Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-05-04Clinical Trial Update: DEPLETHINK - LymphoDEPLEtion and THerapeutic Immunotherapy With NKR-2 [Phase 1, Phase 2]
Clinical trial update for DEPLETHINK (NKR-2) reporting Phase 1/Phase 2 results in AML and MDS; trial status completed.
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CLINICAL_TRIALS trial_result · 2021-04-28Clinical Trial Update: The Use of Decitabine as Induction Therapy for Acute Myeloid Leukemia With Complex and/or Monosomal Karyotype [Phase 2]
Phase 2 trial update on using decitabine as induction therapy for acute myeloid leukemia with complex and/or monosomal karyotype.
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CLINICAL_TRIALS trial_result · 2021-04-26Clinical Trial Update: Vidaza and Valproic Acid Post Allogeneic Transplant for High Risk AML and MDS [Phase 2]
Phase 2 clinical trial evaluating Vidaza (azacitidine) and valproic acid after allogeneic transplant in high-risk AML and MDS.
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CLINICAL_TRIALS trial_result · 2021-04-20Clinical Trial Update: MEK Inhibitor 162 Relapsed and/or Refractory Acute Myeloid Leukemia (AML) and Poor Prognosis, Not Suitable for or Unwilling to Receive Standard Therapy [Phase 1, Phase 2]
Phase 1/2 trial of MEK inhibitor 162 in relapsed/refractory acute myeloid leukemia with poor prognosis; the study terminated with posted res…
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CLINICAL_TRIALS trial_result · 2021-04-13Clinical Trial Update: Busulfan and Cyclophosphamide Followed By ALLO BMT [NA]
Clinical trial update for busulfan and cyclophosphamide followed by allogeneic stem cell transplant in acute leukemias; study is terminated …
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CLINICAL_TRIALS trial_result · 2021-04-08Clinical Trial Update: Pilot Clinical Trial of Pazopanib in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) or at Initial Diagnosis When no Intensive Treatment is Possible [Phase 2]
Phase 2 pilot trial of pazopanib in patients with relapsed/refractory AML or newly diagnosed where intensive treatment isn’t possible comple…
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CLINICAL_TRIALS trial_result · 2021-04-01Clinical Trial Update: A Phase 2 Study of Venetoclax in Combination With Low-dose HHT, G-CSF, and AZA as First-line Treatment for Newly Diagnosed Elderly AML Patients Unfit for Intensive Chemotherapy [Phase 2]
Phase 2 study evaluating venetoclax with low-dose hypomethylating agent, G-CSF, and azacitidine as first-line treatment for newly diagnosed …
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CLINICAL_TRIALS trial_result · 2021-03-26Clinical Trial Update: A Phase 2 Trial to Evaluate the Efficacy and Safety of OCV-501 in Elderly Patients With Acute Myeloid Leukemia [Phase 2]
A Phase 2 trial assessing efficacy and safety of OCV-501 in elderly patients with Acute Myeloid Leukemia has completed and posted results.
