Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-02-21Clinical Trial Update: A Study Evaluating the Safety and Pharmacokinetics of Atezolizumab Administered in Combination With Hu5F9-G4 to Patients With Relapsed and/or Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 trial evaluating safety and pharmacokinetics of atezolizumab with Hu5F9-G4 in relapsed/refractory acute myeloid leukemia; study term…
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CLINICAL_TRIALS trial_result · 2022-02-09Clinical Trial Update: Study of Vosaroxin and Decitabine in Older Patients With Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome [Phase 1, Phase 2]
A phase 1/2 trial evaluating vosaroxin with decitabine in older adults with acute myeloid leukemia and high-risk myelodysplastic syndrome ha…
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CLINICAL_TRIALS trial_result · 2022-01-25Clinical Trial Update: PF-04449913 For Patients With Acute Myeloid Leukemia at High Risk of Relapse After Donor Stem Cell Transplant [Phase 2]
Phase 2 clinical trial update for PF-04449913 in adults with acute myeloid leukemia at high risk of relapse after donor stem cell transplant…
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CLINICAL_TRIALS trial_result · 2022-01-19Clinical Trial Update: Study of CAR T-cell Therapy in Acute Myeloid Leukemia and Multiple Myeloma [Phase 1, Phase 2]
A phase 1/2 clinical trial of CAR T-cell therapy for acute myeloid leukemia and multiple myeloma has terminated with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-01-03Clinical Trial Update: Aza With or Without ATRA in Newly Diagnosed Unfit AML or Intermediate,High or Very High Risk MDS [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial evaluating azacitidine with or without ATRA in newly diagnosed unfit acute myeloid leukemia or intermediate…
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CLINICAL_TRIALS trial_result · 2021-12-30Clinical Trial Update: Anti-FLT3 CAR T-cell Therapy in FLT3 Positive Relapsed/Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
An update on an anti-FLT3 CAR T-cell therapy being evaluated in FLT3-positive relapsed/refractory acute myeloid leukemia across Phase 1 and …
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CLINICAL_TRIALS trial_result · 2021-12-21Clinical Trial Update: Evaluating the Efficacy and Safety of Bemcentinib in Patients With Myelodysplastic Syndromes [Phase 2]
Phase 2 clinical trial evaluating bemcentinib for myelodysplastic syndromes and related conditions has completed.
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CLINICAL_TRIALS trial_result · 2021-12-16Clinical Trial Update: Fludarabine-IV Busulfan ± Clofarabine and Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) [Phase 3]
Phase 3 trial evaluating fludarabine-IV busulfan with or without clofarabine as conditioning for allogeneic hematopoietic stem cell transpla…
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CLINICAL_TRIALS trial_result · 2021-12-08Clinical Trial Update: Vitamin D Effect on A Disintegrin-like And Metalloprotease Thrombospondin1 Motif 13& Interleukin 6 in Leukemia [Phase 1, Phase 2]
Phase 1/2 trial exploring vitamin D effects on ADAMTS13 and interleukin-6 pathways in acute myeloid leukemia with vitamin D deficiency; stud…
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CLINICAL_TRIALS trial_result · 2021-12-03Clinical Trial Update: PD-1 Inhibitor Combined With Azacytidine and Homoharringtonine，Cytarabine, G-CSF for Refractory or Relapsed AML [Phase 3]
A Phase 3 trial evaluating a PD-1 inhibitor combined with azacytidine, homoharringtonine, cytarabine, and G-CSF for refractory or relapsed a…
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CLINICAL_TRIALS trial_result · 2021-12-02Clinical Trial Update: JNJ-40346527 in Treating Participants With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial of JNJ-40346527 in relapsed or refractory acute myeloid leukemia has terminated with posted results.
