Pyelonephritis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-03Clinical Trial Results: Patient-Directed Antimicrobial Duration in Acute Uncomplicated Pyelonephritis [Phase 4]
Phase 4 trial results evaluating patient-directed antimicrobial duration for acute uncomplicated pyelonephritis.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: P3 Study to Assess Efficacy and Safety of Cefepime/Nacubactam and Aztreonam/Nacubactam Versus Best Available Therapy for Adults With Infection Due to Carbapenem Resistant Enterobacterales [Phase 3]
A Phase 3 clinical trial update reporting completion of studies evaluating Cefepime/Nacubactam and Aztreonam/Nacubactam vs best available th…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Quasi-Randomized Evaluation of the UCLA Next Day Clinic (NDC) [NA]
This document provides an update on a quasi-randomized UCLA Next Day Clinic clinical trial; the study is currently active but not recruiting…
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: A Study of Oral Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) Compared to Intravenous Imipenem-cilastatin in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) [Phase 3]
Phase 3 trial comparing oral tebipenem pivoxil hydrobromide to intravenous imipenem-cilastatin in adults with complicated urinary tract infe…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: Factors and Prognosis of Obstructive Pyelonephritis Patients
A completed clinical trial evaluating factors associated with prognosis in obstructive pyelonephritis. Sponsored by Assistance Publique - Hô…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: 3-day IV Antibiotic Treatment Versus 3-day IV Followed by 7-day Oral Antibiotic Treatment for AP in Children [Phase 4]
Phase 4 pediatric trial comparing 3-day IV antibiotics alone versus 3-day IV followed by 7-day oral antibiotics for acute pyelonephritis; cu…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Meropenem-Vaborbactam in Children With Complicated Urinary Tract Infection, Including Acute Pyelonephritis [Phase 2]
Phase 2 study assessing safety, tolerability, and pharmacokinetics of meropenem-vaborbactam in children with complicated urinary tract infec…
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CLINICAL_TRIALS trial_result · 2025-11-25Clinical Trial Update: Efficacy and Safety of Cefepime/Nacubactam or Aztreonam/Nacubactam Compared to Imipenem/Cilastatin in Subjects With Complicated Urinary Tract Infections or Acute Uncomplicated Pyelonephritis [Phase 3]
Phase 3 results comparing cefepime/nacubactam or aztreonam/nacubactam against imipenem/cilastatin for complicated urinary tract infection an…
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FDA approval · 2025-10-22FDA Approved: CONTEPO — Original Application (Meitheal Pharmaceuticals Inc.)
The FDA approved Contepo (fosfomycin disodium) from Meitheal Pharmaceuticals as a new intravenous antibiotic under NDA212271 for the treatme…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Study of Cefepime-zidebactam (FEP-ZID) in Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) [Phase 3]
A Phase 3 clinical trial evaluating cefepime-zidebactam (FEP-ZID) for complicated urinary tract infection and acute pyelonephritis has compl…
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Patient-Directed Antimicrobial Duration in Acute Uncomplicated Pyelonephritis [Phase 4]
Phase 4 clinical trial update on patient-directed antimicrobial duration for acute uncomplicated pyelonephritis; the study status is complet…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Population Pharmacokinetics of Temocillin in Acute Enterobacterial Pyelonephritis in Children
This clinical trial update notes a population pharmacokinetics study of temocillin in children with acute enterobacterial pyelonephritis, wi…
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CLINICAL_TRIALS trial_result · 2025-02-27Clinical Trial Update: Duration of Antibiotic Therapy in Acute Kidney Graft Pyelonephritis (AGPN): Effect on the Risk of Recurrence
This clinical trial update discusses how the duration of antibiotic therapy for acute pyelonephritis in kidney transplant recipients may aff…
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CLINICAL_TRIALS trial_result · 2025-01-31Clinical Trial Update: Plasma NGAL in APN Patients
A trial evaluating plasma NGAL in patients with acute pyelonephritis has completed.
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: A Trial of HRS-8427 in the Treatment of Adults With Complicated Urinary Tract Infection, Including Acute Pyelonephritis [Phase 3]
HRS-8427 is being evaluated in a Phase 3 trial for adults with complicated urinary tract infection, including acute pyelonephritis, and is c…
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: Efficacy and Safety of CAZ-AVI in the Treatment of Infections Due to Carbapenem-resistant G- Pathogens in Chinese Adults [Phase 4]
Phase 4 trial results evaluate the efficacy and safety of ceftazidime-avibactam (CAZ-AVI) for carbapenem-resistant Gram-negative infections …
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CLINICAL_TRIALS research · 2024-08-14Clinical Trial Update: Expanded Access Use of Sulopenem Etzadroxil/Probenecid for Complicated Urinary Tract Infection
Expanded access for sulopenem etzadroxil/probenecid in complicated urinary tract infection and acute pyelonephritis is no longer available.
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Safety and Efficacy Study of Cefepime/VNRX-5133 in Patients With Complicated Urinary Tract Infections [Phase 3]
Phase 3 trial evaluating the safety and efficacy of Cefepime/VNRX-5133 for complicated urinary tract infections, including acute pyelonephri…
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CLINICAL_TRIALS research · 2024-05-29Clinical Trial Update: Efficacy of 7 Days Versus 14 Days of Antibiotic Therapy for Acute Pyelonephritis in Kidney Transplant Recipients, a Multicentre Randomized Non-inferiority Trial. [Phase 3]
A Phase 3 multicentre randomized trial compares 7 days versus 14 days of antibiotic therapy for acute pyelonephritis in kidney transplant re…
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EMA approval · 2024-03-22EMA Authorised: Exblifep (cefepime dihydrochloride monohydrate;Enmetazobactam) — Advanz Pharma Limited
Exblifep has been authorised for multiple infections including urinary tract infections, pyelonephritis, healthcare-associated pneumonia, an…
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CLINICAL_TRIALS trial_result · 2023-11-22Clinical Trial Update: A Trial of Intravenous HRS-8427 in the Treatment of Adults With Complicate Urinary Tract Infection, Including Acute Pyelonephritis [Phase 2]
Phase 2 clinical trial update for intravenous HRS-8427 in adults with complicated urinary tract infection, including acute pyelonephritis.
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CLINICAL_TRIALS trial_result · 2023-11-18Clinical Trial Update: Impact on the Intestinal Microbiota of Treatment With Ceftriaxone in Women's Acute Community Pyelonephritis [Phase 4]
Phase 4 trial update examining how ceftriaxone treatment affects the intestinal microbiota in acute pyelonephritis in women.
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CLINICAL_TRIALS trial_result · 2023-11-13Clinical Trial Update: NRX-101 for Complicated Urinary Tract Infection (UTI) Including Pyelonephritis [Phase 2]
A Phase 2 clinical trial update for NRX-101 in complicated urinary tract infections including pyelonephritis is listed with unknown status.
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CLINICAL_TRIALS trial_result · 2023-09-05Clinical Trial Update: Pharmacokinetics of Ciprofloxacin in Pediatric Patients [Phase 4]
Phase 4 clinical trial update on the pharmacokinetics of ciprofloxacin in pediatric patients with urinary tract infection and pyelonephritis…
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CLINICAL_TRIALS trial_result · 2023-07-17Clinical Trial Update: Study of Cefepime-tazobactam (FEP-TAZ) in Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) [Phase 3]
Phase 3 trial update for cefepime-tazobactam in complicated urinary tract infection and acute pyelonephritis; current status is unknown.