Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: CHIP-AML22/Quizartinib: Quizartinib + Chemotherapy in Newly Diagnosed Pediatric FLT3-ITD+ and NPM1wt AML Patients [Phase 2]
Phase 2 clinical trial evaluating quizartinib in combination with chemotherapy for newly diagnosed pediatric FLT3-ITD+ and NPM1wt acute myel…
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: CHIP-AML22/Master: An Open Label Complex Clinical Trial in Newly Diagnosed Pediatric de Novo AML Patients [Phase 3]
Open-label Phase 3 clinical trial CHIP-AML22/Master for newly diagnosed pediatric de novo acute myeloid leukemia is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: Chidamide, Venetoclax, and Azacitidine for Newly Diagnosed Acute Myeloid Leukemia [NA]
A clinical trial evaluating the combination of chidamide, venetoclax, and azacitidine for newly diagnosed acute myeloid leukemia is currentl…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: A Study of PEP07 (Checkpoint Kinase 1 Inhibitor) in Patients With Advanced Cancer [Phase 1]
A Phase 1 study of PEP07, a Checkpoint Kinase 1 (CHK1) inhibitor, is currently recruiting in patients with acute myeloid leukemia and mantle…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Maintenance Therapy With Selinexor and Azacitidine in TP53 Mutant AML/MDS After Transplantation [Phase 1]
This document provides an update on a Phase 1 trial evaluating maintenance therapy with selinexor and azacitidine in patients with TP53-muta…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Impact of Optical Genome Mapping in Acute Myeloblastic Leukemia
This item reports a completed clinical trial evaluating the impact of Optical Genome Mapping in acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2025-07-29Clinical Trial Update: Donor-Derived Anti-CD33 CAR T Cell Therapy (VCAR33) in Patients With Relapsed or Refractory AML After Allogeneic Hematopoietic Cell Transplant [Phase 1, Phase 2]
Phase 1/2 trial of VCAR33, a donor-derived anti-CD33 CAR T-cell therapy, in relapsed or refractory acute myeloid leukemia after allogeneic h…
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CLINICAL_TRIALS trial_result · 2025-07-29Clinical Trial Update: A Long-term Follow-up Study of Patients Who Received VOR33
This update provides long-term follow-up information for patients treated with VOR33, but the study has been terminated.
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CLINICAL_TRIALS trial_result · 2025-07-29Clinical Trial Update: Efficacy and Safety of VAH as a Bridging Regimen to Allo-HCT in Relapsed/Refractory AML [Phase 2]
A Phase 2 clinical trial is evaluating VAH as a bridging regimen to allogeneic hematopoietic cell transplantation in relapsed/refractory acu…
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CLINICAL_TRIALS trial_result · 2025-07-29Clinical Trial Update: Allogeneic Engineered Hematopoietic Stem Cell Transplant (HCT) Lacking the CD33 Protein, and Post-HCT Treatment With Mylotarg, for Patients With CD33+ AML or MDS [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating an allogeneic engineered hematopoietic stem cell transplant lacking CD33, with post-transplant Mylotarg,…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: The Efficacy of Allogeneic Hematopoietic Stem Cell Transplantation in Newly Diagnosed High-relapse-risk CEBPA Mutant Acute Myeloid Leukemia
This clinical trial investigates the use of allogeneic hematopoietic stem cell transplantation in newly diagnosed high-relapse-risk CEBPA-mu…
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CLINICAL_TRIALS trial_result · 2025-07-29Clinical Trial Update: 225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome [Phase 1]
Phase 1 clinical trial evaluating 225Ac-DOTA-Anti-CD38 (daratumumab radiolabeled with Actinium-225) in combination with fludarabine, melphal…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Compassionate Communication and Advance Care Planning to Improve End of Life Care in Treatment of Hematological Disease (ACT) [NA]
Clinical trial update for ACT evaluating compassionate communication and advance care planning to improve end-of-life care in hematologic di…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Venetoclax-containing Therapy Combined With Microtransplant for Newly Diagnosed AML [Phase 2]
Phase 2 clinical trial evaluating a Venetoclax-containing therapy with microtransplant for newly diagnosed acute myeloid leukemia is current…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Ex Vivo T-Cell-Depleted Haploidentical Transplantation Bridging With Chimeric Antigen Receptor T-cell Therapy and Prophylactic Memory T Cell Infusion for Acute Leukemia [NA]
This document provides a clinical trial update describing a novel transplantation approach for acute leukemia that combines ex vivo T-cell–d…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Assesment of the Immune Response to RSV Vaccine in Patients With Myeloma, Lymphoma and Hematological Leukemia
This clinical trial update assesses the immune response to an RSV vaccine in patients with hematologic cancers, including multiple myeloma, …
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia [NA]
This clinical trial compares specialty-delivered palliative care to oncology-delivered palliative care for adults with relapsed, primary ref…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Reduced ATG Plus Mini PTCy for GVHD Prophylaxis in Haplo-SCT [Phase 2]
Phase 2 trial evaluating reduced ATG plus mini post-transplant cyclophosphamide for graft-versus-host disease prophylaxis in haploidentical …
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Haploidentical Donor Natural Killer Cell Infusion With IL-15 in Acute Myelogenous Leukemia (AML) [Phase 1]
Phase 1 trial update evaluating haploidentical donor natural killer cell infusion with IL-15 in patients with acute myeloid leukemia and mye…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: A Multicenter Trial Evaluating Efficacy and Safety of A Reduced Venetoclax Exposure To Seven Days Versus Standard Continuous Venetoclax Exposure Combined With Azacitidine in Treatment Naïve Subjects With Acute Myeloid Leukemia Who Are Ineligible for Intensive Induction [Phase 3]
Phase 3 multicenter trial comparing a seven-day reduced venetoclax exposure with azacitidine to standard continuous venetoclax exposure with…
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CLINICAL_TRIALS other · 2025-07-24Clinical Trial Update: An Open-label, Dose-Escalation and Dose-Expansion Study of GB3226 in Patients With Relapsed/Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
An open-label Phase 1/2 dose-escalation and dose-expansion study of GB3226 in relapsed/refractory acute myeloid leukemia; trial status is no…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Observational Study on APL-like aCute Myeloid Leukemia: disTInct Phenotype and Early VAscular complicaTions
An observational clinical trial update on acute myeloid leukemia with an APL-like phenotype, focusing on distinct features and early vascula…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: The Risk of Acute Myeloid Leukaemia in Patients With Ewing's Sarcoma
This clinical trial update discusses the risk of developing acute myeloid leukemia in patients diagnosed with Ewing Sarcoma. The study statu…
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CLINICAL_TRIALS trial_result · 2025-07-23Clinical Trial Update: First-in-Human Dose Escalation Study of AFM28 in Patients With Relapsed/Refractory Acute Myeloid Leukemia [Phase 1]
First-in-human Phase 1 dose-escalation study of AFM28 in relapsed/refractory acute myeloid leukemia; the trial status is TERMINATED.
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: Haplo Peripheral Blood Sct In GVHD Prevention [Phase 1]
Phase 1 trial update reporting the completion of a haploidentical peripheral blood stem cell transplantation approach for the prevention of …