Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-03-09Clinical Trial Update: Phase 2, Open-Label, Single Arm Study, With BST-236 in Adults With R/R AML or Higher-Risk MDS [Phase 2]
Phase 2, open-label, single-arm study evaluating BST-236 in adults with relapsed/refractory AML or higher-risk MDS.
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CLINICAL_TRIALS trial_result · 2023-03-03Clinical Trial Update: Pevonedistat, Azacitidine, Fludarabine Phosphate, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 1]
Phase 1 study of pevonedistat plus azacitidine, fludarabine phosphate, and cytarabine in relapsed or refractory acute myeloid leukemia or my…
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CLINICAL_TRIALS trial_result · 2023-03-01Clinical Trial Update: Study of Azacitidine in Combination With Pembrolizumab in R/R AML Patients and in Newly Diagnosed Older Patients [Phase 2]
Phase 2 study evaluating azacitidine with pembrolizumab in relapsed/refractory AML and newly diagnosed older patients; study completed with …
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CLINICAL_TRIALS trial_result · 2023-02-27Clinical Trial Update: Study of Chemotherapy in Combination With All-trans Retinoic Acid (ATRA) With or Without Gemtuzumab Ozogamicin in Patients With Acute Myeloid Leukemia (AML) and Mutant Nucleophosmin-1 (NPM1) Gene Mutation [Phase 3]
Phase 3 trial evaluating chemotherapy with ATRA with or without gemtuzumab ozogamicin in AML patients with NPM1 mutation has completed.
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CLINICAL_TRIALS trial_result · 2023-02-27Clinical Trial Update: Onvansertib in Combination With Either Low-dose Cytarabine or Decitabine in Adult Patients With Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
Phase 1/2 trial updating onvansertib in combination with low-dose cytarabine or decitabine for adult acute myeloid leukemia; study status co…
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CLINICAL_TRIALS trial_result · 2023-02-21Clinical Trial Update: Azacitidine in Combination With Venetoclax Treatment for MRD Positive Post Allo-HSCT AML/MDS Patients [Phase 2]
Phase 2 clinical trial update evaluating azacitidine in combination with venetoclax for MRD-positive post allogeneic stem cell transplant AM…
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CLINICAL_TRIALS trial_result · 2023-02-21Clinical Trial Update: A Pilot Study of Dociparstat Sodium (ODSH) in Acute Myeloid Leukemia [Phase 1]
Phase 1 pilot study update on dociparstat sodium (ODSH) in acute myeloid leukemia has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-02-17Clinical Trial Update: TL-895 and KRT-232 Study in Acute Myeloid Leukemia [Phase 1, Phase 2]
A clinical trial update for TL-895 and KRT-232 in Acute Myeloid Leukemia, covering Phase 1 and Phase 2 studies.
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CLINICAL_TRIALS trial_result · 2023-02-16Clinical Trial Update: Panobinostat Maintenance After HSCT fo High-risk AML and MDS [Phase 3]
Phase 3 trial update on panobinostat maintenance after stem cell transplant in high-risk AML and MDS was terminated.
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CLINICAL_TRIALS trial_result · 2023-02-15Clinical Trial Update: "InDACtion" vs "3+7" Induction in AML [Phase 3]
A Phase 3 trial comparing InDACtion versus 3+7 induction in acute myeloid leukemia is ongoing, with unknown status.
