Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-01-23Clinical Trial Update: Decitabine in Treating Children With Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia [Phase 1]
A Phase 1 pediatric trial evaluates decitabine for relapsed or refractory acute myeloid leukemia and acute lymphoblastic leukemia, including…
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CLINICAL_TRIALS trial_result · 2013-01-18Clinical Trial Update: Sodium Salicylate in Treating Patients With Advanced Myelodysplastic Syndrome, Acute Myelogenous Leukemia, or Chronic Lymphocytic Leukemia [Phase 1]
A Phase 1 trial evaluating sodium salicylate in patients with advanced myelodysplastic syndromes, acute myeloid leukemia, or chronic lymphoc…
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myelogenous Leukemia or Myelodysplastic Syndrome [Phase 3]
Phase 3 trial evaluating combination chemotherapy with or without bone marrow transplantation in children with acute myeloid leukemia or mye…
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Raltitrexed in Treating Children With Refractory Acute Leukemia [Phase 1]
This document provides an update on a Phase 1 clinical trial of Raltitrexed for refractory acute leukemia in children, including recurrent c…
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CLINICAL_TRIALS trial_result · 2013-01-15Clinical Trial Update: S0432 Tipifarnib in Treating Older Patients With Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial update on tipifarnib (S0432) in older adults with acute myeloid leukemia; the study has completed.
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CLINICAL_TRIALS trial_result · 2013-01-11Clinical Trial Update: SB-715992 in Treating Patients With Acute Leukemia, Chronic Myelogenous Leukemia, or Advanced Myelodysplastic Syndromes [Phase 1]
This Phase 1 trial evaluated SB-715992 in adults with various acute leukemias, chronic myeloid leukemia in blast phase, and advanced myelody…
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CLINICAL_TRIALS research · 2013-01-11Clinical Trial Update: the Effects and Safety of Idarubicin-strengthened Pretreatment Program and Conventional Busulfan Cyclophosphamide Pretreatment Program on High-risk Acute Myeloid Leukemia Patient [Phase 3]
This clinical trial update describes a Phase 3 study comparing an idarubicin-strengthened pretreatment regimen with a conventional busulfan/…
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CLINICAL_TRIALS trial_result · 2013-01-09Clinical Trial Update: A Phase II Study Of The Farnesyltransferase Inhibitor ZANESTRA (R115777, NSC #702818, IND #58,359) In Complete Remission Following Induction And/Or Consolidation Chemotherapy In Adults With Poor-Risk Acute Myelogenous Leukemia (AML) And High-Risk Myelodysplasia (MDS) [Phase 2]
This status update describes results from a Phase II study of the farnesyltransferase inhibitor tipifarnib (Zarnestra) in adults with poor-r…
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CLINICAL_TRIALS trial_result · 2013-01-09Clinical Trial Update: Sorafenib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Chronic Myelogenous Leukemia [Phase 1]
A Phase 1 trial evaluating sorafenib in adults with relapsed or refractory acute myeloid leukemia, acute lymphoblastic leukemia, or chronic …
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CLINICAL_TRIALS trial_result · 2013-01-09Clinical Trial Update: Chemotherapy Plus Sargramostim in Treating Patients With Refractory Myeloid Cancer [Phase 1]
Phase 1 study assessing the safety of adding sargramostim (GM-CSF) to chemotherapy in patients with refractory myeloid cancers; the trial ha…
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CLINICAL_TRIALS trial_result · 2013-01-09Clinical Trial Update: Tipifarnib and Etoposide in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 1]
A Phase 1 trial evaluating the combination of tipifarnib and etoposide in older adults with newly diagnosed acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2013-01-07Clinical Trial Update: Vaccine Therapy Plus Immune Adjuvant in Treating Patients With Chronic Myeloid Leukemia, Acute Myeloid Leukemia, or Myelodysplastic Syndrome [Phase 1, Phase 2]
This update summarizes a Phase 1/2 clinical trial of a vaccine therapy with an immune adjuvant in patients with chronic myeloid leukemia, ac…
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CLINICAL_TRIALS trial_result · 2013-01-04Clinical Trial Update: Vaccine Therapy in Treating Patients With Acute Myeloid Leukemia [Phase 1]
This entry reports the termination of a Phase 1 clinical trial investigating a vaccine therapy for acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2012-12-24Clinical Trial Update: Phase I Study in RAD 001 Patients With Relapse AML [Phase 1]
Phase I study of RAD 001 (ridaforolimus) in patients with relapsed acute myeloid leukemia has been completed.
