Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: Efficacy Analysis of Comparison of CAMS（Chinese Academy of Medical Sciences）-2005 Trial and CAMS-2009 Trial for Pediatric Acute Myeloid Leukemia
This update reports an efficacy analysis comparing the CAMS-2005 and CAMS-2009 trials in pediatric acute myeloid leukemia, with the study st…
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: CLL-1/CD33 Targeted LCAR-AMDR Cells in Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 trial evaluating CLL-1/CD33-targeted LCAR-AMDR CAR-T cells for relapsed or refractory acute myeloid leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: LILRB4 STAR-T Cell Therapy for Monocytic Leukemia [NA]
A clinical trial evaluating LILRB4 STAR-T Cell Therapy for monocytic leukemia has completed its study for Acute Myeloid Leukemia and Chronic…
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: Natural Killer(NK) Cell Therapy in Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial update reports completion of a study evaluating natural killer cell therapy in adults with acute myeloid leukemia, …
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Ivosidenib (TIBSOVO®) Combined With Azacitidine According to Current SmPC
Clinical trial update noting completion of a study evaluating the combination of ivosidenib (TIBSOVO) with azacitidine in acute myeloid leuk…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: DR-18 for the Treatment of Relapsed or Persistent Acute Myeloid Leukemia or Myelodysplastic Syndrome After Hematopoietic Cell Transplantation, the DR. DREAM Trial [Phase 1]
Phase 1 trial DR-18 for relapsed or persistent acute myeloid leukemia or myelodysplastic syndrome after hematopoietic cell transplantation i…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: A Patient-Centered Communication Tool (UR-GOAL) Versus Usual Care for Older Patients With Acute Myeloid Leukemia, Their Caregivers, and Their Oncologists [NA]
This clinical trial updated results on UR-GOAL, a patient-centered communication tool, vs usual care for older adults with acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Olutasidenib Single Plus Combo Therapy in IDH1mut AML After Induction and Consolidation [Phase 1]
Phase 1 clinical trial evaluating the IDH1 inhibitor olutasidenib in a single-plus combo therapy for IDH1-mutant acute myeloid leukemia afte…
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: Cladribine Plus Homoharringtonine and Cytarabine Regimen (CHA) for de Novo Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating cladribine plus homoharringtonine and cytarabine (CHA) for de novo acute myeloid leukemia has completed, with the u…
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: Gilteritinib Plus VA Followed By Consolidation Chemotherapy in Newly Diagnosed FLT3-ITD+ AML [Phase 2]
Phase 2 trial evaluating gilteritinib plus VA (venetoclax and azacitidine) followed by consolidation chemotherapy in newly diagnosed FLT3-IT…
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: Phase I Trial of AZD1775 and Belinostat in Treating Patients With Relapsed or Refractory Myeloid Malignancies or Untreated Acute Myeloid Leukemia [Phase 1]
Phase I trial evaluating AZD1775 in combination with belinostat for relapsed or refractory myeloid malignancies or untreated acute myeloid l…
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: Mesenchymal Stem Cells in NPM1 Mutated Low Risk Acute Myeloid Leukemia: a Study of the Tumor Microenvironment and Its Contribution to the Outcome
A completed clinical trial evaluating mesenchymal stem cells in the tumor microenvironment of NPM1-mutated low-risk acute myeloid leukemia a…
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH [Phase 1]
Phase 1 study of HMPL-306 in advanced hematologic cancers with IDH mutation has been terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: A Safety, Tolerability and Efficacy Study of NC525 in Subjects With Advanced Myeloid Neoplasms [Phase 1]
Phase 1 safety, tolerability and preliminary efficacy study of NC525 in adults with advanced myeloid neoplasms has been terminated and resul…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Flotetuzumab for the Treatment of Relapsed or Refractory Advanced CD123-Positive Hematological Malignancies [Phase 1]
A Phase 1 trial evaluating flotetuzumab for relapsed or refractory CD123-positive hematologic malignancies has completed, providing initial …
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: Clinical Study of Anti-CLL1-CD33-NKG2D Bicephali CAR-T for Relapsed/Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating an Anti-CLL1-CD33-NKG2D bicephali CAR-T therapy for relapsed/refractory acute myeloid leukemia is list…
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: KPT-9274 in Patients With Relapsed and Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial evaluating KPT-9274 in patients with relapsed or refractory acute myeloid leukemia has completed, with results post…
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: Atovaquone (Mepron®) Combined With Conventional Chemotherapy for de Novo Acute Myeloid Leukemia (AML) [EARLY_Phase 1]
An early-phase study assessed adding atovaquone to conventional chemotherapy for newly diagnosed acute myeloid leukemia; the trial has compl…
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: Co-infusion of Treg-enriched Donor Lymphocytes With CD3-depleted Hematopoietic Stem Cell Graft to Prevent Graft-versus Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation Among Children With Hematologic Malignancies [Phase 2, Phase 3]
A Phase 2/3 clinical trial is evaluating co-infusion of regulatory T cell–enriched donor lymphocytes with a CD3-depleted hematopoietic stem …
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Dose-Escalation Study of Oral Administration of LP-108 as Monotherapy and in Combination With Azacitidine in Patients With Relapsed or Refractory MDS, CMML, or AML [Phase 1]
Phase 1 dose-escalation trial evaluating LP-108 as monotherapy and in combination with azacitidine in adults with relapsed or refractory mye…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Chimeric Antigen Receptor T Cell Redirected to Target CD4 Positive Relapsed Refractory Acute Myeloid Leukemia (AML ) as a Bridge to Allogeneic Stem Cell Transplant [Phase 1]
Phase 1 clinical trial evaluating a CD4-targeted CAR T cell therapy for relapsed/refractory acute myeloid leukemia as a bridge to allogeneic…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Trial of DFP-10917 vs Non-Intensive or Intensive Reinduction for AML Patients in 2nd/3rd/4th Salvage [Phase 3]
A Phase 3 trial evaluating DFP-10917 versus non-intensive or intensive reinduction for acute myeloid leukemia in 2nd to 4th salvage was term…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Phase 1 Study of UniCAR02-T-CD123 in Patients With Selected CD123 Positive Hematologic Malignancies [Phase 1]
A Phase 1 study of UniCAR02-T-CD123 in CD123-positive hematologic malignancies has been terminated, with Acute Myeloid Leukemia included amo…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Dendritic Cell/AML Fusion Cell Vaccine Following Allogeneic Transplantation in AML Patients [Phase 1]
Phase 1 clinical trial of a dendritic cell/AML fusion cell vaccine given after allogeneic transplantation in acute myeloid leukemia patients…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Daunorubicin and Cytarabine With or Without Uproleselan in Treating Older Adult Patients With Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating daunorubicin and cytarabine with or without uproleselan in older adults with acute myeloid leukemia un…