Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-11-15Clinical Trial Update: Feasibility and Outcomes of Allogeneic HCT Compared to Chemotherapy in Older AML Patients
A completed clinical trial comparing allogeneic hematopoietic cell transplantation to chemotherapy in older AML patients, with results poste…
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CLINICAL_TRIALS trial_result · 2019-11-14Clinical Trial Update: Daunorubicin Hydrochloride, Cytarabine, and Nilotinib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 2]
A Phase 2 trial evaluating daunorubicin hydrochloride, cytarabine, and nilotinib in newly diagnosed adult acute myeloid leukemia has been co…
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CLINICAL_TRIALS trial_result · 2019-10-25Clinical Trial Update: Phase I/II Study of DFP-10917 in Patients With Acute Leukemia [Phase 1, Phase 2]
Phase I/II clinical trial update for DFP-10917 in acute leukemia (AML and ALL) has been completed.
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CLINICAL_TRIALS trial_result · 2019-10-21Clinical Trial Update: Management of Platelet Transfusion Therapy in Patients With Blood Cancer or Treatment-Induced Thrombocytopenia [Phase 2]
Phase 2 clinical trial assessing management of platelet transfusion therapy in patients with blood cancers or treatment-induced thrombocytop…
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CLINICAL_TRIALS trial_result · 2019-10-17Clinical Trial Update: A Study of ASP2215 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase (FLT3) Mutation [Phase 3]
Phase 3 study comparing ASP2215 (gilteritinib) to salvage chemotherapy in adults with relapsed or refractory FLT3-mutated acute myeloid leuk…
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CLINICAL_TRIALS trial_result · 2019-10-15Clinical Trial Update: Interleukin-21 (IL-21)- Expanded Natural Killer Cells for Induction of Acute Myeloid Leukemia [Phase 1, Phase 2]
A clinical trial evaluating interleukin-21 expanded natural killer cells for induction therapy in acute myeloid leukemia (Phase 1/Phase 2).
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CLINICAL_TRIALS trial_result · 2019-10-11Clinical Trial Update: Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer [Phase 2]
Phase 2 clinical trial update on donor umbilical cord blood transplant for hematologic cancers; status completed with results posted.
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FDA approval · 2019-10-09FDA Approved: DECITABINE — Supplemental Application (Dr. Reddy's Laboratories Inc.)
FDA approved a supplemental application for Decitabine from Dr. Reddy's Laboratories Inc., expanding regulatory approval for this generic hy…
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CLINICAL_TRIALS trial_result · 2019-10-08Clinical Trial Update: Azacitidine and Lenalidomide for Relapsed and Refractory Patients With Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating azacitidine and lenalidomide in relapsed/refractory acute myeloid leukemia has completed with results post…
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CLINICAL_TRIALS trial_result · 2019-10-07Clinical Trial Update: Clofarabine With Cytarabine for Patients With Minimal Residual Disease Positive Leukemia [Phase 2]
Phase 2 trial of clofarabine with cytarabine in patients with minimal residual disease-positive acute leukemia was terminated; results poste…
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FDA approval · 2019-09-27FDA Approved: IDHIFA — Supplemental Application (Celgene Corporation)
The FDA approved a supplemental application for IDHIFA (enasidenib mesylate) from Celgene, updating the labeling and/or expanding its indica…
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CLINICAL_TRIALS trial_result · 2019-09-24Clinical Trial Update: Lirilumab and Azacitidine in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating lirilumab with azacitidine in refractory or relapsed acute myeloid leukemia was terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-09-24Clinical Trial Update: Omacetaxine for Consolidation and Maintenance [Phase 2]
Phase 2 clinical trial of omacetaxine for consolidation and maintenance in acute myeloid leukemia has been terminated with results posted.
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CLINICAL_TRIALS trial_result · 2019-09-19Clinical Trial Update: Multi-CAR T Cell Therapy Targeting CD7-positive Malignancies [Phase 1, Phase 2]
A multi-CAR T therapy targeting CD7 is being studied in Phase 1/Phase 2 for CD7-positive malignancies including T-cell acute lymphoblastic l…
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CLINICAL_TRIALS trial_result · 2019-09-19Clinical Trial Update: A Dose Escalation Phase I Study to Assess the Safety and Clinical Activity of Multiple Cancer Indications [Phase 1, Phase 2]
A dose-escalation Phase I study is evaluating safety and preliminary activity of a multi-indication cancer therapy in acute myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2019-09-17Clinical Trial Update: Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia [Phase 3]
Phase 3 trial comparing caspofungin to fluconazole for preventing invasive fungal infections in patients undergoing chemotherapy for acute m…
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CLINICAL_TRIALS trial_result · 2019-09-12Clinical Trial Update: Study of DAC Combined With HAAG Regimen in Newly Diagnosed Younger AML Patients [Phase 3]
Phase 3 trial evaluating DAC combined with the HAAG regimen in newly diagnosed younger patients with acute myeloid leukemia undergoing induc…
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CLINICAL_TRIALS trial_result · 2019-09-12Clinical Trial Update: Trial of Daily Pulse Interleukin-2 With Famotidine in Acute Myelogenous Leukemia [Phase 2]
Phase 2 trial of daily pulse interleukin-2 with famotidine in acute myeloid leukemia was terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-09-11Clinical Trial Update: Allogeneic HCT Using Nonmyeloablative Host Conditioning With TLI & ATG vs SOC in AML [Phase 3]
Phase 3 trial comparing nonmyeloablative host conditioning with TLI & ATG to standard of care in acute myeloid leukemia; study terminated wi…
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CLINICAL_TRIALS trial_result · 2019-09-10Clinical Trial Update: Study of DAC Combined With HAAG Regimen in Newly Diagnosed AML Patients Older Than 60 [Phase 3]
APhase 3 trial evaluating DAC plus HAAG regimen for newly diagnosed AML patients over 60 years old; current status is unknown.
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CLINICAL_TRIALS trial_result · 2019-09-06Clinical Trial Update: WEE1 Inhibitor AZD1775 With or Without Cytarabine in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating the WEE1 inhibitor AZD1775 with or without cytarabine in advanced acute myeloid leukemia or myelodysplastic syndrom…
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CLINICAL_TRIALS research · 2019-09-06Clinical Trial Update: Electrophysiological Biomarkers of Chemotherapy-related Cognitive Impairment and Recovery
Clinical trial assessing electrophysiological biomarkers of chemotherapy-related cognitive impairment and recovery; study completed with pos…
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CLINICAL_TRIALS trial_result · 2019-08-26Clinical Trial Update: Sorafenib for Prophylaxis of Leukemia Relapse in Allo-HSCT Recipients With FLT3-ITD Positive AML [Phase 2, Phase 3]
Clinical trial evaluating sorafenib to prevent leukemia relapse after allogeneic stem cell transplantation in FLT3-ITD positive AML; complet…
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CLINICAL_TRIALS trial_result · 2019-08-20Clinical Trial Update: Cladribine in Combination With CAG in Patients With Refractory/Relapsed Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating a cladribine-based combination (CAG) in patients with refractory/relapsed acute myeloid leukemia; status is current…
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CLINICAL_TRIALS trial_result · 2019-08-07Clinical Trial Update: Midostaurin and Decitabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia and FLT3 Mutation [Phase 2]
Phase 2 clinical trial investigating midostaurin plus decitabine in older adults with newly diagnosed AML and FLT3 mutation; study status te…