Pyelonephritis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-02-16Clinical Trial Update: Evaluation of the Efficacy and Safety of Intravenous Imipenem/Cilastatin/XNW4107 in Comparison With Meropenem in Hospitalized Adults With cUTI Including AP (EudraCT no. 2022-000061-40) [Phase 3]
Phase 3 clinical trial evaluating intravenous imipenem/cilastatin/XNW4107 vs meropenem in hospitalized adults with complicated urinary tract…
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FDA approval · 2023-02-10FDA Approved: ZEMDRI (PLAZOMICIN) — Supplemental Application (Cipla Therapeutics Inc.)
FDA approved a supplemental application for ZemdrI (plazomicin) from Cipla Therapeutics Inc.
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CLINICAL_TRIALS trial_result · 2022-07-25Clinical Trial Update: Study to Assess the Efficacy, Safety and Pharmacokinetics of Orally Administered Tebipenem Pivoxil Hydrobromide (SPR994) Compared to Intravenous Ertapenem in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) [Phase 3]
Phase 3 trial comparing oral tebipenem pivoxil hydrobromide (SPR994) to IV ertapenem in complicated urinary tract infection and acute pyelon…
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CLINICAL_TRIALS trial_result · 2021-12-01Clinical Trial Update: MK-7625A Versus Meropenem in Pediatric Participants With Complicated Urinary Tract Infection (cUTI) (MK-7625A-034) [Phase 2]
Phase 2 trial comparing MK-7625A to meropenem in pediatric patients with complicated urinary tract infection; study completed with posted re…
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CLINICAL_TRIALS trial_result · 2021-09-29Clinical Trial Update: Meropenem-FL058 Phase 2 Study in the Treatment of Complicated Urinary Tract Infections [Phase 2]
Phase 2 trial update for meropenem-FL058 in complicated urinary tract infection and acute pyelonephritis.
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CLINICAL_TRIALS trial_result · 2020-08-10Clinical Trial Update: A Study to Assess Efficacy and Safety Intravenous Benapenem in Patients With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial evaluating intravenous benapenem for efficacy and safety in patients with complicated urinary tract infecti…
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FDA approval · 2020-07-15FDA Approved: ZEMDRI (PLAZOMICIN) — Supplemental Application (Cipla Therapeutics Inc.)
FDA approved a supplemental application for ZemdrI (plazomicin) submitted by Cipla Therapeutics Inc.
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CLINICAL_TRIALS trial_result · 2020-07-07Clinical Trial Update: IV or IV/PO Omadacycline vs. IV/PO Levofloxacin for the Treatment of Acute Pyelonephritis [Phase 2]
Phase 2 trial comparing IV or IV/PO omadacycline to IV/PO levofloxacin for acute pyelonephritis completed with results posted in 2020.
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FDA approval · 2020-04-22FDA Approved: LEVOFLOXACIN — Original Application (Gland Pharma Limited)
FDA approved an original application for levofloxacin from Gland Pharma Limited, authorizing a generic version of the antibiotic.
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CLINICAL_TRIALS trial_result · 2020-04-22Clinical Trial Update: Treating Pyelonephritis an Urosepsis With Pivmecillinam [Phase 4]
Phase 4 trial update evaluating pivmecillinam for pyelonephritis and urinary tract infections has completed.
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CLINICAL_TRIALS trial_result · 2020-04-03Clinical Trial Update: Management of Sub-Clinical Bacteriuria in Pregnancy [Phase 4]
Phase 4 clinical trial on managing sub-clinical bacteriuria in pregnancy has completed with posted results.
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FDA approval · 2019-11-14FDA Approved: FETROJA — Original Application (Shionogi Inc.)
