Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-06-10Clinical Trial Update: Decitabine Based Chemotherapy Followed by Haploidentical Lymphocyte Infusion for Elderly Patients With AML [Phase 2]
Phase 2 trial evaluating decitabine-based chemotherapy followed by haploidentical lymphocyte infusion in elderly AML patients has completed.
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CLINICAL_TRIALS trial_result · 2019-06-07Clinical Trial Update: A Study of Azacitidine for Patients With Int/High -Risk MDS and AML-MRC [Phase 3]
Phase 3 trial evaluating azacitidine in patients with intermediate/high-risk myelodysplastic syndromes and AML with myelodysplasia-related c…
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CLINICAL_TRIALS trial_result · 2019-05-22Clinical Trial Update: Decitabine and Total-Body Irradiation Followed By Donor Bone Marrow Transplant and Cyclophosphamide in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating decitabine with total-body irradiation followed by donor bone marrow transplant and cyclophosphamide for relapsed o…
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CLINICAL_TRIALS trial_result · 2019-05-17Clinical Trial Update: Study to Determine Safety, Pharmacokinetics and Efficacy of GMI-1271 in Combination With Chemotherapy in AML [Phase 1, Phase 2]
Clinical trial update on GMI-1271 in combination with chemotherapy for acute myeloid leukemia (AML) completed Phase 1/2 studies to assess sa…
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CLINICAL_TRIALS trial_result · 2019-05-10Clinical Trial Update: Plerixafor and Clofarabine in Frontline Treatment of Elderly Patients With Acute Myelogenous Leukemia (AML) [Phase 1, Phase 2]
Phase 1/2 clinical trial of plerixafor and clofarabine as frontline therapy in elderly AML patients; trial terminated with posted results in…
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CLINICAL_TRIALS trial_result · 2019-05-07Clinical Trial Update: CD3/CD19 Depleted or CD3 Depleted/CD56 Selected Haploidentical Donor Natural Killer (NK) Cell Based Therapy for AML Patients Not in CR [NA]
Clinical trial update for NK cell therapy in AML patients not in complete remission; the study is terminated with posted results.
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CLINICAL_TRIALS trial_result · 2019-05-06Clinical Trial Update: Dasatinib as Therapy for Myeloproliferative Disorders (MPDs) [Phase 2]
Phase 2 trial evaluating dasatinib for myeloproliferative disorders; the study has completed and results were posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-05-01Clinical Trial Update: Safety and Efficacy of BL-8040 for the Mobilization of Donor Hematopoietic Stem Cells and Allogeneic Transplantation in Patients With Advanced Hematological Malignancies [Phase 2]
Phase 2 clinical trial evaluating BL-8040 for mobilizing donor hematopoietic stem cells to enable allogeneic transplantation in patients wit…
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CLINICAL_TRIALS trial_result · 2019-04-23Clinical Trial Update: DT388IL3 Fusion Protein in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes [Phase 1, Phase 2]
Clinical trial update for DT388IL3 fusion protein in acute myeloid leukemia and myelodysplastic syndromes (Phase 1/2) completed with results…
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CLINICAL_TRIALS trial_result · 2019-04-16Clinical Trial Update: Study of Palbociclib in MLL-rearranged Acute Leukemias [Phase 1, Phase 2]
A clinical trial investigating palbociclib in MLL-rearranged acute leukemias (AML and ALL) across Phase 1 and Phase 2 ongoing with currently…
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CLINICAL_TRIALS trial_result · 2019-04-03Clinical Trial Update: Transplantation of Umbilical Cord Blood Following Chemotherapy for Blood Cancers [Phase 1, Phase 2]
Phase 1/2 trial evaluating transplantation of umbilical cord blood after chemotherapy for acute blood cancers; trial terminated with results…
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CLINICAL_TRIALS trial_result · 2019-03-20Clinical Trial Update: Study of US-ATG-F to Prevent Chronic Graft Versus Host Disease (GVHD) [Phase 3]
A Phase 3 trial evaluating US-ATG-F to prevent chronic graft-versus-host disease in hematologic malignancy patients has completed with resul…
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CLINICAL_TRIALS trial_result · 2019-03-19Clinical Trial Update: Sequential Intensive Chemotherapy Followed by RIC for Refractory and Relapse AML [Phase 2]
