Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-05-21Clinical Trial Update: Pembrolizumab and Decitabine for Refractory or Relapsed Acute Myeloid Leukemia [Phase 1, Phase 2]
Clinical trial assessing pembrolizumab with decitabine in relapsed or refractory acute myeloid leukemia has completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-05-04Clinical Trial Update: An Efficacy and Safety Study of Azacitidine Subcutaneous in Combination With Durvalumab (MEDI4736) in Previously Untreated Adults With Higher-Risk Myelodysplastic Syndromes (MDS) or in Elderly Patients With Acute Myeloid Leukemia (AML) [Phase 2]
Phase 2 trial evaluating azacitidine plus durvalumab in untreated higher-risk myelodysplastic syndromes or elderly AML patients, with comple…
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CLINICAL_TRIALS trial_result · 2020-05-04Clinical Trial Update: Treosulfan-based Conditioning in Paediatric Patients With Haematological Malignancies [Phase 2]
Phase 2 trial update evaluating treosulfan-based conditioning in pediatric patients with hematological malignancies.
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CLINICAL_TRIALS trial_result · 2020-05-01Clinical Trial Update: Midostaurin and Azacitidine in Treating Elderly Patients With Acute Myelogenous Leukemia [Phase 1, Phase 2]
A midostaurin and azacitidine trial in elderly patients with untreated acute myeloid leukemia completed phases 1 and 2 with results posted i…
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CLINICAL_TRIALS trial_result · 2020-04-27Clinical Trial Update: Bioelectrical Impedance Measurement for Predicting Treatment Outcome in Patients With Newly Diagnosed Acute Leukemia [NA]
A completed clinical trial evaluating bioelectrical impedance measurements to predict treatment outcomes in newly diagnosed acute leukemia p…
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CLINICAL_TRIALS trial_result · 2020-04-27Clinical Trial Update: A Clinical Trail of Demethylation Drug Combined With Chemotherapy in Intermediate-risk AML [Phase 2]
Phase 2 clinical trial evaluating a demethylation drug combined with chemotherapy in intermediate-risk acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2020-04-24Clinical Trial Update: A Phase I Study of AC220 in Patients With Relapsed/Refractory Acute Myeloid Leukemia Regardless of FLT3 Status [Phase 1]
Phase I study of AC220 (trastuz? actually AC220 is quizartinib, a FLT3 inhibitor) in relapsed/refractory AML regardless of FLT3 status; comp…
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CLINICAL_TRIALS trial_result · 2020-04-24Clinical Trial Update: Selinexor in Combination With Fludarabine and Cytarabine in Patients With Refractory or Relapsed Acute Myeloid Leukemia [Phase 2]
A phase 2 clinical trial evaluating selinexor in combination with fludarabine and cytarabine for refractory or relapsed acute myeloid leukem…
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CLINICAL_TRIALS trial_result · 2020-04-24Clinical Trial Update: CD38-targeted Chimeric Antigen Receptor T Cell (CART) in Relapesd or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
Clinical trial update for CD38-targeted CAR-T therapy in relapsed or refractory acute myeloid leukemia (Phase 1/Phase 2).
