Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Flotetuzumab for the Treatment of Relapsed or Refractory Advanced CD123-Positive Hematological Malignancies [Phase 1]
A Phase 1 trial evaluating flotetuzumab for relapsed or refractory CD123-positive hematologic malignancies has completed, providing initial …
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Combination Navitoclax, Venetoclax and Decitabine for Advanced Myeloid Neoplasms [Phase 1]
Phase 1 clinical trial evaluating a triple combination of navitoclax, venetoclax, and decitabine for advanced myeloid neoplasms. The study i…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Digital Health Intervention for Self-Management and Telemonitoring in Chimeric Antigen Receptor (CAR-T) Therapy [Phase 3]
Phase 3 clinical trial evaluating a digital health intervention for self-management and telemonitoring in CAR-T therapy is currently recruit…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Romiplostim N01 for Platelet Recovery After Haploidentical HSCT [Phase 1]
Phase 1 clinical trial evaluating Romiplostim N01 for platelet recovery after haploidentical hematopoietic stem cell transplantation. The st…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Total Marrow and Lymphoid Irradiation as Conditioning Regimen Before Hematopoietic Cell Transplantation in Patients With Myelodysplastic Syndrome or Acute Leukemia [Phase 2]
Phase 2 clinical trial evaluating Total Marrow and Lymphoid Irradiation as a conditioning regimen before hematopoietic cell transplantation …
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Fractionated Gemtuzumab Ozogamicin in Treating Measurable Residual Disease in Patients With Acute Myeloid Leukemia [Phase 2]
Phase 2 study evaluating fractionated gemtuzumab ozogamicin for patients with measurable residual disease in acute myeloid leukemia is curre…
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FDA approval · 2026-01-27FDA Approved: VYXEOS — Supplemental Application (Jazz Pharmaceuticals, Inc.)
FDA approved a supplemental application for VYXEOS (daunorubicin and cytarabine) liposome from Jazz Pharmaceuticals to support its use in ac…
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: Clinical Study of Anti-CLL1-CD33-NKG2D Bicephali CAR-T for Relapsed/Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating an Anti-CLL1-CD33-NKG2D bicephali CAR-T therapy for relapsed/refractory acute myeloid leukemia is list…
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: KPT-9274 in Patients With Relapsed and Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial evaluating KPT-9274 in patients with relapsed or refractory acute myeloid leukemia has completed, with results post…
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: Atovaquone (Mepron®) Combined With Conventional Chemotherapy for de Novo Acute Myeloid Leukemia (AML) [EARLY_Phase 1]
An early-phase study assessed adding atovaquone to conventional chemotherapy for newly diagnosed acute myeloid leukemia; the trial has compl…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: A Study of Rebecsinib for Patients With Relapsed/Refractory Secondary Acute Myeloid Leukemia or High Risk Myelofibrosis [Phase 1]
This is a Phase 1 clinical trial evaluating rebecsinib in patients with relapsed/refractory secondary acute myeloid leukemia or high-risk my…
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: Co-infusion of Treg-enriched Donor Lymphocytes With CD3-depleted Hematopoietic Stem Cell Graft to Prevent Graft-versus Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation Among Children With Hematologic Malignancies [Phase 2, Phase 3]
A Phase 2/3 clinical trial is evaluating co-infusion of regulatory T cell–enriched donor lymphocytes with a CD3-depleted hematopoietic stem …
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Treosulfan-Based Versus Clofarabine-Based Conditioning Before Donor Hematopoietic Stem Cell Transplant for the Treatment of Myelodysplastic Syndromes or Acute Myeloid Leukemia [Phase 2]
This Phase 2 clinical trial compares treosulfan-based versus clofarabine-based conditioning regimens before donor allogeneic stem cell trans…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia [Phase 1]
Phase 1 clinical trial update evaluating the combination of selinexor and venetoclax with chemotherapy in pediatric and young adult patients…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Dose-Escalation Study of Oral Administration of LP-108 as Monotherapy and in Combination With Azacitidine in Patients With Relapsed or Refractory MDS, CMML, or AML [Phase 1]
Phase 1 dose-escalation trial evaluating LP-108 as monotherapy and in combination with azacitidine in adults with relapsed or refractory mye…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies [Phase 1]
Phase 1 clinical trial evaluating a CD70-directed CAR T-cell therapy for pediatric hematologic malignancies is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Induction and Consolidation With Fludarabine, Cytarabine, Idarubicin, and Venetoclax for the Treatment of Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating induction and consolidation with fludarabine, cytarabine, idarubicin, and venetoclax for acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Chimeric Antigen Receptor T Cell Redirected to Target CD4 Positive Relapsed Refractory Acute Myeloid Leukemia (AML ) as a Bridge to Allogeneic Stem Cell Transplant [Phase 1]
Phase 1 clinical trial evaluating a CD4-targeted CAR T cell therapy for relapsed/refractory acute myeloid leukemia as a bridge to allogeneic…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Ziftomenib + Mezigdomide in Adolesc. and Adults w/ R/R AML [Phase 1]
A Phase 1 trial evaluating the combination of ziftomenib and mezigdomide in adolescents and adults with relapsed or refractory acute myeloid…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Trial of DFP-10917 vs Non-Intensive or Intensive Reinduction for AML Patients in 2nd/3rd/4th Salvage [Phase 3]
A Phase 3 trial evaluating DFP-10917 versus non-intensive or intensive reinduction for acute myeloid leukemia in 2nd to 4th salvage was term…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Phase 1 Study of UniCAR02-T-CD123 in Patients With Selected CD123 Positive Hematologic Malignancies [Phase 1]
A Phase 1 study of UniCAR02-T-CD123 in CD123-positive hematologic malignancies has been terminated, with Acute Myeloid Leukemia included amo…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Dendritic Cell/AML Fusion Cell Vaccine Following Allogeneic Transplantation in AML Patients [Phase 1]
Phase 1 clinical trial of a dendritic cell/AML fusion cell vaccine given after allogeneic transplantation in acute myeloid leukemia patients…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases [Phase 2]
Phase 2 clinical trial evaluating a cord blood transplant using cyclophosphamide, fludarabine, and total-body irradiation in high-risk hemat…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Daunorubicin and Cytarabine With or Without Uproleselan in Treating Older Adult Patients With Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating daunorubicin and cytarabine with or without uproleselan in older adults with acute myeloid leukemia un…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Study of ADI-PEG 20, Venetoclax and Azacitidine in Acute Myeloid Leukemia [Phase 1]
This is a Phase 1 trial update for a three-drug combination (ADI-PEG 20, venetoclax, and azacitidine) in adults with acute myeloid leukemia;…