Phase 2 clinical trial evaluating sequential intensive chemotherapy followed by reduced-intensity conditioning for refractory and relapsed a…
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CLINICAL_TRIALS trial_result · 2019-03-18Clinical Trial Update: A Study Of PF-06747143, As Single Agent Or In Combination With Standard Chemotherapy In Adult Patients With Acute Myeloid Leukemia [Phase 1]
Phase 1 study of PF-06747143 as a single agent or with standard chemotherapy in adult acute myeloid leukemia was terminated with results pos…
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CLINICAL_TRIALS trial_result · 2019-03-05Clinical Trial Update: A Study of E6201 for the Treatment of Advanced Hematologic Malignancies With FLT3 and/or Ras Mutations [Phase 1, Phase 2]
Clinical trial update for E6201 in advanced hematologic malignancies with FLT3 and/or Ras mutations (Phase 1/2) shows terminated status; res…
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CLINICAL_TRIALS trial_result · 2019-02-28Clinical Trial Update: An Efficacy and Safety Study of Decitabine (DACOGEN) Plus Talacotuzumab (JNJ-56022473; Anti CD123) Versus Decitabine (DACOGEN) Alone in Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy [Phase 2, Phase 3]
Phase 2/3 trial evaluating decitabine with talacotuzumab versus decitabine alone in adults with acute myeloid leukemia ineligible for intens…
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CLINICAL_TRIALS trial_result · 2019-02-28Clinical Trial Update: Study of Combination Ruxolitinib and Decitabine Treatment for Accelerated Phase MPN or Post-MPN AML [Phase 1, Phase 2]
A trial evaluating the combination of ruxolitinib and decitabine in accelerated phase myeloproliferative neoplasms or post-MPN acute myeloid…
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CLINICAL_TRIALS trial_result · 2019-02-26Clinical Trial Update: Pilot Study Evaluating Safety & Efficacy of DCBT: NiCord® & UNM CBU to Patients With Hematological Malignancies [Phase 1, Phase 2]
A pilot Phase 1/2 study evaluating safety and efficacy of NiCord and UNM CBU in patients with various hematologic malignancies has completed…
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CLINICAL_TRIALS trial_result · 2019-02-21Clinical Trial Update: CAMELLIA: Anti-CD47 Antibody Therapy in Haematological Malignancies [Phase 1]
This update reports the completion of a Phase 1 study of CAMELLIA, an anti-CD47 antibody therapy, in hematologic malignancies.
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CLINICAL_TRIALS trial_result · 2019-02-20Clinical Trial Update: Dose Escalation Study Investigating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics of ASP2215 in Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
Update on a dose-escalation study of gilteritinib (ASP2215) assessing safety, tolerability, and pharmacokinetics/pharmacodynamics in relapse…
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CLINICAL_TRIALS trial_result · 2019-02-18Clinical Trial Update: Combination 5-azacitidine and Gemtuzumab Ozogamicin Therapy for Treatment of Relapsed Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating the safety and preliminary efficacy of combining azacitidine with gemtuzumab ozogamicin in relapsed a…
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CLINICAL_TRIALS trial_result · 2019-02-12Clinical Trial Update: A Study of AC220 Given After Transplant in Subjects With Acute Myeloid Leukemia (AML) [Phase 1]
Completed Phase 1 study evaluating quizartinib (AC220) given after stem cell transplant in patients with acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2019-02-12Clinical Trial Update: Phase 1 Study of Quizartinib [Phase 1]
The document describes the completion of a Phase 1 trial of quizartinib in relapsed or refractory acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2019-02-12Clinical Trial Update: A Study to Assess AC220 Given in Combination With Induction and Consolidation Therapy in Newly Diagnosed Acute Myeloid Leukemia (AML) [Phase 1]
Phase 1 study evaluating AC220 (quizartinib) in combination with induction and consolidation therapy for newly diagnosed acute myeloid leuke…
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CLINICAL_TRIALS trial_result · 2019-02-12Clinical Trial Update: Bridging Study to Eliminate Presence of MRD for Acute Leukemia Before HCT [Phase 2]
Phase 2 bridging study evaluating elimination of minimal residual disease before hematopoietic cell transplantation in acute leukemia; study…