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CLINICAL_TRIALS trial_result · 2020-04-20Clinical Trial Update: Combined PD1 Inhibitor and Decitabine in Elderly Patients With Relapse and Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 trial assessing the combination of a PD-1 inhibitor with decitabine for elderly patients with relapse/refractory acute myeloid leuke…
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CLINICAL_TRIALS trial_result · 2020-04-16Clinical Trial Update: Clofarabine and Low-Dose Total-Body Irradiation in Treating Patients With Acute Myeloid Leukemia Undergoing Donor Peripheral Blood Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating clofarabine with low-dose total-body irradiation as conditioning for donor peripheral blood stem cell tran…
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CLINICAL_TRIALS trial_result · 2020-04-15Clinical Trial Update: Decitabine for Older or Unfit Patients With Acute Myeloid Leukemia (AML) [Phase 2]
Phase 2 trial update of decitabine in older or unfit patients with acute myeloid leukemia (AML) has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-04-06Clinical Trial Update: Azacytidine (Vidaza®) Versus Fludarabine and Cytarabine (Fluga Scheme) in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 3]
A Phase 3 trial comparing azacitidine (Vidaza) versus fludarabine and cytarabine (Fluga scheme) in elderly patients with newly diagnosed acu…
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CLINICAL_TRIALS trial_result · 2020-04-02Clinical Trial Update: King's Invasive Aspergillosis Study II [Phase 4]
A Phase 4 clinical trial update for King's Invasive Aspergillosis Study II (NCT02875743) from King's College Hospital NHS Trust, with condit…
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CLINICAL_TRIALS trial_result · 2020-03-31Clinical Trial Update: Phase I/II, Study of Selective Inhibitor of Nuclear Export (SINE) Selinexor (KPT-330) + Sorafenib in Acute Myeloid Leukemia [Phase 1, Phase 2]
Phase I/II trial evaluating Selinexor (KPT-330) in combination with Sorafenib for acute myeloid leukemia has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-03-30Clinical Trial Update: Combination of Sorafenib and Omacetaxine Mepesuccinate in Newly Diagnosed or Relapsed/Refractory AML Carrying FLT3-ITD [Phase 2]
A Phase 2 trial evaluating the combination of sorafenib and omacetaxine mepesuccinate in newly diagnosed or relapsed/refractory acute myeloi…
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CLINICAL_TRIALS trial_result · 2020-03-30Clinical Trial Update: Using Sorafenib as a Salvage Treatment for Relapsed or Refractory Acute Myeloid Leukemia Carrying FLT3-ITD [Phase 2]
Phase 2 clinical trial evaluating sorafenib as salvage therapy for relapsed or refractory acute myeloid leukemia with FLT3-ITD mutation.
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CLINICAL_TRIALS trial_result · 2020-03-23Clinical Trial Update: Leukemia Stem Cell Detection in Acute Myeloid Leukemia [Phase 3]
Phase 3 trial update on detecting leukemia stem cells in acute myeloid leukemia; trial status is terminated with results posted.
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CLINICAL_TRIALS trial_result · 2020-03-19Clinical Trial Update: 10-day Decitabine, Fludarabine and 2 Gray TBI as Conditioning Strategy for Poor and Very Poor Risk AML in CR1 [Phase 2]
A Phase 2 clinical trial evaluates 10-day decitabine, fludarabine, and 2 Gy total body irradiation as a conditioning regimen for poor-risk A…
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CLINICAL_TRIALS trial_result · 2020-03-19Clinical Trial Update: Genomics-Based Target Therapy for Children With Relapsed or Refractory Malignancy [Phase 2]
Phase 2 trial update exploring genomics-based targeted therapy for children with relapsed or refractory malignancies.
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CLINICAL_TRIALS trial_result · 2020-03-17Clinical Trial Update: Decitabine With GCLAM for Adults With Newly Diagnosed, Relapsed, or Refractory AML or High-Risk MDS [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating decitabine with the GCLAM regimen in adults with newly diagnosed, relapsed, or refractory acute myeloi…
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CLINICAL_TRIALS trial_result · 2020-03-13Clinical Trial Update: Study of CLAG + Selinexor in Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
Phase 1/2 study of CLAG plus selinexor in relapsed or refractory acute myeloid leukemia completed with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-03-10Clinical Trial Update: Decitabine Plus mBU/CY for High Risk Acute Leukemia With MRD Pre-HSCT [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating decitabine in combination with mBU/CY for high-risk acute leukemia with minimal residual disease before …
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CLINICAL_TRIALS trial_result · 2020-03-06Clinical Trial Update: Entospletinib (ENTO) as Monotherapy and in Combination With Chemotherapy in Japanese Adults [Phase 1]
Phase 1 trial updates Entospletinib as monotherapy and in combination with chemotherapy in Japanese adults with hematologic malignancies, in…
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CLINICAL_TRIALS trial_result · 2020-03-04Clinical Trial Update: MRD-directed Therapy for Low-risk and Intermediate-risk AML. [Phase 2, Phase 3]
Phase 2/3 trial investigating MRD-directed therapy for low-risk and intermediate-risk acute myeloid leukemia.