Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2011-01-21Clinical Trial Update: Phase I AZD2171 in Patients With Relapsed or Refractory AML and Elderly Patients With DeNovo or Secondary AML [Phase 1]
Phase I study evaluating AZD2171 in relapsed/refractory acute myeloid leukemia and in elderly patients with de novo or secondary AML has com…
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CLINICAL_TRIALS trial_result · 2011-01-17Clinical Trial Update: A Pharmacokinetic and Efficacy Study of Amonafide L-malate (AS1413) in Combination With Cytarabine in Patients With Acute Myeloid Leukemia (AML) [Phase 2]
Phase 2 pharmacokinetic and efficacy study evaluating Amonafide L-malate (AS1413) in combination with Cytarabine for acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2010-12-08Clinical Trial Update: Safety, Tolerability, PK and Efficacy of AZD1152 in Patients With Relapsed Acute Myeloid Leukemia [Phase 1]
Phase 1 trial assessing AZD1152 (barasertib) in relapsed acute myeloid leukemia, focusing on safety, tolerability, pharmacokinetics, and pre…
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CLINICAL_TRIALS trial_result · 2010-11-24Clinical Trial Update: Modified-FLAI Induction and Consolidation Chemotherapy in Elderly Patient With Acute Myeloid Leukemia (AML) [Phase 2]
This document reports a Phase 2 trial of Modified-FLAI induction and consolidation chemotherapy in elderly patients with Acute Myeloid Leuke…
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CLINICAL_TRIALS trial_result · 2010-11-17Clinical Trial Update: Safety and Efficacy of Pentostatin and Low Dose TBI With Allogenic Peripheral Blood Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating safety and efficacy of pentostatin with low-dose total body irradiation followed by allogeneic peripheral …
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CLINICAL_TRIALS trial_result · 2010-10-22Clinical Trial Update: Safety and Anti-Disease Activity of CHR-2797 (Tosedostat) in Elderly and/or Treatment Refractory Patients With Acute Myeloid Leukemia (AML) and Multiple Myeloma (MM) [Phase 1, Phase 2]
This trial update reports on the safety and anti-disease activity of CHR-2797 (tosedostat) in elderly and/or treatment-refractory patients w…
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CLINICAL_TRIALS trial_result · 2010-10-20Clinical Trial Update: An Open Label, Single Centre Mass Balance C14 Study in Patients With Acute Myeloid Leukaemia (AML) [Phase 1]
This open-label, single-centre Phase 1 mass balance C-14 study in patients with acute myeloid leukemia has completed.
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CLINICAL_TRIALS research · 2010-10-14Clinical Trial Update: Haploidentical Transplantation With Early Adoptive Transfer of CD56+CD3- NK Cells [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 haploidentical stem cell transplantation strategy using early adoptive transfer of CD56+CD3…
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CLINICAL_TRIALS research · 2010-10-13Clinical Trial Update: Phase III Randomized Study of Amonafide (AS1413) and Cytarabine Versus Daunorubicin and Cytarabine in Patients With Secondary Acute Myeloid Leukemia (AML)- the ACCEDE Study [Phase 3]
A Phase III randomized trial comparing Amonafide (AS1413) with Cytarabine to Daunorubicin with Cytarabine in patients with secondary acute m…
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CLINICAL_TRIALS research · 2010-10-06Clinical Trial Update: Study the Novel Functions and Molecular Mechanisms of Vascular Endothelial Growth Factor-C (VEGF-C) in Acute Myeloid Leukemia (AML)
This document describes a clinical trial investigating the novel functions and molecular mechanisms of vascular endothelial growth factor-C …
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CLINICAL_TRIALS trial_result · 2010-09-29Clinical Trial Update: Phase I Using Velcade & Idarubicin in Elderly and Relapsed AML [Phase 1]
Phase I trial evaluating Velcade (bortezomib) in combination with idarubicin for elderly and relapsed acute myeloid leukemia; the study stat…
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CLINICAL_TRIALS trial_result · 2010-09-24Clinical Trial Update: VELCADE in Combination With Idarubicin and Cytosine Arabinoside in Patients With Acute Myelogenous Leukemia [Phase 1]
Phase 1 study evaluating Velcade (bortezomib) in combination with idarubicin and cytarabine in patients with acute myeloid leukemia has comp…
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CLINICAL_TRIALS trial_result · 2010-09-21Clinical Trial Update: Pravastatin, Idarubicin, and Cytarabine in Treating Patients With Acute Myeloid Leukemia [Phase 1]
