Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-02-26Clinical Trial Update: Safety and Efficacy of POL6326 for Mobilization/Transplant of Sibling Donor in Patients With Hematologic Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating safety and efficacy of POL6326 for mobilization and transplant in hematologic malignancies has completed…
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CLINICAL_TRIALS trial_result · 2016-02-26Clinical Trial Update: Basiliximab #2: In-Vivo Activated T-Cell Depletion to Prevent Graft-Versus_Host Disease (GVHD) After Nonmyeloablative Allotransplantation for the Treatment of Blood Cancer [Phase 2]
Phase 2 trial update of Basiliximab to prevent graft-versus-host disease after nonmyeloablative allogeneic transplantation in blood cancers;…
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CLINICAL_TRIALS trial_result · 2016-02-25Clinical Trial Update: Decitabine Combining Modified CAG Followed by HLA Haploidentical Peripheral Blood Mononuclear Cells Infusion for Elderly Patients With Acute Myeloid Leukemia(AML） [Phase 1, Phase 2]
Phase 1/2 trial evaluating decitabine with a modified CAG regimen followed by haploidentical peripheral blood mononuclear cell infusion in e…
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CLINICAL_TRIALS trial_result · 2016-02-25Clinical Trial Update: The Effect of Deferasirox on Response Rate of Acute Leukemia Patients Not Treated by Standard Chemotherapy Regimens [Phase 1]
Phase 1 study examining whether deferasirox alters response rate in patients with acute myeloid leukemia or acute lymphoblastic leukemia who…
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CLINICAL_TRIALS trial_result · 2016-02-23Clinical Trial Update: A Phase I Study of IGN523 in Subjects With Relapsed or Refractory AML [Phase 1]
A Phase I study of IGN523 in relapsed or refractory acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2016-02-23Clinical Trial Update: Phase 1 Study of Terameprocol (EM-1421) in Patients With Leukemia [Phase 1]
Phase 1 study of Terameprocol (EM-1421) in leukemia was terminated; no efficacy results were reported in this update.
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CLINICAL_TRIALS trial_result · 2016-02-22Clinical Trial Update: A Clinical Trial of Cytotoxic T Cells Augmenting Autologous Hematopoietic Stem Cell (AHSC) Transplantation for Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
Phase 1/2 trial evaluating cytotoxic T cells to augment autologous stem cell transplantation for acute myeloid leukemia; the study status is…
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CLINICAL_TRIALS research · 2016-02-17Clinical Trial Update: A 5 Day Course of Fludarabine and Cytarabine Followed by Full Intensity Allogeneic Stem Cell Transplantation (FA5-Bucy) in Treating Patients With High-risk, Recurrent or Refractory Acute Leukemia and Advanced Myelodysplastic Syndrome
A clinical trial update describes a five-day course of fludarabine and cytarabine followed by full-intensity allogeneic stem cell transplant…
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CLINICAL_TRIALS trial_result · 2016-02-15Clinical Trial Update: A Single Arm Pilot Study of Azacitidine in Myelodysplastic Syndromes (MDS) / Acute Myeloid Leukaemia (AML), With Eltrombopag Support for Thrombocytopenia [Phase 2]
Phase 2 single-arm pilot trial evaluating azacitidine in myelodysplastic syndromes and acute myeloid leukemia with eltrombopag support for t…
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CLINICAL_TRIALS trial_result · 2016-02-15Clinical Trial Update: Decitabine Maintenance for Acute Myelogenous Leukemia (AML) and Myelodysplastic Syndrome (MDS) Post Transplant [Phase 1]
This Phase 1 trial update reports the completion of maintenance decitabine after transplantation for patients with acute myeloid leukemia or…
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CLINICAL_TRIALS trial_result · 2016-02-11Clinical Trial Update: Sorafenib Tosylate and Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating sorafenib tosylate in combination with chemotherapy for older patients with acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2016-02-10Clinical Trial Update: Study of Dasatinib and All-Trans Retinoic Acid for Relapsed/Refractory and/or Elderly Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome [Phase 1]
This Phase 1 trial studied the combination of dasatinib and all-trans retinoic acid in relapsed/refractory and/or elderly patients with acut…
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CLINICAL_TRIALS trial_result · 2016-02-05Clinical Trial Update: Study Evaluating Sorafenib Added to Standard Primary Therapy in Patients With Newly Diagnosed Acute Myeloid Leukemia Less Than 60 Years of Age [Phase 2]
