Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-06-04Clinical Trial Update: Decitabine, Arsenic Trioxide and Ascorbic Acid for Myelodysplastic Syndromes and Acute Myeloid Leukemia [Phase 1]
Phase 1 clinical trial evaluating the safety of a triple combination of decitabine, arsenic trioxide, and ascorbic acid in patients with mye…
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CLINICAL_TRIALS trial_result · 2013-06-04Clinical Trial Update: 17-N-Allylamino-17-Demethoxygeldanamycin and Bortezomib in Treating Patients With Relapsed or Refractory Hematologic Cancer [Phase 1]
Phase 1 clinical trial evaluating the combination of tanespimycin (17-allylamino-17-demethoxygeldanamycin) and bortezomib in relapsed or ref…
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CLINICAL_TRIALS trial_result · 2013-06-04Clinical Trial Update: Flavopiridol in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Chronic Myelogenous Leukemia [Phase 1]
A Phase 1 clinical trial of flavopiridol (alvocidib) in relapsed or refractory acute myeloid leukemia, acute lymphoblastic leukemia, or chro…
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CLINICAL_TRIALS trial_result · 2013-06-04Clinical Trial Update: Monoclonal Antibody Therapy in Treating Patients With Chronic Lymphocytic Leukemia, Lymphocytic Lymphoma, Acute Lymphoblastic Leukemia, or Acute Myeloid Leukemia [Phase 1]
Phase 1 clinical trial of a monoclonal antibody therapy in patients with chronic lymphocytic leukemia, small lymphocytic lymphoma, acute lym…
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CLINICAL_TRIALS trial_result · 2013-05-29Clinical Trial Update: Accuracy Testing of the Chromosomal Aberration and Gene Mutation Markers of the AMLProfiler
This entry reports a terminated clinical trial (NCT01463410) evaluating the accuracy of chromosomal aberration and gene mutation markers for…
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CLINICAL_TRIALS trial_result · 2013-05-16Clinical Trial Update: Vorinostat in Treating Patients With Acute Myeloid Leukemia [Phase 2]
A Phase 2 trial evaluated the safety and efficacy of vorinostat in adults with acute myeloid leukemia, with results posted after completion.
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FDA approval · 2013-05-06FDA Approved: VIDAZA — Supplemental Application (Celgene Corporation)
The FDA approved a Celgene-supplied supplemental application for Vidaza (azacitidine), updating the drug's labeling and/or indications.
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CLINICAL_TRIALS trial_result · 2013-05-03Clinical Trial Update: Vorinostat, Cytarabine, and Etoposide in Treating Patients With Relapsed and/or Refractory Acute Leukemia or Myelodysplastic Syndromes or Myeloproliferative Disorders [Phase 1]
Phase 1 study evaluating a combination of vorinostat, cytarabine, and etoposide in patients with relapsed or refractory acute leukemia, myel…
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CLINICAL_TRIALS trial_result · 2013-05-03Clinical Trial Update: Combination Chemotherapy and Tipifarnib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial update evaluating the combination of chemotherapy with tipifarnib in patients with newly diagnosed acute myeloid le…
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CLINICAL_TRIALS trial_result · 2013-04-24Clinical Trial Update: Azacytidine for the Treatment of Myelodysplastic Syndromes/Acute Myeloid Leukemia (MDS/AML) With High Risk (Chromosome 7 and or Complex) Cytogenetic Abnormalities [Phase 2]
Phase 2 clinical study evaluating azacitidine for high-risk myelodysplastic syndromes and acute myeloid leukemia with chromosome 7 or comple…
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CLINICAL_TRIALS trial_result · 2013-04-10Clinical Trial Update: Azacitidine in Treating Patients With Newly Diagnosed Previously Untreated or Secondary Acute Myeloid Leukemia Who Are Unsuitable For Intensive Chemotherapy [Phase 2]
Phase 2 study of azacitidine in patients with newly diagnosed or secondary acute myeloid leukemia who are unsuitable for intensive chemother…
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CLINICAL_TRIALS trial_result · 2013-04-09Clinical Trial Update: Deferoxamine for Iron Overload Before Allogeneic Stem Cell Transplantation [NA]
This clinical trial evaluated deferoxamine to manage iron overload before allogeneic stem cell transplantation in patients with acute myeloi…
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CLINICAL_TRIALS trial_result · 2013-04-04Clinical Trial Update: Evaluation of the Anti-CD-33 Immunotoxin Hum-195/rGel in Patients With Advanced Myeloid Malignancies [Phase 1]
Phase 1 study evaluating Hum-195/rGel, an anti-CD-33 immunotoxin, in patients with advanced myeloid malignancies including acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2013-04-02Clinical Trial Update: Flavopiridol and Vorinostat in Treating Patients With Relapsed or Refractory Acute Leukemia or Chronic Myelogenous Leukemia or Refractory Anemia [Phase 1]
Phase 1 trial evaluating flavopiridol and vorinostat in relapsed or refractory acute leukemias and related myeloid disorders has completed e…
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CLINICAL_TRIALS withdrawal · 2013-04-02Clinical Trial Update: A Multi-Center Phase 2 Study of VEGF Trap as a Single Agent in Acute Myeloid Leukemia [Phase 2]
A multi-center Phase 2 study of VEGF Trap as a single agent in acute myeloid leukemia has been withdrawn.
