Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-05-24Clinical Trial Update: Guadecitabine With or Without Idarubicin or Cladribine in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia [Phase 2]
A Phase 2 study evaluating guadecitabine alone or in combination with idarubicin or cladribine in older adults with previously untreated acu…
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CLINICAL_TRIALS trial_result · 2022-05-24Clinical Trial Update: Safety and Efficacy of ATIR101 as Adjunctive Treatment to Blood Stem Cell Transplantation From a Haploidentical Family Donor Compared to Post-transplant Cyclophosphamide in Patients With Blood Cancer [Phase 3]
Phase 3 trial updating safety and efficacy of ATIR101 as an adjunct to haploidentical stem cell transplantation versus post-transplant cyclo…
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CLINICAL_TRIALS trial_result · 2022-05-20Clinical Trial Update: Milademetan Plus Quizartinib Combination Study in FLT3-ITD Mutant Acute Myeloid Leukemia (AML) [Phase 1]
Phase 1 trial evaluating milademetan plus quizartinib in FLT3-ITD mutant acute myeloid leukemia has been terminated with results posted.
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CLINICAL_TRIALS trial_result · 2022-05-19Clinical Trial Update: Dual Growth Factor (rhTPO + G-CSF) and Chemotherapy Combination Regimen in Acute Myeloid Leukemia: Study Protocol for a Randomized Controlled Trial [Phase 3]
Study protocol for a randomized Phase 3 trial evaluating a dual growth factor (rhTPO + G-CSF) with chemotherapy in acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2022-05-05Clinical Trial Update: Combination of Venetoclax, Hypomethylation Agent and Low-dose Cytarabine as a Salvage Therapy for Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating a combination of venetoclax, a hypomethylating agent, and low-dose cytarabine as salvage therapy for relapsed or re…
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CLINICAL_TRIALS trial_result · 2022-05-05Clinical Trial Update: A Study of Oral Venetoclax Tablet in Combination With Subcutaneous Low-Dose Cytarabine (LDAC) Injection to Assess Adverse Events in Adult Japanese Participants With Acute Myeloid Leukemia (AML) [Phase 3]
Phase 3 trial assessing adverse events of oral venetoclax with subcutaneous low-dose cytarabine in adult Japanese AML patients; study comple…
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CLINICAL_TRIALS trial_result · 2022-04-29Clinical Trial Update: Study of Chidamide Combined With Cladribine in Refractory/Relapsed Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating chidamide in combination with cladribine for refractory/relapsed acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2022-04-25Clinical Trial Update: Evaluate the Efficacy and Safety of Rasburicase (Fasturtec®) in the Prevention and Treatment of Hyperuricemia in Pediatric Patients With Non-Hodgkin's Lymphoma and Acute Leukemia [Phase 4]
Phase 4 clinical trial evaluating rasburicase for prevention and treatment of hyperuricemia in pediatric patients with non-Hodgkin's lymphom…
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CLINICAL_TRIALS trial_result · 2022-04-12Clinical Trial Update: A Study of the Effect of Blood Stem Cell Transplant After Chemotherapy Alone in Patients With Fanconi Anemia [Phase 2]
Phase 2 trial assessing the effect of blood stem cell transplant after chemotherapy in Fanconi Anemia; study terminated with posted results.