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CLINICAL_TRIALS trial_result · 2021-03-24Clinical Trial Update: Early Palliative Care for Patients With Haematological Malignancies [Phase 3]
Phase 3 clinical trial update on early palliative care for patients with hematologic malignancies including acute myeloid leukemia and myelo…
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CLINICAL_TRIALS trial_result · 2021-03-22Clinical Trial Update: Early Allogeneic Hematopoietic Cell Transplantation in Treating Patients With Relapsed or Refractory High-Grade Myeloid Neoplasms [Phase 2]
Phase 2 trial evaluating early allogeneic hematopoietic cell transplantation for patients with relapsed or refractory high-grade myeloid neo…
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CLINICAL_TRIALS trial_result · 2021-03-22Clinical Trial Update: Allogenic Stem Cell Transplantation for Children, Adolescents and Young Adults With Relapsed or Refractory AML [Phase 3]
Phase 3 trial assessing allogeneic stem cell transplantation for children and young adults with relapsed or refractory acute myeloid leukemi…
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CLINICAL_TRIALS trial_result · 2021-03-18Clinical Trial Update: The Rapid Study: Randomized Phase II Study To Expedite Allogeneic Transplant With Immediate Haploidentical Plus Unrelated Cord Donor Search Versus Matched Unrelated Donor Search For AML And High-Risk MDS Patients [Phase 2]
Phase II randomized trial evaluating rapid haploidentical plus unrelated cord donor search versus matched unrelated donor search for AML and…
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CLINICAL_TRIALS trial_result · 2021-03-17Clinical Trial Update: Standard of Care +/- Midostaurin to Prevent Relapse Post Stem Cell Transplant in Patients With FLT3-ITD Mutated AML [Phase 2]
Phase 2 trial update evaluating Standard of Care with or without Midostaurin to prevent relapse after stem cell transplant in FLT3-ITD mutat…
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CLINICAL_TRIALS trial_result · 2021-03-16Clinical Trial Update: Safety and Activity of Digoxin With Decitabine in Adult AML and MDS [Phase 1, Phase 2]
Phase 1/2 trial evaluating safety and activity of digoxin in combination with decitabine for adults with acute myeloid leukemia and myelodys…
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CLINICAL_TRIALS trial_result · 2021-03-08Clinical Trial Update: A Phase I Study of OCV-501 in Acute Myeloid Leukemia Patients [Phase 1]
Phase I trial update of OCV-501 in acute myeloid leukemia has completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-03-05Clinical Trial Update: A Combination Study of PF-04449913 (Glasdegib) and Azacitidine In Untreated MDS, AML and CMML Patients [Phase 1]
A Phase 1 trial evaluating the combination of glasdegib (PF-04449913) with azacitidine in untreated myelodysplastic syndrome, acute myeloid …
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CLINICAL_TRIALS trial_result · 2021-03-05Clinical Trial Update: Phase 1 Study of SGI-110 in Patients With Acute Myeloid Leukemia [Phase 1]
Phase 1 trial update of SGI-110 in patients with acute myeloid leukemia has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-03-05Clinical Trial Update: Outpatient Induction Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome [NA]
Clinical trial update for outpatient induction chemotherapy in adults with Acute Myeloid Leukemia or Myelodysplastic Syndrome; trial complet…
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CLINICAL_TRIALS trial_result · 2021-03-02Clinical Trial Update: Study of OCV-501 in Patients With Acute Myeloid Leukemia (AML) (Extension From Study 311-10-001) [Phase 1]
Phase 1 extension study of OCV-501 in acute myeloid leukemia has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-02-26Clinical Trial Update: Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial evaluating treosulfan, fludarabine phosphate, and total-body irradiation as conditioning before donor stem cell transplant in …
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CLINICAL_TRIALS trial_result · 2021-02-25Clinical Trial Update: Phase 1b/2 Safety and Efficacy of APR-246 w/Azacitidine for tx of TP53 Mutant Myeloid Neoplasms [Phase 1, Phase 2]
Phase 1b/2 trial assessing APR-246 plus azacitidine in TP53-mutant myeloid neoplasms completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-02-24Clinical Trial Update: Bortezomib and Doxil for the Treatment of Patients With Acute Myelogenous Leukemia [Phase 2]
A Phase 2 clinical trial evaluating bortezomib and Doxil for acute myeloid leukemia has completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-02-21Clinical Trial Update: Haploidentical Stem Cell Transplantation for Children With Therapy Resistant Leukemia [Phase 2]
Phase 2 clinical trial evaluating haploidentical stem cell transplantation for children with therapy-resistant leukemia (ALL and AML) has be…
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CLINICAL_TRIALS trial_result · 2021-02-09Clinical Trial Update: Safety and Efficacy Study of Pracinostat With Azacitadine in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (AML) [Phase 2]
Phase 2 safety and efficacy study of pracinostat with azacitidine in elderly patients with newly diagnosed acute myeloid leukemia completed …
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CLINICAL_TRIALS trial_result · 2021-02-08Clinical Trial Update: A Study of ARRY-520 in Patients With Advanced Myeloid Leukemia [Phase 1, Phase 2]
Phase 1/2 study of ARRY-520 in advanced myeloid leukemia and myelodysplastic syndromes has completed.