Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2017-12-02Clinical Trial Update: Clofarabine, Cyclophosphamide and Etoposide for Minimal Residual Disease Positive Acute Leukemia [Phase 2]
Phase 2 trial evaluating clofarabine, cyclophosphamide, and etoposide for minimal residual disease-positive acute leukemia has been withdraw…
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CLINICAL_TRIALS withdrawal · 2017-10-19Clinical Trial Update: Donor Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia in Remission [Phase 2]
A Phase 2 trial evaluating donor stem cell transplant for adults with acute myeloid leukemia in remission has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-08-31Clinical Trial Update: iCare3: Monitoring Circulating Cancer DNA After Chemotherapy in MDS and AML
A clinical trial (NCT03138395) investigating monitoring circulating cancer DNA after chemotherapy in Acute myeloid leukemia and Myelodysplas…
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EMA withdrawal · 2017-08-15EMA Application withdrawn: Qinprezo (vosaroxin) — Sunesis Europe Ltd
European EMA withdrawn the application for Qinprezo (vosaroxin) for acute myeloid leukemia.
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CLINICAL_TRIALS withdrawal · 2017-06-02Clinical Trial Update: Dose-Escalation Study of Ponatinib, a FLT3 Inhibitor, With and Without Combination of 5-Azacytidine, in Patients With FLT3-Mutated Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
Phase 1/Phase 2 dose-escalation trial of ponatinib, a FLT3 inhibitor, with and without 5-azacytidine in FLT3-mutated acute myeloid leukemia …
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CLINICAL_TRIALS withdrawal · 2017-05-09Clinical Trial Update: Decitabine and Vaccine Therapy for Patients With Relapsed AML Following Allogeneic Stem Cell Transplantation [Phase 1]
A Phase 1 study of Decitabine combined with a vaccine therapy for relapsed acute myeloid leukemia after allogeneic stem cell transplantation…
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CLINICAL_TRIALS withdrawal · 2017-05-03Clinical Trial Update: Wee1 Kinase Inhibitor AZD1775 and Combination Chemotherapy in Treating Children, Adolescents and Young Adults With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 trial of the Wee1 inhibitor AZD1775 (adavosertib) with combination chemotherapy for relapsed or refractory acute myeloid leukemia …
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CLINICAL_TRIALS withdrawal · 2017-04-20Clinical Trial Update: Open Label Study of Sargramostim Among Patients Receiving Myelosuppressive Induction Chemotherapy for Acute Myelogenous Leukemia [Phase 2]
Open-label Phase 2 trial of sargramostim in patients receiving myelosuppressive induction chemotherapy for acute myeloid leukemia has been w…
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CLINICAL_TRIALS withdrawal · 2017-04-05Clinical Trial Update: A Study of Volasertib Plus Induction Chemotherapy for Acute Myeloid Leukemia [Phase 1]
Phase 1 study of volasertib plus induction chemotherapy for acute myeloid leukemia has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-02-17Clinical Trial Update: Sulindac for Patients With AML [Phase 2]
The Phase 2 clinical trial of sulindac for acute myeloid leukemia has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-01-27Clinical Trial Update: Dose Escalation Study in Acute Myeloid or B-Cell Acute Lymphoblastic Leukemia [Phase 1]
A Phase 1 dose-escalation study in relapsed or refractory acute myeloid leukemia and relapsed/refractory B-cell acute lymphoblastic leukemia…
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CLINICAL_TRIALS withdrawal · 2017-01-27Clinical Trial Update: A Study to Find a Safe Dose of Volasertib Given in Addition to Standard Salvage Chemotherapy in Children (Age 3 Months to Less Than 18 Years) With Acute Myeloid Leukaemia, in Whom Front-line Chemotherapy Failed [Phase 1]
A Phase 1 trial to determine a safe dose of volasertib added to salvage chemotherapy in children with acute myeloid leukemia after frontline…
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CLINICAL_TRIALS withdrawal · 2017-01-10Clinical Trial Update: Telomere and Telomerase
A clinical trial investigating telomere and telomerase in acute myeloid leukemia was withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-12-29Clinical Trial Update: Safety and Effectiveness Study of CPI-613 to Treat Refractory or Relapsed Leukemia and Myelodysplastic Syndrome [Phase 2]
