Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Minimal Residual Disease Evaluation on Cryopreserved Ovarian Fragments in Younger Patients Treated for Acute Myeloid Leukemia
This completed clinical trial evaluated minimal residual disease in cryopreserved ovarian tissue from younger patients treated for acute mye…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: GEN3014 Trial in Relapsed or Refractory Hematologic Malignancies [Phase 1, Phase 2]
Genmab's GEN3014 trial in relapsed or refractory hematologic malignancies (relapsed/refractory multiple myeloma, diffuse large B cell lympho…
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Comparing the Addition of an Anti-Cancer Drug, Pomalidomide, to the Usual Chemotherapy Treatment (Daunorubicin and Cytarabine Liposome) in Newly Diagnosed Acute Myeloid Leukemia With Myelodysplastic Syndrome-Related Changes [Phase 2]
Phase 2 trial evaluating adding pomalidomide to the standard liposomal daunorubicin/cytarabine chemotherapy in newly diagnosed acute myeloid…
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Off-the-shelf NK Cells + SCT for Myeloid Malignancies [Phase 2]
Phase 2 trial evaluating off-the-shelf natural killer (NK) cells in combination with stem cell transplantation for myeloid malignancies has …
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: Cytokine-Treated Veto Cells in Treating Patients With Hematologic Malignancies Following Stem Cell Transplant [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating cytokine-treated veto cells as an adoptive therapy after stem cell transplantation for various hematolog…
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: Plasma Dosage of Venetoclax in the Fup of AML Patients Treated With Aza + Ven [NA]
This clinical trial update reports on the plasma dosing of venetoclax in AML patients treated with azacitidine plus venetoclax. The study st…
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: A Phase I Study Investigating the Combination of the Menin Inhibitor Ziftomenib With Venetoclax and Gemtuzumab in Pediatric Patients With Acute Myeloid Leukemia [Phase 1]
A Phase I pediatric trial evaluating the combination of the menin inhibitor ziftomenib with venetoclax and gemtuzumab ozogamicin in acute my…
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: First-in-human Study of SAR443579 Infusion in Male and Female Children and Adult Participants With Relapsed or Refractory Acute Myeloid Leukemia (R/R AML), B-cell Acute Lymphoblastic Leukemia (B-ALL), High Risk-myelodysplasia (HR-MDS), or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) [Phase 1, Phase 2]
The first-in-human study of SAR443579 in children and adults with relapsed or refractory acute myeloid leukemia, acute lymphoblastic leukemi…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Sirolimus and Azacitidine in Treating Patients With High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia That is Recurrent or Not Eligible for Intensive Chemotherapy [Phase 2]
Phase 2 trial evaluating the combination of sirolimus and azacitidine in adults with high-risk myelodysplastic syndrome or acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: A Study to Assess Change in Disease State in Adult Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy in Switzerland and Austria Receiving Oral Venetoclax Tablets
Completed clinical trial assessing change in disease state in adults with Acute Myeloid Leukemia ineligible for intensive chemotherapy, eval…
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: Study of Single and Multiple Ascending Doses of ZE46-0134 in Healthy Volunteers [Phase 1]
Phase 1 dose-escalation study of ZE46-0134 in healthy volunteers has completed, with acute myeloid leukemia listed as the related condition.
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Pharmacokinetics, Safety, and Efficacy of ASTX727 in Combination With Venetoclax in Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
This clinical trial update describes pharmacokinetics, safety, and preliminary efficacy of the ASTX727 and venetoclax combination in patient…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Efficacy of Venetoclax Based Regimen in Prevention Relapse of Consecutive MRD Positive AML Patients [Phase 2]
Phase 2 trial of a venetoclax-based regimen to prevent relapse in MRD-positive acute myeloid leukemia was terminated.
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: The Oronasal Microbiota in Pediatric Oncology Patients
A completed clinical trial evaluating the oronasal microbiota in pediatric oncology patients, including those with acute myeloid leukemia an…
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CLINICAL_TRIALS trial_result · 2025-11-28Clinical Trial Update: Combination of HMA and Venetoclax With Posaconazole in Patients With Acute Myeloid Leukemia: A Study of Plasma Concentrations
This completed trial reports pharmacokinetic data for a combination of a hypomethylating agent with venetoclax and posaconazole in adults wi…
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: Study of Oral Venetoclax Tablets to Evaluate Adverse Events and Change in Disease Activity in Participants Above 19 Years of Age With Acute Myeloid Leukemia (AML)
A completed clinical trial evaluating oral venetoclax in adults with acute myeloid leukemia to assess adverse events and changes in disease …
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: A Clinical Study to Explore the Safety and Efficacy of CT0991 in Relapsed/Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial of CT0991 for relapsed/refractory acute myeloid leukemia has been suspended.
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Veliparib and Temozolomide in Treating Patients With Acute Leukemia [Phase 1]
Phase 1 study of veliparib plus temozolomide in adults with acute lymphoblastic leukemia or acute myeloid leukemia has completed enrollment,…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: VYxeoS Liposomal Italian Observational Study iN the Real Practice
A real-world observational study in Italy evaluating Vyxeos (CPX-351) for acute myeloid leukemia and its subtypes has completed.
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Safety and Efficacy of FT14 Conditioning for Allogeneic HSCT in Acute Myeloid Leukemia [Phase 2]
A Phase 2 trial is evaluating the safety and efficacy of FT14 conditioning for allogeneic hematopoietic stem cell transplantation in patient…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: A Study of MBG453 in Combination With Azacitidine and Venetoclax in AML Patients Unfit for Chemotherapy [Phase 2]
A Phase 2 study evaluating MBG453 in combination with azacitidine and venetoclax in AML patients unfit for chemotherapy has been terminated …
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer [Phase 1]
A Phase 1 trial evaluating natural killer cell therapy in combination with Interleukin-2 and the TGF-beta receptor I inhibitor vactosertib f…
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CLINICAL_TRIALS trial_result · 2025-11-10Clinical Trial Update: Haploidentical BMT With Post-Transplant Cyclophosphamide and Bendamustine [Phase 1]
A Phase 1 clinical trial evaluating a haploidentical bone marrow transplant using post-transplant cyclophosphamide and bendamustine has comp…
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CLINICAL_TRIALS trial_result · 2025-11-10Clinical Trial Update: Decitabine/Cedazuridine and Venetoclax in Combination With Ivosidenib or Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
Phase 1/2 clinical trials are evaluating a combination of decitabine/cedazuridine and venetoclax with either ivosidenib or enasidenib for re…
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: Testing Nivolumab to Prevent Disease From Coming Back After Treatment in Patients With Acute Myeloid Leukemia, REMAIN Trial [Phase 2]
This update reports the Phase 2 REMAIN trial results assessing nivolumab to prevent relapse in patients with acute myeloid leukemia after in…