The FDA approves Fetroja (cefiderocol sulfate tosylate) from Shionogi in an Original New Drug Application for the treatment of complicated u…
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CLINICAL_TRIALS trial_result · 2019-08-29Clinical Trial Update: CSE-1034 (Ceftriaxone+ Sulbactam+ EDTA) Compared to Meropenem in Complicated Urinary Tract Infections (cUTIs) Caused by ESBL Producing Gram Negative Bacteria [Phase 3]
Phase 3 trial comparing CSE-1034 (ceftriaxone+ sulbactam+ EDTA) versus meropenem in complicated urinary tract infections due to ESBL-produci…
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CLINICAL_TRIALS trial_result · 2019-06-05Clinical Trial Update: Evaluation of Safety and Efficacy of Intravenous Sulbactam-ETX2514 in the Treatment of Hospitalized Adults With Complicated Urinary Tract Infections [Phase 2]
Phase 2 clinical trial evaluating intravenous sulbactam-ETX2514 for hospitalized adults with complicated urinary tract infection and acute p…
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CLINICAL_TRIALS trial_result · 2019-05-24Clinical Trial Update: Safety, Tolerability, and Efficacy of MK-7655 (Relebactam) + Imipenem/Cilastatin Versus Imipenem/Cilastatin Alone for Treating Complicated Urinary Tract Infection (cUTI) (MK-7655-003) [Phase 2]
Phase 2 trial evaluating MK-7655 (Relebactam) plus imipenem/cilastatin versus imipenem/cilastatin alone for complicated urinary tract infect…
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CLINICAL_TRIALS trial_result · 2018-12-11Clinical Trial Update: Safety and Efficacy of ZTI-01 (IV Fosfomycin) vs Piperacillin/Tazobactam for Treatment cUTI/AP Infections [Phase 2, Phase 3]
Clinical trial update comparing IV fosfomycin (ZTI-01) to piperacillin/tazobactam for complicated urinary tract infections and acute pyelone…
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CLINICAL_TRIALS trial_result · 2018-12-11Clinical Trial Update: Efficacy, Safety, Tolerability of Vabomere Compared to Best Available Therapy in Treating Serious Infections in Adults [Phase 3]
Phase 3 trial comparing Vabomere to best available therapy in adults with serious infections; completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-09-19Clinical Trial Update: Study of Ceftolozane/Tazobactam (MK-7625A) in Japanese Participants With Uncomplicated Pyelonephritis and Complicated Urinary Tract Infection (MK-7625A-014) [Phase 3]
Phase 3 trial update of ceftolozane/tazobactam in Japanese participants with uncomplicated pyelonephritis and complicated urinary tract infe…
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CLINICAL_TRIALS trial_result · 2018-08-23Clinical Trial Update: A Study of Plazomicin Compared With Meropenem for the Treatment of Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis (AP) [Phase 3]
Phase 3 trial comparing plazomicin to meropenem for complicated urinary tract infection with acute pyelonephritis has completed with results…
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CLINICAL_TRIALS trial_result · 2018-08-22Clinical Trial Update: A Study of Plazomicin Compared With Levofloxacin for the Treatment of Complicated Urinary Tract Infection (cUTI) and Acute Pyelonephritis (AP) [Phase 2]
Phase 2 trial comparing plazomicin to levofloxacin for complicated urinary tract infection and acute pyelonephritis has completed with resul…
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FDA approval · 2018-06-25FDA Approved: ZEMDRI (PLAZOMICIN) — Original Application (Cipla Therapeutics Inc.)
FDA approved ZemdrI (plazomicin) under an original NDA from Cipla Therapeutics Inc. as a new antibiotic for complicated urinary tract infect…
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CLINICAL_TRIALS trial_result · 2018-05-02Clinical Trial Update: Study of Cases of Serious Infections Due to Carbapenem-Resistant Enterobacteriaceae
Completed clinical trial investigating cases of serious infections due to carbapenem-resistant Enterobacteriaceae across multiple infection …
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CLINICAL_TRIALS trial_result · 2017-10-26Clinical Trial Update: Efficacy/Safety of Meropenem-Vaborbactam Compared to Piperacillin-Tazobactam in Adults With cUTI and AP [Phase 3]
Phase 3 trial comparing Meropenem-Vaborbactam to Piperacillin-Tazobactam in adults with complicated urinary tract infection and acute pyelon…
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FDA approval · 2017-08-29FDA Approved: VABOMERE — Original Application (Melinta Therapeutics, LLC)
FDA approved VABOMERE (meropenem-vaborbactam) from Melinta Therapeutics as an original application.
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CLINICAL_TRIALS trial_result · 2017-06-20Clinical Trial Update: Finafloxacin for the Treatment of cUTI and/or Acute Pyelonephritis [Phase 2]
This update reports the completion and posting of results for a Phase 2 trial evaluating finafloxacin for complicated urinary tract infectio…