene therapy for Adrenomyeloneuropathy (a form of X-linked adrenoleukodystrophy) has been terminated…
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CLINICAL_TRIALS trial_result · 2025-10-30Clinical Trial Update: Study of Disease Progression in Adults With Inherited Forms of Spastic Paraplegia
A SwanBio Therapeutics study on disease progression in adults with inherited forms of spastic paraplegia has been terminated, involving Adre…
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CLINICAL_TRIALS trial_result · 2025-03-18Clinical Trial Update: A Clinical Study to Evaluate the Efficacy and Safety of MIN-102 (IMP) in Male AMN Patients. [Phase 2, Phase 3]
The clinical trial update indicates completion of Phase 2 and Phase 3 studies evaluating MIN-102 for efficacy and safety in male patients wi…
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CLINICAL_TRIALS research · 2025-03-10Clinical Trial Update: Home Exercise for Individuals with Neurodegenerative Disease [NA]
A clinical trial update for a home-based exercise program targeting individuals with neurodegenerative diseases, including leukodystrophy, a…
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: A Study to Assess the Pharmacodynamics of VK0214 in Male Subjects With AMN [Phase 1]
A Phase 1 pharmacodynamics study of VK0214 in male subjects with adrenomyeloneuropathy (AMN) associated with X-linked adrenoleukodystrophy (…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Epidural Spinal Cord Stimulation for Lower-limb Impairment in Adrenomyeloneuropathy [NA]
This document notes a clinical trial evaluating epidural spinal cord stimulation to improve lower-limb impairment in patients with adrenomye…
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CLINICAL_TRIALS withdrawal · 2024-12-16Clinical Trial Update: Study to Assess PXL065 in Subjects With Adrenomyeloneuropathy (AMN) Form of X-linked Adrenoleukodystrophy (X-ALD or ALD) [Phase 2]
Phase 2 trial of PXL065 for adrenomyeloneuropathy (AMN), a form of X-linked adrenoleukodystrophy, has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-12-16Clinical Trial Update: Study to Assess PXL770 in Subjects With Adrenomyeloneuropathy (AMN) Form of X-linked Adrenoleukodystrophy (X-ALD or ALD) [Phase 2]
A Phase 2 clinical trial evaluating PXL770 for Adrenomyeloneuropathy (AMN), a form of X-linked adrenoleukodystrophy, has been withdrawn.
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CLINICAL_TRIALS research · 2024-07-25Clinical Trial Update: Dimethyl Fumarate in Adrenomyeloneuropathy [Phase 2, Phase 3]
Clinical trial update indicating dimethyl fumarate is being tested for adrenomyeloneuropathy without cerebral involvement, currently recruit…
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CLINICAL_TRIALS trial_result · 2022-09-22Clinical Trial Update: Plasma Exchange With Albumin in AMN Patients [Phase 2, Phase 3]
A Phase 2/Phase 3 trial evaluating plasma exchange with albumin in patients with Adrenomyeloneuropathy and Adrenoleukodystrophy has complete…
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CLINICAL_TRIALS trial_result · 2021-09-27Clinical Trial Update: Repetitive Transcranial Magnetic Stimulation as Therapy in Hereditary Spastic Paraplegia and Adrenomyeloneuropathy [NA]
A completed clinical trial investigating repetitive transcranial magnetic stimulation as a therapy for hereditary spastic paraplegia and adr…
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CLINICAL_TRIALS trial_result · 2019-09-10Clinical Trial Update: Effect of Pioglitazone Administered to Patients With Adrenomyeloneuropathy [Phase 2]
Phase 2 trial update on pioglitazone in patients with adrenomyeloneuropathy and X-linked adrenoleukodystrophy has completed.
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CLINICAL_TRIALS trial_result · 2019-03-11Clinical Trial Update: A Clinical Trial for AMN: Validation of Biomarkers of Oxidative Stress, Efficacy and Safety of a Mixture of Antioxidants [Phase 2]
Phase 2 trial evaluating a mixture of antioxidants for adrenomyeloneuropathy has completed.
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CLINICAL_TRIALS trial_result · 2017-10-09Clinical Trial Update: MD1003-AMN MD1003 in Adrenomyeloneuropathy [Phase 2, Phase 3]
Clinical trial MD1003 for Adrenomyeloneuropathy and Adrenoleukodystrophy has completed Phase 2/Phase 3.
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CLINICAL_TRIALS withdrawal · 2014-02-14Clinical Trial Update: Safety and Pharmacodynamic Study of Sobetirome in X-Linked Adrenoleukodystrophy (X-ALD) [Phase 1]
Phase 1 safety and pharmacodynamic study of sobetirome in X-linked adrenoleukodystrophy has been withdrawn.
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CLINICAL_TRIALS trial_result · 2012-03-02Clinical Trial Update: A Phase III Trial of Lorenzo's Oil in Adrenomyeloneuropathy [Phase 3]
Phase III trial of Lorenzo's Oil for adrenomyeloneuropathy and adrenoleukodystrophy has been terminated.
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CLINICAL_TRIALS trial_result · 2011-08-10Clinical Trial Update: The Effect of Bezafibrate on the Level of Very Long Chain Fatty Acids (VLCFA) in X-linked Adrenoleukodystrophy (X-ALD) [NA]
Completed clinical trial evaluating the effect of bezafibrate on very long chain fatty acid (VLCFA) levels in X-linked adrenoleukodystrophy …