Undifferentiated Leukemia

• CLINICAL_TRIALS trial_result · 2026-04-13
  Clinical Trial Update: Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT) [Phase 1, Phase 2]

  Phase I/II trial evaluating an engineered donor graft named Orca Q for pediatric hematopoietic cell transplantation is currently suspended. …

• CLINICAL_TRIALS trial_result · 2026-04-07
  Clinical Trial Update: Prophylactic and Therapeutic DLI-X for Leukemia Relapse After HCT [Phase 1]

  Phase 1 clinical trial update on DLI-X as a prophylactic and therapeutic donor lymphocyte infusion to prevent or treat leukemia relapse afte…

• CLINICAL_TRIALS research · 2026-03-09
  Clinical Trial Update: A Phase I Study of Hyper-CVAD In Combination With Venetoclax In Pediatric Patients With Relapsed or Refractory Acute Leukemias That Are of the Lymphoid Lineage Including Bi-Phenotypic or Undifferentiated Leukemias [Phase 1]

  A Phase I pediatric trial evaluating Hyper-CVAD in combination with venetoclax for relapsed or refractory acute leukemias of the lymphoid li…

• CLINICAL_TRIALS withdrawal · 2026-02-24
  Clinical Trial Update: Cryopreserved MMUD BM With PTCy for Hematologic Malignancies [Phase 1]

  Phase 1 trial of cryopreserved MMUD bone marrow with post-transplant cyclophosphamide for hematologic malignancies has been withdrawn.

• CLINICAL_TRIALS research · 2025-11-14
  Clinical Trial Update: HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant [Phase 1]

  This clinical trial update describes a Phase 1 study evaluating HA-1 TCR T-cell immunotherapy for relapsed or refractory acute leukemia afte…

• Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
• CLINICAL_TRIALS research · 2025-11-06
  Clinical Trial Update: Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse [Phase 1, Phase 2]

  This clinical trial evaluates decitabine in combination with the FLAG-Ida chemotherapy regimen and total-body irradiation, followed by donor…

• CLINICAL_TRIALS research · 2025-10-15
  Clinical Trial Update: Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant [Phase 2]

  Phase 2 clinical trial evaluating naive T cell depletion to prevent chronic graft-versus-host disease in children and young adults receiving…

• CLINICAL_TRIALS trial_result · 2025-09-26
  Clinical Trial Update: Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies [Phase 3]

  A Phase 3 randomized trial evaluating Orca-T in allogeneic stem cell transplantation for hematologic malignancies; results have been posted.

• CLINICAL_TRIALS trial_result · 2025-08-06
  Clinical Trial Update: HLA-Mismatched Unrelated Donor Bone Marrow Transplantation With Post-Transplantation Cyclophosphamide [Phase 2]

  Phase 2 clinical trial evaluating HLA-mismatched unrelated donor bone marrow transplantation with post-transplant cyclophosphamide; the stud…

• CLINICAL_TRIALS trial_result · 2025-06-04
  Clinical Trial Update: Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD [Phase 2]

  Phase 2 clinical trial assessing selective depletion of CD45RA+ T cells from allogeneic stem cell grafts to prevent graft-versus-host diseas…

• CLINICAL_TRIALS trial_result · 2024-08-13
  Clinical Trial Update: A Study of Revumenib in Combination With Chemotherapy in Participants With R/R Acute Leukemia [Phase 1]

  Phase 1 study evaluating revumenib in combination with chemotherapy for relapsed/refractory acute leukemias has completed.

• CLINICAL_TRIALS trial_result · 2024-03-19
  Clinical Trial Update: Clofarabine, Idarubicin, Cytarabine, Vincristine Sulfate, and Dexamethasone in Treating Patients With Newly Diagnosed or Relapsed Mixed Phenotype Acute Leukemia [Phase 2]

  Phase 2 trial evaluating a multi-drug regimen (clofarabine, idarubicin, cytarabine, vincristine, and dexamethasone) in newly diagnosed or re…

• CLINICAL_TRIALS trial_result · 2020-04-27
  Clinical Trial Update: Bioelectrical Impedance Measurement for Predicting Treatment Outcome in Patients With Newly Diagnosed Acute Leukemia [NA]

  A completed clinical trial evaluating bioelectrical impedance measurements to predict treatment outcomes in newly diagnosed acute leukemia p…

• CLINICAL_TRIALS trial_result · 2018-12-10
  Clinical Trial Update: Combination Chemotherapy With or Without Lestaurtinib in Treating Younger Patients With Newly Diagnosed Acute Lymphoblastic Leukemia [Phase 3]

  A Phase 3 trial evaluated whether adding lestaurtinib to standard chemotherapy improves outcomes in children with newly diagnosed acute lymp…

• CLINICAL_TRIALS trial_result · 2018-07-19
  Clinical Trial Update: Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer

  This Clinical Trial Update describes a study collecting and storing malignant and related samples from young cancer patients; the trial stat…

• CLINICAL_TRIALS trial_result · 2015-12-10
  Clinical Trial Update: Structural Imaging and Cognitive Functions in Adult Stem Cell Transplant Recipients Treated With Chemotherapy Alone or in Combination With Radiotherapy

  A completed clinical trial update assessing structural brain imaging and cognitive function in adult stem cell transplant recipients treated…

• CLINICAL_TRIALS trial_result · 2013-11-27
  Clinical Trial Update: Deferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic Malignancies [Phase 2]

  Phase 2 trial updating the use of deferasirox for iron overload due to transfusions in patients with hematologic malignancies; study status …

• CLINICAL_TRIALS trial_result · 2013-06-05
  Clinical Trial Update: 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia [Phase 1]

  Phase 1 clinical trial evaluating safety and dosing of 17-N-allylamino-17-demethoxygeldanamycin (tanespimycin) in pediatric patients with re…

• CLINICAL_TRIALS trial_result · 2013-02-07
  Clinical Trial Update: Imatinib Mesylate in Treating Patients With Advanced Cancer and Liver Dysfunction [Phase 1]

  This clinical trial update summarizes a Phase 1 study of Imatinib Mesylate in patients with advanced cancer and liver dysfunction, which has…

• CLINICAL_TRIALS trial_result · 2013-01-11
  Clinical Trial Update: SB-715992 in Treating Patients With Acute Leukemia, Chronic Myelogenous Leukemia, or Advanced Myelodysplastic Syndromes [Phase 1]

  This Phase 1 trial evaluated SB-715992 in adults with various acute leukemias, chronic myeloid leukemia in blast phase, and advanced myelody…