Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-01-03Clinical Trial Update: Azacitidine + Lenalidomide Combo in the Elderly With Previously Treated AML & High-Risk MDS [Phase 2]
Phase 2 trial update of azacitidine plus lenalidomide in elderly patients with previously treated acute myeloid leukemia and high-risk myelo…
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CLINICAL_TRIALS trial_result · 2018-01-02Clinical Trial Update: Cyclophosphamide and Busulfan Followed by Donor Stem Cell Transplant in Treating Patients With Myelofibrosis, Acute Myeloid Leukemia, or Myelodysplastic Syndrome [NA]
Clinical trial update on cyclophosphamide and busulfan followed by donor stem cell transplant for myelofibrosis, AML, or myelodysplastic syn…
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CLINICAL_TRIALS trial_result · 2017-12-11Clinical Trial Update: A Study of RO6870810/TEN-010 in Participants With Acute Myeloid Leukemia and Myelodysplastic Syndrome [Phase 1]
Phase 1 study of RO6870810/TEN-010 in patients with Acute Myeloid Leukemia and Myelodysplastic Syndromes has completed.
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CLINICAL_TRIALS trial_result · 2017-12-08Clinical Trial Update: Decitabine and Selinexor in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
This Phase 1 trial updates the safety and preliminary activity of decitabine combined with selinexor in patients with relapsed or refractory…
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CLINICAL_TRIALS trial_result · 2017-12-08Clinical Trial Update: Rasburicase and Allopurinol in Treating Patients With Hematologic Malignancies [Phase 2]
Phase 2 trial evaluating rasburicase and allopurinol in adults with hematologic malignancies; the study was terminated with results posted i…
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CLINICAL_TRIALS trial_result · 2017-12-06Clinical Trial Update: Evaluation of "Dose-dense Therapy" by S-HAM in Comparison to Conventionally Timed Double Induction in Patients With Acute Myeloid Leukemia (AML) [Phase 3]
A Phase 3 trial comparing dose-dense S-HAM therapy to conventionally timed double induction in acute myeloid leukemia has completed. The upd…
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CLINICAL_TRIALS trial_result · 2017-12-06Clinical Trial Update: MEK Inhibitor MEK162, Idarubicin, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 trial evaluating a MEK inhibitor (MEK162) in combination with idarubicin and cytarabine for adults with relapsed or refractory acu…
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CLINICAL_TRIALS trial_result · 2017-12-05Clinical Trial Update: AHN-12 Biodistribution in Advanced Leukemia [Phase 1]
A Phase 1 trial of the investigational agent AHN-12 focusing on biodistribution in advanced leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2017-12-04Clinical Trial Update: Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant [Phase 3]
Phase 3 trial update on graft-versus-host disease prophylaxis in patients with hematologic malignancies undergoing unrelated donor periphera…
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CLINICAL_TRIALS trial_result · 2017-12-04Clinical Trial Update: Evaluating Cell Damage in Patients With Acute Myeloid Leukemia, Myelodysplastic Syndromes, or Fanconi Anemia; in Patients Who Were Exposed to Alkylating Agents; and in Healthy Volunteers
A completed clinical trial evaluating cell damage from alkylating agents in patients with acute myeloid leukemia, myelodysplastic syndromes,…
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CLINICAL_TRIALS trial_result · 2017-11-30Clinical Trial Update: An Open Label Phase II Pharmacokinetic and Pharmacodynamic Assessment of the Potential for QTc Prolongation Following First Induction Treatment With CPX-351 (Cytarabine:Daunorubicin) Liposome Injection in Acute Leukemias and MDS Patients [Phase 2]
This Phase 2 open-label pharmacokinetic/pharmacodynamic trial evaluated CPX-351 (cytarabine:daunorubicin liposome injection) for potential Q…
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Maintenance Therapy With Ceplene® (Histamine) and IL-2 on Immune Response and MRD in Acute Myeloid Leukemia [Phase 4]
Phase 4 clinical trial evaluating maintenance therapy with Ceplene (histamine dihydrochloride) and interleukin-2 in acute myeloid leukemia t…
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Donor Lymphocyte Infusion (DLI) for Relapsed (Post Transplant) Leukemia [NA]
The document reports the completion of a clinical trial evaluating donor lymphocyte infusion for relapsed leukemia after transplantation acr…
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CLINICAL_TRIALS trial_result · 2017-11-22Clinical Trial Update: Treatment With Low-Dose Cytarabine in Elderly Patients (Age 70 Years or Older) With Acute Myeloid Leukemia: A Single Institution Experience.
This clinical trial update summarizes results from a single-institution experience using low-dose cytarabine in elderly patients (70 years o…
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CLINICAL_TRIALS trial_result · 2017-11-20Clinical Trial Update: ABT-348 as Monotherapy and in Combination With Azacitidine to Treat Advanced Hematologic Malignancies [Phase 1]
A Phase 1 trial evaluated ABT-348 as a standalone therapy and in combination with azacitidine for advanced hematologic malignancies; the stu…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Idarubicin, Cytarabine, and Pravastatin Sodium in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes [NA]
This clinical trial evaluated a combination of idarubicin, cytarabine, and pravastatin sodium in adults with acute myeloid leukemia or myelo…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Gluten Free Diet in Diminishing Side Effects Patients With Acute Myeloid Leukemia Undergoing Induction Chemotherapy [Phase 2]
A Phase 2 clinical trial testing whether a gluten-free diet reduces side effects in patients with acute myeloid leukemia undergoing inductio…
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: Lenalidomide in Acute Leukemias and Chronic Lymphocytic Leukemia. [Phase 1]
This update reports the completion of a Phase 1 trial evaluating lenalidomide in acute myeloid leukemia, acute lymphoblastic leukemia, and c…
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Eltrombopag Treatment of Thrombocytopenia in Subjects With Advanced Myelodysplastic Syndrome (MDS) or Secondary Acute Myeloid Leukemia After MDS (sAML/MDS) [Phase 1]
A completed Phase 1 trial evaluating eltrombopag for treating thrombocytopenia in patients with advanced myelodysplastic syndromes or second…
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Combination Study of GSK1120212 With Gemcitabine in Subjects With Solid Tumors [Phase 1]
Phase 1 trial evaluating the combination of trametinib (GSK1120212) and gemcitabine in subjects with solid tumors; the study has completed.
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CLINICAL_TRIALS trial_result · 2017-11-08Clinical Trial Update: T-cell Depleted Alternative Donor Transplantation [Phase 2]
Phase 2 clinical trial of T-cell depleted alternative donor transplantation for acute leukemias and related conditions was terminated with r…
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: Study Evaluating Orally Administered AMG 900 in Adult Subjects With Acute Myeloid Leukemia [Phase 1]
An early-phase trial evaluating orally administered AMG 900 in adults with acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2017-11-01Clinical Trial Update: Microtransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger Patients [Phase 2]
Phase 2 clinical trial of microtransplantation for refractory or relapsed hematologic malignancies in younger patients was terminated, with …
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CLINICAL_TRIALS trial_result · 2017-10-17Clinical Trial Update: CD123 Redirected Autologous T Cells for AML [EARLY_Phase 1]
An early-phase 1 trial assessing CD123-targeted autologous T cells for relapsed or refractory acute myeloid leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2017-10-02Clinical Trial Update: Phase III Study of CPX-351 Versus 7+3 in Patients 60-75 Years Old With Untreated High Risk (Secondary) Acute Myeloid Leukemia [Phase 3]
Phase III trial comparing CPX-351 to the 7+3 regimen in untreated high-risk secondary acute myeloid leukemia in patients aged 60-75 has comp…