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CLINICAL_TRIALS trial_result · 2022-04-08Clinical Trial Update: A Randomized Trial of a Combination of Nintedanib/Placebo in Combination With Induction Chemotherapy for Patients With Refractory or First Relapse Acute Myeloid Leukemia [Phase 2]
Phase 2 randomized trial evaluating nintedanib/placebo in combination with induction chemotherapy for relapsed or refractory acute myeloid l…
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CLINICAL_TRIALS trial_result · 2022-04-07Clinical Trial Update: Stem Cell Transplantation From HLA Partially-Matched Related Donors for Patients With Hematologic Malignancies [Phase 3]
Phase 3 clinical trial update on stem cell transplantation from partially HLA-m matched related donors for hematologic malignancies; trial c…
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CLINICAL_TRIALS trial_result · 2022-04-07Clinical Trial Update: First in Human Testing of Dose-escalation of SAR440234 in Patients With Acute Myeloid Leukemia, Acute Lymphoid Leukemia and Myelodysplastic Syndrome [Phase 1, Phase 2]
First-in-human dose-escalation study of SAR440234 in acute leukemia and myelodysplastic syndrome was terminated; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-03-28Clinical Trial Update: Safety and Efficiency of γδ T Cell Against Hematological Malignancies After Allo-HSCT [Phase 1, Phase 2]
This clinical trial evaluates the safety and efficacy of γδ T cell therapy after allogeneic hematopoietic stem cell transplantation in hemat…
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CLINICAL_TRIALS trial_result · 2022-03-25Clinical Trial Update: Evaluating QTc, PK, Safety of Gemtuzumab Ozogamicin (GO) in Patients With CD33+ R/R AML [Phase 4]
Phase 4 trial update evaluating QTc, pharmacokinetics, and safety of gemtuzumab ozogamicin in CD33+ relapsed/refractory acute myeloid leukem…
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CLINICAL_TRIALS trial_result · 2022-03-18Clinical Trial Update: A Study Of PF-04449913 In Japanese Patients With Select Hematologic Malignancies [Phase 1]
Phase 1 study of PF-04449913 in Japanese patients with select hematologic malignancies, including acute myeloid leukemia, has completed with…
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CLINICAL_TRIALS trial_result · 2022-03-18Clinical Trial Update: GVAX vs. Placebo for MDS/AML After Allo HSCT [Phase 2]
Phase 2 clinical trial evaluating GVAX versus placebo for myelodysplastic syndrome and acute myeloid leukemia after allogeneic stem cell tra…
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CLINICAL_TRIALS trial_result · 2022-03-18Clinical Trial Update: Single Agent Decitabine in TP53 Mutated Relapsed/Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 trial of single-agent decitabine in TP53-mutated relapsed/refractory acute myeloid leukemia was terminated with results posted.
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CLINICAL_TRIALS trial_result · 2022-03-17Clinical Trial Update: CDIAG Regimen in the Treatment of Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial update for the CDIAG regimen in relapsed or refractory acute myeloid leukemia has completed enrollment.
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CLINICAL_TRIALS trial_result · 2022-03-16Clinical Trial Update: Venetoclax and Azacitidine for the Management of Molecular Relapse/Progression in Adult NPM1-mutated Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating venetoclax with azacitidine for molecular relapse/progression in adult NPM1-mutated acute myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2022-03-15Clinical Trial Update: Azacytidine + HAG Regimen vs. Azacytidine for Elderly Patients With Newly Diagnosed Myeloid Malignancy [Phase 4]
Clinical trial comparing azacitidine plus HAG regimen versus azacitidine in elderly patients with newly diagnosed myeloid malignancies; phas…
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CLINICAL_TRIALS trial_result · 2022-03-14Clinical Trial Update: A Clinical Trial to Assess the Efficacy and Safety of the Combination of a Drug Call Quizartinib With Chemotherapy (FLAG-IDA) in Patients With Acute Myeloid Leukemia That Has Not Responded to the First Treatment or That Has Returned After the First Treatment [Phase 1, Phase 2]
A clinical trial evaluating the combination of quizartinib with FLAG-IDA chemotherapy in adults with acute myeloid leukemia that is refracto…
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CLINICAL_TRIALS trial_result · 2022-03-10Clinical Trial Update: An Efficacy and Safety Study Of Pracinostat In Combination With Azacitidine In Adults With Acute Myeloid Leukemia [Phase 3]
Phase 3 trial of pracinostat with azacitidine in adults with acute myeloid leukemia was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2022-03-02Clinical Trial Update: AML Patients Bearing FLT3 Mutations Based on Peripheral Blast Clearance [Phase 3]
Phase 3 trial update in AML patients with FLT3 mutations evaluating peripheral blast clearance.
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CLINICAL_TRIALS trial_result · 2022-02-23Clinical Trial Update: Study of Liposomal Annamycin for the Treatment of Subjects With Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
A Phase 1/2 study evaluating liposomal annamycin for acute myeloid leukemia has completed with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-02-21Clinical Trial Update: GRASPA Treatment for Patients With Acute Myeloblastic Leukemia [Phase 2]
Phase 2 trial update for GRASPA in patients with Acute Myeloid Leukemia; results have been posted.