Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Randomized Study of ABC-14 Regimen Compared With "3+7" Standard Induction Therapy or AB-14 for ND AML [Phase 2]
This clinical trial update describes a Phase 2 randomized study comparing the ABC-14 regimen with the 3+7 induction therapy or AB-14 for new…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Venetoclax + Azacitidine vs. Induction Chemotherapy in AML [Phase 2]
Phase 2 clinical trial comparing venetoclax plus azacitidine versus induction chemotherapy in acute myeloid leukemia, currently recruiting.
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant [Phase 1]
This clinical trial update describes a Phase 1 study evaluating HA-1 TCR T-cell immunotherapy for relapsed or refractory acute leukemia afte…
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer [Phase 1]
A Phase 1 trial evaluating natural killer cell therapy in combination with Interleukin-2 and the TGF-beta receptor I inhibitor vactosertib f…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Phase I/II Clinical Trial of Universal Donor CD33 CAR Natural Killer Cells for AML [Phase 1, Phase 2]
A Phase I/II trial evaluating universal donor CD33 CAR natural killer cells for relapsed/refractory acute myeloid leukemia; the study status…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Highest Dose of Uproleselan in Combination With Fludarabine and Cytarabine for Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Mixed Phenotype Acute Leukemia Relapsed or Refractory That Expresses E-selectin Ligand on the Cell Membrane [Phase 1]
Phase 1 clinical trial evaluating the highest dose of uproleselan in combination with fludarabine and cytarabine for relapsed or refractory …
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy [Phase 2]
Phase 2 trial evaluating hematopoietic stem cell transplantation using risk-adjusted chemotherapy for patients with Fanconi anemia and sever…
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CLINICAL_TRIALS trial_result · 2025-11-10Clinical Trial Update: Haploidentical BMT With Post-Transplant Cyclophosphamide and Bendamustine [Phase 1]
A Phase 1 clinical trial evaluating a haploidentical bone marrow transplant using post-transplant cyclophosphamide and bendamustine has comp…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome [Phase 1]
Phase 1 clinical trial update on Orca-T after chemotherapy and total marrow and lymphoid irradiation for acute myeloid leukemia, acute lymph…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Danvatirsen Monotherapy Followed by Combination With Venetoclax in Relapsed/Refractory MDS & AML [Phase 1]
Phase 1 clinical trial evaluating danvatirsen as monotherapy followed by combination with venetoclax in relapsed/refractory myelodysplastic …
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Testing Oral Decitabine and Cedazuridine (ASTX727) in Combination With Venetoclax for Higher-Risk Acute Myeloid Leukemia Patients [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial is evaluating oral decitabine/cedazuridine (ASTX727) in combination with venetoclax for higher-risk acute m…
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CLINICAL_TRIALS withdrawal · 2025-11-10Clinical Trial Update: A Study of Dual-SIgnaling Protein 107 (DSP107) for Patients With Hematological Malignancies [Phase 1]
A Phase 1 study of Dual-Signaling Protein 107 (DSP107) in hematologic malignancies has been terminated, including studies in Acute Myeloid L…
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CLINICAL_TRIALS trial_result · 2025-11-10Clinical Trial Update: Decitabine/Cedazuridine and Venetoclax in Combination With Ivosidenib or Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
Phase 1/2 clinical trials are evaluating a combination of decitabine/cedazuridine and venetoclax with either ivosidenib or enasidenib for re…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Novel Digital Application for Patients With Acute Leukemia [NA]
A clinical trial update describes a novel digital application for patients with relapsed, primary refractory, or high-risk acute myeloid leu…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Cognitive Behavioral Therapy in Helping Patients With Acute Myeloid Leukemia or Lymphoma With Cancer-Related Fatigue [Phase 2]
This Phase 2 trial evaluates cognitive behavioral therapy to reduce cancer-related fatigue in patients with acute myeloid leukemia and lymph…
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: Testing Nivolumab to Prevent Disease From Coming Back After Treatment in Patients With Acute Myeloid Leukemia, REMAIN Trial [Phase 2]
This update reports the Phase 2 REMAIN trial results assessing nivolumab to prevent relapse in patients with acute myeloid leukemia after in…
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: Guadecitabine and Donor Lymphocyte Infusion in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Relapsing After Allogeneic Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating guadecitabine in combination with donor lymphocyte infusion for acute myeloid leukemia, chronic myelomonoc…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating a four-drug combination (cladribine, idarubicin, cytarabine, and venetoclax) for acute myeloid leukemia, h…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Personalized NK Cell Therapy in CBT [Phase 2]
A Phase 2 trial from MD Anderson is evaluating personalized NK cell therapy across several hematologic cancers. The study is currently recru…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse [Phase 1, Phase 2]
This clinical trial evaluates decitabine in combination with the FLAG-Ida chemotherapy regimen and total-body irradiation, followed by donor…
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CLINICAL_TRIALS trial_result · 2025-11-05Clinical Trial Update: Geriatric Assessment & Genetic Profiling to Personalize Therapy in Older Adults With Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating geriatric assessment and genetic profiling to personalize therapy for older adults with acute myeloid leukemia; the…
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CLINICAL_TRIALS trial_result · 2025-11-04Clinical Trial Update: IDH1 Inhibition Using Ivosidenib as Maintenance Therapy for IDH1-mutant Myeloid Neoplasms Following Allogeneic Stem Cell Transplantation [Phase 1]
Phase 1 trial evaluating maintenance therapy with the IDH1 inhibitor ivosidenib after allogeneic stem cell transplantation in IDH1-mutant my…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: UPDATE AML: UPdated Disease Monitoring And Treatment for Enhanced Outcomes for Pediatric AML [EARLY_Phase 1]
This clinical trial update describes an early-phase 1 study in pediatric acute myeloid leukemia, focusing on updated disease monitoring and …
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) [Phase 1]
This is a Phase 1 trial evaluating SL-401 (tagraxofusp) in combination with azacitidine or azacitidine plus venetoclax for acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2025-11-03Clinical Trial Update: Omacetaxine and Venetoclax for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Harboring Mutant RUNX1 [Phase 1, Phase 2]
This clinical trial update reports a Phase 1/2 study of the combination omacetaxine mepesuccinate and venetoclax in relapsed or refractory a…