A Phase 1 study evaluating the safety and preliminary activity of a three-drug combination—pravastatin, idarubicin, and cytarabine—in patien…
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CLINICAL_TRIALS trial_result · 2010-09-20Clinical Trial Update: Cellular Adoptive Immunotherapy in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndromes That Relapsed After Donor Stem Cell Transplant [Phase 1]
Phase 1 clinical trial update on cellular adoptive immunotherapy for patients with acute myeloid leukemia, acute lymphoblastic leukemia, or …
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CLINICAL_TRIALS trial_result · 2010-09-16Clinical Trial Update: Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndrome, Acute Myeloid Leukemia, or Myeloproliferative Disorder [Phase 1, Phase 2]
Phase 1/2 clinical trial update on donor peripheral stem cell transplantation for patients with acute myeloid leukemia, myelodysplastic synd…
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CLINICAL_TRIALS trial_result · 2010-09-06Clinical Trial Update: Daunorubicin & Cytarabine +/- Zosuquidar inTreating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or Refractory Anemia [Phase 3]
A Phase 3 trial evaluating daunorubicin and cytarabine with or without zosuquidar in older patients with newly diagnosed acute myeloid leuke…
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CLINICAL_TRIALS research · 2010-09-03Clinical Trial Update: Use of Decitabine in Myelodysplastic Syndrome (MDS) Following Azacitidine (AZA) Failure [Phase 2]
Phase 2 clinical trial exploring decitabine for myelodysplastic syndrome after azacitidine failure.
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CLINICAL_TRIALS trial_result · 2010-08-24Clinical Trial Update: Radiolabeled Monoclonal Antibody, Cyclophosphamide, and Total Body Irradiation Followed By Donor Stem Cell Transplantation in Treating Patients With Advanced Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating radiolabeled monoclonal antibody with cyclophosphamide and total body irradiation followed by donor stem cell trans…
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CLINICAL_TRIALS trial_result · 2010-08-20Clinical Trial Update: Therapy of Acute Myeloid Leukemia in Patients Over the Age of 60 : DA Versus Mitoxantrone With Intermittent AraC [Phase 4]
A Phase 4 trial comparing daunorubicin and cytarabine (DA) versus mitoxantrone with intermittent cytarabine in patients over 60 with acute m…
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CLINICAL_TRIALS trial_result · 2010-08-17Clinical Trial Update: Phase I/II, Open-label, Multi-center, Two Part Dose-escalation, Safety, Pharmacokinetics (PK) and Efficacy Study of AZD4877 in Patients With Acute Myelogenous Leukemia (AML) [Phase 1]
Phase I/II open-label dose-escalation study of AZD4877 in acute myeloid leukemia was terminated; results were posted in 2010.
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CLINICAL_TRIALS trial_result · 2010-08-12Clinical Trial Update: Gemtuzumab Ozogamicin in Combination With A-HAM in Refractory AML (GO-A-HAM) [Phase 2]
Phase 2 trial evaluating gemtuzumab ozogamicin in combination with A-HAM in refractory acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2010-08-09Clinical Trial Update: High-Dose Busulfan and High-Dose Cyclophosphamide Followed By Donor Bone Marrow Transplant in Treating Patients With Leukemia, Myelodysplastic Syndrome, Multiple Myeloma, or Recurrent Hodgkin or Non-Hodgkin Lymphoma [Phase 2]
A Phase 2 trial evaluating high-dose busulfan and high-dose cyclophosphamide conditioning followed by donor bone marrow transplantation in p…
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CLINICAL_TRIALS trial_result · 2010-07-27Clinical Trial Update: Autologous Bone Marrow Transplantation in Acute Non-Lymphoblastic Leukemia During First or Subsequent Remission [Phase 2]
Phase 2 clinical trial evaluating autologous bone marrow transplantation for patients with acute myeloid leukemia in first or subsequent rem…
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CLINICAL_TRIALS trial_result · 2010-06-30Clinical Trial Update: Safety, Pharmacokinetics and Pharmacodynamics of TKI258 in Subjects With Acute Myeloid Leukemia [Phase 1]
A Phase 1 study evaluating the safety, pharmacokinetics and pharmacodynamics of TKI258 (dovitinib) in subjects with acute myeloid leukemia, …
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CLINICAL_TRIALS trial_result · 2010-06-22Clinical Trial Update: Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 3]
Phase 3 clinical trial evaluating combination chemotherapy in children with newly diagnosed acute myeloid leukemia or myelodysplastic syndro…