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CLINICAL_TRIALS trial_result · 2023-02-08Clinical Trial Update: Study of ProTmune for Allogeneic HCT in Adult Patients With Hematologic Malignancies [Phase 1, Phase 2]
Phase 1/2 trial of ProTmune for allogeneic hematopoietic cell transplantation in adults with hematologic malignancies completed; results pos…
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CLINICAL_TRIALS trial_result · 2023-02-06Clinical Trial Update: Study to Investigate the Safety and Clinical Activity of GSK3326595 and Other Agents to Treat Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
A terminated Phase 1/2 clinical trial investigating GSK3326595 and other agents for myelodysplastic syndrome and acute myeloid leukemia has …
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CLINICAL_TRIALS trial_result · 2023-02-01Clinical Trial Update: Cytokine-induced Memory-like NK Cells in Patients With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) [Phase 1, Phase 2]
Phase 1/2 trial investigating cytokine-induced memory-like NK cells in patients with acute myeloid leukemia or myelodysplastic syndrome; stu…
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CLINICAL_TRIALS trial_result · 2023-01-31Clinical Trial Update: Tac, Mini-MTX, MMF Versus Tac, MTX for GVHD Prevention [Phase 3]
Phase 3 trial comparing Tacrolimus plus mini-methotrexate versus Tacrolimus plus methotrexate for graft-versus-host disease prevention has c…
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CLINICAL_TRIALS trial_result · 2023-01-27Clinical Trial Update: A Study of Venetoclax in Combination With Azacitidine Versus Azacitidine in Treatment Naïve Participants With Acute Myeloid Leukemia Who Are Ineligible for Standard Induction Therapy [Phase 3]
This Phase 3 trial compares venetoclax plus azacitidine to azacitidine alone in newly diagnosed AML patients ineligible for standard inducti…
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CLINICAL_TRIALS trial_result · 2023-01-27Clinical Trial Update: A Study of Venetoclax in Combination With Azacitidine Versus Azacitidine in Treatment Naïve Participants With Acute Myeloid Leukemia Who Are Ineligible for Standard Induction Therapy [Phase 3]
A Phase 3 trial compares venetoclax plus azacitidine versus azacitidine alone in treatment-naïve AML patients ineligible for standard induct…
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CLINICAL_TRIALS trial_result · 2023-01-25Clinical Trial Update: Low-dose Venetoclax and Azacitidine as Front-line Therapy in Newly Diagnosed AML [Phase 2]
Phase 2 trial assessing low-dose venetoclax and azacitidine as front-line therapy for newly diagnosed acute myeloid leukemia completed.
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CLINICAL_TRIALS trial_result · 2023-01-23Clinical Trial Update: Adoptive Immunotherapy in Relapsed Hematological Malignancy: Early GVHD Prophylaxis [Phase 2]
Phase 2 trial of adoptive immunotherapy in relapsed hematological malignancies with early GVHD prophylaxis has completed enrollment and post…
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CLINICAL_TRIALS trial_result · 2023-01-20Clinical Trial Update: Study of Liposomal Annamycin for the Treatment of Subjects With Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
Phase 1/2 clinical trial investigating liposomal annamycin for acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2022-12-22Clinical Trial Update: A Study of Ribavirin to Treat M4 and M5 Acute Myelocytic Leukemia [Phase 2]
Phase 2 clinical trial evaluating ribavirin for Acute Myelocytic Leukemia has completed.
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CLINICAL_TRIALS trial_result · 2022-12-16Clinical Trial Update: Azacitidine Combined With Venetoclax and ATRA in Newly Diagnosed AML [Phase 3]
Phase 3 trial investigating azacitidine combined with venetoclax and ATRA for newly diagnosed acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2022-12-16Clinical Trial Update: Fludarabine and Busulfan vs. Fludarabine, Busulfan and Total Body Irradiation [Phase 3]
A Phase 3 randomized trial comparing Fludarabine and Busulfan versus Fludarabine, Busulfan plus Total Body Irradiation in patients with myel…
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CLINICAL_TRIALS trial_result · 2022-12-13Clinical Trial Update: Efficacy/Safety of CPI-613 in Combination With HD Cyt. and Mito. vs HD Cyt. and Mito. in Older Patients With R/R AML [Phase 3]
Phase 3 trial evaluating CPI-613 with HD cytarabine and mitoxantrone versus HD cytarabine and mitoxantrone in older patients with relapsed/r…
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FDA approval · 2022-12-01FDA Approved: REZLIDHIA — Original Application (Rigel Pharmaceuticals, Inc.)
The FDA approved Rezlidhia (olutasidenib) through an original application for adults with IDH1-mutant acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2022-11-29Clinical Trial Update: Pyronaridine in Acute Lymphoblastic Leukemia (ALL) and Acute Myeloid Leukemia (AML) [Phase 2]
Phase 2 clinical trial update for pyronaridine in acute myeloid leukemia and acute lymphoblastic leukemia is in progress with unknown status…