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CLINICAL_TRIALS trial_result · 2021-12-01Clinical Trial Update: Double Cord Versus Haploidentical (BMT CTN 1101) [Phase 3]
Phase 3 trial comparing double cord blood transplantation versus haploidentical transplant in acute leukemias completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-11-19Clinical Trial Update: Volasertib in Combination With Low-dose Cytarabine in Patients Aged 65 Years and Above With Previously Untreated Acute Myeloid Leukaemia, Who Are Ineligible for Intensive Remission Induction Therapy (POLO-AML-2) [Phase 3]
Phase 3 trial POLO-AML-2 evaluated volasertib plus low-dose cytarabine in patients 65+ with untreated acute myeloid leukemia ineligible for …
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CLINICAL_TRIALS trial_result · 2021-11-15Clinical Trial Update: Treatment of Patients With Myelodysplastic Syndrome or Acute Myelocytic Leukemia With an Impending Hematological Relapse With Azacitidine (Vidaza) [Phase 2]
Phase 2 trial investigating azacitidine (Vidaza) for patients with myelodysplastic syndrome or acute myeloid leukemia at impending hematolog…
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CLINICAL_TRIALS trial_result · 2021-11-15Clinical Trial Update: Individualized Induction Therapy for Non-elderly Acute Myeloid Leukemia Patients With Adverse Risk Features [Phase 2]
Phase 2 trial evaluating individualized induction therapy for non-elderly adults with adverse-risk acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2021-11-02Clinical Trial Update: A Study of SKLB1028 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory (R/R) AML With FLT3-Mutated [Phase 3]
A Phase 3 trial comparing SKLB1028 to salvage chemotherapy in relapsed/refractory FLT3-mutated acute myeloid leukemia is ongoing with status…
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CLINICAL_TRIALS trial_result · 2021-11-02Clinical Trial Update: A Dose Confirmation Study of Oral Clofarabine for Adult Patients Previously Treated for Myelodysplastic Syndromes (MDS) [Phase 2]
A Phase 2 dose-confirmation study of oral clofarabine in adults previously treated for myelodysplastic syndromes (MDS) has completed; result…
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CLINICAL_TRIALS trial_result · 2021-11-01Clinical Trial Update: Higher or Lower Dose Cladribine, Cytarabine, and Mitoxantrone in Treating Medically Less Fit Patients With Newly Diagnosed Acute Myeloid Leukemia or Myeloid Neoplasm [Phase 2]
Phase 2 trial evaluating higher or lower doses of cladribine, cytarabine, and mitoxantrone in medically less fit patients with newly diagnos…
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CLINICAL_TRIALS trial_result · 2021-10-29Clinical Trial Update: Dociparstat Sodium (CX-01) Combined With Standard Induction Therapy for Newly Diagnosed Acute Myeloid Leukemia [Phase 2]
A Phase 2 trial assessing dociparstat sodium (CX-01) in combination with standard induction therapy for newly diagnosed acute myeloid leukem…
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CLINICAL_TRIALS trial_result · 2021-10-29Clinical Trial Update: Haematopoietic Stem Cell Transplantation (HSCT) in Comparison to Conventional Consolidation Therapy for Patients With Acute Myeloid Leukemia (AML) (Intermediate Risk) </= 60y. After First CR [Phase 3]
A Phase 3 trial comparing hematopoietic stem cell transplantation to conventional consolidation therapy in intermediate-risk acute myeloid l…
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CLINICAL_TRIALS trial_result · 2021-10-29Clinical Trial Update: A Study to Evaluate the Tolerance and Efficacy of Mitoxantrone Hydrochloride Liposome Injection Combined With Cytarabine in Patients With Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
Early-stage study evaluating mitoxantrone hydrochloride liposome injections with cytarabine in treatment-naive or relapsed/refractory acute …
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CLINICAL_TRIALS trial_result · 2021-10-18Clinical Trial Update: Vinblastine for Leukoreduction in Newly Diagnosed AML and Hyperleukocytosis [Phase 2]
Phase 2 trial update evaluating vinblastine for leukoreduction in newly diagnosed acute myeloid leukemia with hyperleukocytosis.
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CLINICAL_TRIALS trial_result · 2021-10-15Clinical Trial Update: GLAD-AML - Glasdegib (Pf-04449913) With Two Standard Decitabine Regimens for Older Patients With Poor-risk Acute Myeloid Leukemia [Phase 2]
Phase 2 trial update for GLAD-AML using Glasdegib with two decitabine regimens in older patients with poor-risk acute myeloid leukemia; stud…
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CLINICAL_TRIALS trial_result · 2021-10-14Clinical Trial Update: HCT Versus CT in Elderly AML [Phase 3]
Phase 3 trial comparing hematopoietic cell transplantation (HCT) versus conventional therapy (CT) in elderly patients with acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2021-10-12Clinical Trial Update: CBA Versus FBA Conditioning Followed by Allogeneic HSCT in Treatment of High Risk and Refractory AML [Phase 3]
Phase 3 trial comparing CBA vs FBA conditioning followed by allogeneic HSCT in high-risk and refractory AML is underway; current status is u…