Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-10-30Clinical Trial Update: Safety and Efficacy of Unrelated Umbilical Cord Blood Microtransplantation in Patients With AML [Phase 2]
Phase 2 trial evaluating safety and efficacy of unrelated umbilical cord blood microtransplantation in patients with acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2023-10-26Clinical Trial Update: Immunochemotherapy and AlloSCT in Patients With High Risk CD33+ AML/MDS [Phase 2]
Phase 2 clinical trial evaluating immunochemotherapy and allogeneic stem cell transplantation in high-risk CD33+ acute myeloid leukemia and …
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CLINICAL_TRIALS trial_result · 2023-10-26Clinical Trial Update: SCT Plus Immune Therapy in Average Risk AML/MDS [Phase 2]
Phase 2 clinical trial update for SCT plus immune therapy in average-risk acute myeloid leukemia and myelodysplastic syndrome has completed.
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CLINICAL_TRIALS trial_result · 2023-10-25Clinical Trial Update: A Study of APG-2575 in Combination With Azacitidine in Patients With Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
Clinical trial update for APG-2575 in combination with azacitidine in adults with acute myeloid leukemia, spanning Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2023-10-10Clinical Trial Update: Biomarkers in Predicting Treatment Response to Sirolimus and Chemotherapy in Patients With High-Risk Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating biomarkers predicting response to sirolimus plus chemotherapy in high-risk acute myeloid leukemia; trial completed.
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CLINICAL_TRIALS trial_result · 2023-10-10Clinical Trial Update: Comparison of the Efficacy and Safety of Venetoclax in Combination With 3 Days Decitabine (DEC3-VEN) vs. Venetoclax in Combination With Azacitidine (VIALE-A) in the Treatment of Elderly Patients or Unfit, New-diagnosis Acute Myeloid Leukemia Patients [Phase 3]
A Phase 3 trial comparing venetoclax plus decitabine (DEC3-VEN) versus venetoclax plus azacitidine (VIALE-A) in elderly or unfit, newly diag…
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CLINICAL_TRIALS trial_result · 2023-10-05Clinical Trial Update: Safety & Activity of Controllable PRAME-TCR Therapy in Previously Treated AML/MDS or Metastatic Uveal Melanoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating controllable PRAME-TCR therapy in patients with acute myeloid leukemia, myelodysplastic syndrome, or metastatic u…
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CLINICAL_TRIALS trial_result · 2023-10-03Clinical Trial Update: Phase I/IIa Trial to Investigate BI 6727 (Volasertib) as Monotherapy or in Combination With Cytarabine in Acute Myeloid Leukaemia [Phase 2]
Phase 2 trial of BI 6727 (volasertib) as monotherapy or with cytarabine in acute myeloid leukemia has completed with posted results.
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CLINICAL_TRIALS trial_result · 2023-09-29Clinical Trial Update: Ribavirin and Hedgehog Inhibitor With or Without Decitabine in AML [Phase 2]
Phase 2 clinical trial evaluating ribavirin and Hedgehog pathway inhibitor with or without decitabine in acute myeloid leukemia has complete…
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: CPX-351 Plus Enasidenib for Relapsed AML [Phase 2]
Phase 2 clinical trial update evaluating CPX-351 in combination with enasidenib for relapsed/refractory acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: Methods of T Cell Depletion Trial (MoTD) [Phase 2]
Phase 2 trial update for methods of T cell depletion in various hematologic malignancies is ongoing.
