Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Clinical Study of Venetoclax Combined With CACAG Regimen in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 study evaluating venetoclax in combination with the CACAG regimen for relapsed/refractory acute myeloid leukemia is currently recrui…
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Efficacy and Safety of Lisafotoclax Plus Decitabine and Homoharringtonine in Venetoclax/Azacitidine Pretreated AML Patients [Phase 2]
Phase 2 trial evaluating lisafotoclax in combination with decitabine and omacetaxine mepesuccinate (homoharringtonine) for acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: A Study of GDX012 in Adults With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
The clinical trial update reports termination of a Phase 1/2 study of GDX012 in adults with relapsed or refractory acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Study of C6 Ceramide NanoLiposome (CNL) in Patients With Relapsed/Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 study of C6 Ceramide NanoLiposome (CNL) in relapsed/refractory acute myeloid leukemia; the trial is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML) [Phase 1]
Phase 1 clinical trial of CD123-directed T-cell therapy for acute myeloid leukemia and related hematologic diseases is currently recruiting …
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: A Study to Evaluate S227928 as a Single Agent and in Combination With Venetoclax in Patients With R/R AML, MDS/AML, or CMML [Phase 1, Phase 2]
Clinical trial update for S227928 as a single agent and in combination with Venetoclax in relapsed/refractory AML, MDS/AML, and CMML shows t…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Digital PCR of CHIP and MR for MRD Monitoring After Allo-HSCT in AML
The trial tests digital PCR methods for monitoring minimal residual disease after allogeneic hematopoietic stem cell transplantation in acut…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Efficacy and Pharmacogenomics of Cladribine Based Salvage Chemotherapy in Patients With Relapse/Refractory and Secondary Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS) [Phase 2]
A Phase 2 salvage chemotherapy trial using cladribine in relapsed/refractory and high-risk myeloid diseases (acute myeloid leukemia and myel…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: A Phase I Open-Label Dose Escalation Study of Intravenous INKmune In Patients With MDS or AML [Phase 1]
A Phase I open-label dose-escalation study of intravenous INKmune in patients with myelodysplastic syndromes or acute myeloid leukemia was t…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant [Phase 1]
Phase 1 trial of intensity-modulated total marrow irradiation with fludarabine phosphate and melphalan for relapsed hematologic cancers unde…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: A Study to Find the Highest Dose of SNDX-5613 (Revumenib) as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, and Mixed Phenotype Acute Leukemia [Phase 1]
Phase 1 study to identify the highest dose of Revumenib (SNDX-5613) after hematopoietic stem cell transplant in children with acute lymphobl…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Trial to Compare Efficacy and Safety of Chemotherapy/Quizartinib vs Chemotherapy/Placebo in Adults FMS-like Tyrosine Kinase 3 (FLT3) Wild-type Acute Myeloid Leukemia (AML) [Phase 2]
A Phase 2 trial comparing chemotherapy plus quizartinib versus chemotherapy plus placebo in adults with FLT3-wild-type acute myeloid leukemi…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1) [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Enzomenib (DSP-5336) for acute leukemias, including acute myeloid leukemia and acute lymphoblastic leu…
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: Cytarabine and Daunorubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 1]
Phase 1 clinical trial evaluating cytarabine and daunorubicin hydrochloride in adults with newly diagnosed acute myeloid leukemia; results h…
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: A Proof of Concept Pilot Study of the Addition of Venetoclax to Standard Remission Induction Chemotherapy Fludarabine or Cladrabine, Cytarabine, and Granulocyte Colony Stimulating Factor (G-CSF) (FLAG or CLAG) for Frontline Therapy of Secondary Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating adding venetoclax to FLAG/CLAG induction therapy for frontline treatment of secondary acute myeloid leukemia; the s…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Dose Escalation/ Expansion Study of CA-4948 as Monotherapy in Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS) [Phase 1, Phase 2]
A phase 1/2 dose-escalation/expansion study of CA-4948 as monotherapy in acute myeloid leukemia and myelodysplastic syndrome is currently su…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Study of NMS-03592088 in Patients With Relapsed or Refractory AML or CMML [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating NMS-03592088 in relapsed or refractory acute myeloid leukemia and chronic myelomonocytic leukemia has …
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Phase 1 Study of Shattuck Labs (SL)-172154 in Subjects With MDS or AML [Phase 1]
Phase 1 study of SL-172154 in acute myeloid leukemia and myelodysplastic syndromes was terminated. Results have been posted on 2026-03-18.
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome [Phase 1]
A Phase 1 trial evaluating total marrow and lymphoid irradiation with fludarabine and melphalan before donor stem cell transplant for high-r…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide [Phase 2]
Phase 2 trial evaluating HLA-mismatched unrelated donor hematopoietic cell transplantation with post-transplantation cyclophosphamide is act…
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: A Study of Voruciclib Alone or in Combination With Venetoclax in Subjects With B-Cell Malignancies or AML [Phase 1]
Phase 1 trial update for voruciclib alone or with venetoclax in various B-cell malignancies and acute myeloid leukemia; the study has been t…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Safety and Efficacy of Venetoclax With Escalating Doses of Omacetaxine in Patients With Acute Myeloid Leukemia Safety and Efficacy of Venetoclax With Escalating Doses of Omacetaxine in Patients With Acute Myeloid Leukemia (AML) [Phase 1]
Phase 1 study assessing the safety and preliminary efficacy of venetoclax with escalating doses of omacetaxine in patients with acute myeloi…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Natural Killer-cell Therapy for Acute Myeloid Leukemia [Phase 1, Phase 2]
The clinical trial evaluating natural killer cell therapy for adult acute myeloid leukemia (refractory or relapsed) in Phase 1/2 has been te…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: CINC424A2X01B Rollover Protocol [Phase 4]
Phase 4 rollover protocol for CINC424A2X01B is active but not recruiting, spanning Primary Myelofibrosis, Polycythemia Vera, Graft-versus-ho…
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: Evaluation of DASATINIB Monotherapy Efficacy in Acute Myeloid Leukemia Patients Refractory to VENETOCLAX-AZACITIDINE [Phase 2]
Phase 2 clinical trial evaluating dasatinib monotherapy in AML patients refractory to venetoclax-azacitidine; recruitment is ongoing.