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FDA approval · 2012-12-19FDA Approved: VIDAZA — Supplemental Application (Celgene Corporation)
The FDA approved a supplemental application for Vidaza (azacitidine) submitted by Celgene Corporation. This action updates the regulatory st…
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CLINICAL_TRIALS withdrawal · 2012-12-18Clinical Trial Update: Phase 3 Trial for AML Patients in CR2 Comparing 8Gy TBI /Fludarabine to Conditioning With TBI 12Gy/Cyclophosphamide [Phase 3]
Phase 3 AML trial comparing 8 Gy total body irradiation with fludarabine versus 12 Gy TBI with cyclophosphamide was terminated.
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CLINICAL_TRIALS trial_result · 2012-12-17Clinical Trial Update: Efficacy of 5-azacytidine Added to Standard Primary Therapy in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (AML) [Phase 2]
Phase 2 trial evaluating adding 5-azacytidine to standard frontline therapy in elderly patients with newly diagnosed AML has completed. The …
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CLINICAL_TRIALS trial_result · 2012-12-07Clinical Trial Update: Study of Parathyroid Hormone Following Sequential Cord Blood Transplantation From an Unrelated Donor [Phase 2]
Phase 2 study evaluating parathyroid hormone after sequential cord blood transplantation from an unrelated donor; the trial was terminated a…
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FDA approval · 2012-12-05FDA Approved: MITOXANTRONE — Supplemental Application (Meitheal Pharmaceuticals Inc.)
The FDA approved a supplemental application for mitoxantrone from Meitheal Pharmaceuticals Inc., updating the approved generic product under…
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CLINICAL_TRIALS research · 2012-12-04Clinical Trial Update: Safety Study of Anti LewisY Chimeric Antigen Receptor in Myeloma, Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 1]
A Phase 1 safety study evaluating an anti-LewisY chimeric antigen receptor therapy in patients with multiple myeloma, acute myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2012-11-30Clinical Trial Update: Combination Chemotherapy Plus PSC 833 Followed by Interleukin-2 in Treating Patients With Acute Myelogenous Leukemia [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluated combination chemotherapy with PSC-833 (valspodar) followed by interleukin-2 in patients with acute myel…
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CLINICAL_TRIALS trial_result · 2012-11-09Clinical Trial Update: Non-Myeloablative Allogeneic Stem Cell Transplantation With Matched Unrelated Donors for Treatment of Hematologic Malignancies, Renal Cell Carcinoma, and Aplastic Anemia
This clinical trial evaluated non-myeloablative allogeneic stem cell transplantation with matched unrelated donors across several hematologi…
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CLINICAL_TRIALS trial_result · 2012-11-09Clinical Trial Update: Natural Killer (NK) Cell Transplantation for AML [NA]
A completed clinical trial evaluating natural killer cell transplantation for acute myeloid leukemia has posted results in 2012.
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CLINICAL_TRIALS trial_result · 2012-11-08Clinical Trial Update: Risk Adapted Treatment for Primary Acute Myeloid Leukemia (AML) [Phase 2]
A Phase 2 trial evaluating risk-adapted treatment for primary acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2012-11-01Clinical Trial Update: Risk-adapted Therapy for Adult Acute Myeloid Leukemia. [Phase 2]
A Phase 2 clinical trial of risk-adapted therapy for adult acute myeloid leukemia has completed.