A Phase 2 trial evaluating CPI-613 for refractory or relapsed Acute Myeloid Leukemia and Myelodysplastic Syndrome has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-09-14Clinical Trial Update: Ruxolitinib Phosphate, Tacrolimus and Sirolimus in Preventing Acute Graft-versus-Host Disease During Reduced Intensity Donor Hematopoietic Cell Transplant in Patients With Myelofibrosis [Phase 1]
This Phase 1 trial of a combination of ruxolitinib phosphate, tacrolimus, and sirolimus to prevent acute graft-versus-host disease in patien…
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CLINICAL_TRIALS withdrawal · 2016-09-01Clinical Trial Update: A Study Assessing tOTX015 in Combination With Azacitidine (AZA) or AZA Single Agent in Patients With Newly-diagnosed Acute Myeloid Leukemia (AML) Not Candidate for Standard Intensive Induction Therapy (SIIT) [Phase 1, Phase 2]
A Phase 1/2 study evaluating tOTX015 in combination with azacitidine or azacitidine alone in newly diagnosed acute myeloid leukemia patients…
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CLINICAL_TRIALS withdrawal · 2016-07-14Clinical Trial Update: Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Hematologic Malignancies [Phase 2]
A Phase 2 clinical trial evaluating single or double donor umbilical cord blood transplant for high-risk hematologic malignancies has been w…
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CLINICAL_TRIALS withdrawal · 2015-12-30Clinical Trial Update: ALFA-0703 Study in Older Patients With Acute Myeloblastic Leukemia (AML) [Phase 3]
The ALFA-0703 Phase 3 trial in older patients with acute myeloid leukemia has been withdrawn from the program.
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CLINICAL_TRIALS withdrawal · 2015-08-31Clinical Trial Update: A Phase I Trial of Alloreactive Cell Infusion Following Transplantation of Haplotype Cells in Patients With Myeloid Malignancies [Phase 1]
A Phase I study of an alloreactive cell infusion following transplantation of haplotype cells in patients with myeloid malignancies has been…
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CLINICAL_TRIALS withdrawal · 2015-04-13Clinical Trial Update: A Randomized Study of Epigenetic Priming Using Decitabine With Front Line Induction Chemotherapy Compared With Immediate Induction Chemotherapy in Pediatric Acute Myelogenous Leukemia (AML) Subjects [Phase 2]
Phase 2 randomized pediatric acute myeloid leukemia trial evaluating decitabine epigenetic priming with frontline induction chemotherapy has…
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CLINICAL_TRIALS withdrawal · 2015-04-10Clinical Trial Update: The Role of Maintenance Oral Clofarabine in Older Adults With Acute Myeloid Leukemia [Phase 1]
A Phase 1 trial evaluating maintenance oral clofarabine in older adults with Acute Myeloid Leukemia has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2014-12-11Clinical Trial Update: Early Enteral Tube Feedings in Children Receiving Chemo for AML/MDS & High Risk Solid Tumors [NA]
This clinical trial update indicates that Vanderbilt University’s study on early enteral tube feedings for children undergoing chemotherapy …
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CLINICAL_TRIALS withdrawal · 2014-11-13Clinical Trial Update: Phase 1 Study Evaluating ZEN003365 in Relapsed/Refractory Lymphoproliferative Malignancies or Relapsed/Refractory AML [Phase 1]
Zenith Epigenetics has withdrawn its Phase 1 trial of ZEN003365 for relapsed/refractory lymphoproliferative disorders and acute myeloid leuk…
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CLINICAL_TRIALS withdrawal · 2014-09-18Clinical Trial Update: Aezea® (Cenersen) and Chemotherapy for AML Subjects ≥ 55 Years of Age With No Response to Frontline Induction Course [Phase 2]
A Phase 2 trial of Aezea (Cenersen) with chemotherapy for adults aged 55 and older with Acute Myeloid Leukemia who did not respond to frontl…
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CLINICAL_TRIALS withdrawal · 2014-04-07Clinical Trial Update: LENA-LMA-5:Lenalidomide in Acute Myeloid Leukemia (AML) [Phase 4]
A Phase 4 clinical trial (LENA-LMA-5) evaluating lenalidomide in acute myeloid leukemia has been terminated.