A Phase 2 trial evaluating adding sorafenib to standard primary therapy in newly diagnosed acute myeloid leukemia patients under 60 has comp…
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CLINICAL_TRIALS trial_result · 2016-02-02Clinical Trial Update: Early Response Assessment of Induction Chemotherapy in Acute Myeloid Leukemia Patients Using F-18 FLT PET/CT [NA]
This entry describes a clinical trial evaluating early response to induction chemotherapy in acute myeloid leukemia using F-18 FLT PET/CT. T…
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CLINICAL_TRIALS trial_result · 2016-01-28Clinical Trial Update: Efficacy and Toxicity of Increasing Doses of Idarubicin, Cytarabine and G-CSF in Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial assessing increasing doses of idarubicin and cytarabine with G-CSF in de novo acute myeloid leukemia, reporting effic…
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CLINICAL_TRIALS research · 2016-01-28Clinical Trial Update: Treatment of Relapsed and/or Chemotherapy Refractory CD33 Positive Acute Myeloid Leukemia by CART-33 [Phase 1, Phase 2]
Clinical trial update for CART-33 CAR-T therapy targeting CD33 in relapsed or chemotherapy-refractory acute myeloid leukemia; the trial incl…
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CLINICAL_TRIALS trial_result · 2016-01-15Clinical Trial Update: Phase I/II Study of Mitoxantrone, Etoposide and Gemtuzumab Ozogamicin for Acute Myeloid Leukemia [Phase 1]
Phase I/II trial evaluating mitoxantrone, etoposide, and gemtuzumab ozogamicin for acute myeloid leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2016-01-05Clinical Trial Update: Autologous Peripheral Blood Stem Cell Transplantation With In Vivo Purging as an Alternate Stem Cell Transplantation Program for Pts w/AML in 1st & 2nd Complete Remission w/no HLA Matched Related Donor [NA]
Autologous peripheral blood stem cell transplantation with in vivo purging is explored as an alternative transplantation option for acute my…
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CLINICAL_TRIALS trial_result · 2015-12-31Clinical Trial Update: Safety and Efficacy Study of Donor Natural Killer Cells Given After Haploidentical Hematopoietic Cell Transplantation [Phase 1, Phase 2]
A Phase 1/2 study assessed safety and efficacy of donor natural killer cells given after haploidentical hematopoietic cell transplantation i…
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CLINICAL_TRIALS trial_result · 2015-12-31Clinical Trial Update: Donor Stem Cell Transplant or Bone Marrow Transplant in Treating Patients With Acute Myeloid Leukemia in Remission [Phase 2]
Status update for a Phase 2 trial evaluating donor stem cell transplant or bone marrow transplant in patients with acute myeloid leukemia in…
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CLINICAL_TRIALS withdrawal · 2015-12-30Clinical Trial Update: ALFA-0703 Study in Older Patients With Acute Myeloblastic Leukemia (AML) [Phase 3]
The ALFA-0703 Phase 3 trial in older patients with acute myeloid leukemia has been withdrawn from the program.
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CLINICAL_TRIALS trial_result · 2015-12-28Clinical Trial Update: Umbilical Cord Blood (UCB) Transplantation in Pediatric Patients With High Risk Leukemia and Myelodysplasia [NA]
Clinical trial results for umbilical cord blood transplantation in pediatric patients with high-risk leukemia and myelodysplasia; the study …
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CLINICAL_TRIALS trial_result · 2015-12-22Clinical Trial Update: A Study of the Safety and Preliminary Efficacy of Oral Midostaurin (PKC412) in Relapsed or Refractory Pediatric Leukemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial update reports safety and preliminary efficacy data for oral midostaurin (PKC412) in relapsed or refractory pedia…
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CLINICAL_TRIALS trial_result · 2015-12-21Clinical Trial Update: Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501) [Phase 3]
Phase 3 clinical trial comparing single versus double umbilical cord blood transplants in children with high-risk leukemia and myelodysplasi…
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CLINICAL_TRIALS trial_result · 2015-12-16Clinical Trial Update: Photochemotherapy and Graft-versus-leukemia in Acute-leukemia
This clinical trial update reports a completed study from Karolinska University Hospital evaluating photochemotherapy to enhance graft-versu…