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CLINICAL_TRIALS trial_result · 2013-03-26Clinical Trial Update: Combination of Decitabine and Midostaurin in Patients Older Than 60 With Newly Diagnosed or Relapsed Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 trial evaluating the combination of decitabine and midostaurin in patients over 60 with newly diagnosed or relapsed/refractory acute…
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CLINICAL_TRIALS trial_result · 2013-03-25Clinical Trial Update: Tipifarnib in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating tipifarnib for older patients with previously untreated acute myeloid leukemia has completed, with results reported…
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CLINICAL_TRIALS trial_result · 2013-03-22Clinical Trial Update: S0125, Chemotherapy, Total-Body Irradiation, and Peripheral Stem Cell Transplantation in Treating Older Patients With Acute Myeloid Leukemia [Phase 2]
Phase 2 study (S0125) evaluating chemotherapy with total-body irradiation and peripheral stem cell transplantation in older adults with acut…
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CLINICAL_TRIALS trial_result · 2013-03-14Clinical Trial Update: Methotrexate or Pentostatin for Graft-versus-host Disease Prophylaxis in Risk-adapted Allogeneic Bone Marrow Transplantation for Hematologic Malignancies [Phase 3]
Phase 3 study evaluating methotrexate or pentostatin for graft-versus-host disease prophylaxis in risk-adapted allogeneic bone marrow transp…
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CLINICAL_TRIALS trial_result · 2013-03-12Clinical Trial Update: Decitabine for Myelodysplastic Syndromes and Acute Myeloid Leukemia Before Allogeneic Hematopoietic Cell Transplantation [Phase 4]
A Phase 4 clinical trial is evaluating decitabine given before allogeneic hematopoietic cell transplantation in patients with higher-risk my…
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CLINICAL_TRIALS trial_result · 2013-03-12Clinical Trial Update: Decitabine Augments for Post Allogeneic Stem Cell Transplantation in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome [Phase 2, Phase 3]
This clinical trial update describes the Phase 2/Phase 3 evaluation of decitabine as an adjunct after allogeneic stem cell transplantation i…
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CLINICAL_TRIALS trial_result · 2013-03-08Clinical Trial Update: Reduction of Cord Blood Transplantation Toxicity in Patients With Acute Myeloid Leukemia [Phase 2]
Phase 2 results indicate reduced toxicity from cord blood transplantation in patients with acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2013-03-08Clinical Trial Update: Decitabine and Gemtuzumab Ozogamicin in Acute Myelogenous Leukemia and High-risk Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating decitabine in combination with gemtuzumab ozogamicin in adults with acute myeloid leukemia or high-risk myelodyspla…
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CLINICAL_TRIALS trial_result · 2013-03-04Clinical Trial Update: Randomized Study of Decitabine in Maintenance Therapy of Acute Myeloid Leukemia (AML) [Phase 2, Phase 3]
This document reports results from a randomized Phase 2/3 trial of decitabine as maintenance therapy for acute myeloid leukemia, with result…
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CLINICAL_TRIALS trial_result · 2013-02-28Clinical Trial Update: Velcaflagida in Relapsed or Refractary Acute Myeloid Leukemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Velcaflagida for relapsed or refractory acute myeloid leukemia has completed.