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CLINICAL_TRIALS trial_result · 2023-09-26Clinical Trial Update: Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical Study [Phase 1, Phase 2]
Long-term follow-up update from BP-004 study (Phase 1/Phase 2) by Bellicum Pharmaceuticals; study status TERMINATED with results posted in 2…
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CLINICAL_TRIALS trial_result · 2023-09-22Clinical Trial Update: Lymphodepletion and Anti-PD-1 Blockade to Reduce Relapse in AML Patient Not Eligible for Transplant [Phase 2]
Phase 2 clinical trial evaluating lymphodepletion plus anti-PD-1 blockade to reduce relapse in acute myeloid leukemia patients ineligible fo…
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Daratumumab in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating daratumumab in relapsed or high-risk myeloid malignancies (high-risk myelodysplastic syndrome and recurrent/refract…
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Allo HSCT Using RIC for Hematological Diseases [Phase 2]
Phase 2 trial evaluating allogeneic hematopoietic stem cell transplantation with reduced-intensity conditioning for various hematologic dise…
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CLINICAL_TRIALS trial_result · 2023-09-18Clinical Trial Update: A Study of Pevonedistat and Venetoclax Combined With Azacitidine to Treat Acute Myeloid Leukemia (AML) in Adults Unable to Receive Intensive Chemotherapy [Phase 2]
Phase 2 results for a combo of pevonedistat, venetoclax, and azacitidine in adults with acute myeloid leukemia who cannot receive intensive …
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CLINICAL_TRIALS trial_result · 2023-09-18Clinical Trial Update: Pixantrone (BBR 2778) in Patients With Refractory Acute Myelogenous Leukemia (AML) [Phase 1, Phase 2]
Phase 1/2 trial of pixantrone (BBR 2778) in refractory acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2023-09-15Clinical Trial Update: Comparison Between Two Dose Levels of Daunorubicin and Between One vs. Two Induction Cycles for Adult Patients With AML [Phase 3]
Phase 3 trial comparing two daunorubicin dose levels and one versus two induction cycles in adult acute myeloid leukemia patients has comple…
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CLINICAL_TRIALS trial_result · 2023-09-14Clinical Trial Update: A Phase II Study Evaluating the Safety and Efficacy of Subcutaneous Plerixafor [Phase 2]
Phase II trial evaluating safety and efficacy of subcutaneous plerixafor in related donors of peripheral blood stem cells for various hemato…
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CLINICAL_TRIALS trial_result · 2023-09-14Clinical Trial Update: Clofarabine Pre-conditioning Followed by Stem Cell Transplant for Non-remission AML [Phase 2]
Phase 2 trial evaluating clofarabine pre-conditioning followed by stem cell transplant in acute myeloid leukemia; study terminated with resu…
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CLINICAL_TRIALS trial_result · 2023-09-13Clinical Trial Update: Itacitinib, Tacrolimus, and Sirolimus for the Prevention of GVHD in Patients With Acute Leukemia, Myelodysplastic Syndrome, or Myelofibrosis Undergoing Reduced Intensity Conditioning Donor Stem Cell Transplantation [Phase 2]
Phase 2 study evaluating a combination of Itacitinib, Tacrolimus, and Sirolimus for prevention of graft-versus-host disease in patients with…
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CLINICAL_TRIALS trial_result · 2023-09-13Clinical Trial Update: Study Augmenting TAK-659 Action in Relapsed/Refractory AML by Addition Ofthe Proteasome Inhibitor Ixazomib [Phase 1, Phase 2]
Phase 1/2 trial investigating TAK-659 in combination with Ixazomib for relapsed/refractory acute myeloid leukemia; study status terminated w…
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CLINICAL_TRIALS trial_result · 2023-09-01Clinical Trial Update: Study of Haplo-HSCT + Rivogenlecleucel vs Haplo-HSCT + Post Transplant Cyclophosphamide in Patients With AML or MDS [Phase 2, Phase 3]
A study comparing Haplo-HSCT with Rivogenlecleucel versus Haplo-HSCT with post-transplant cyclophosphamide in AML or MDS was terminated with…
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CLINICAL_TRIALS trial_result · 2023-09-01Clinical Trial Update: Study of Emerfetamab (AMG 673) in Adults With Relapsed/Refractory Acute Myeloid Leukemia (AML) [EARLY_Phase 1]
Early-phase trial of Emerfetamab (AMG 673) in adults with relapsed/refractory acute myeloid leukemia was terminated with results posted.
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CLINICAL_TRIALS trial_result · 2023-08-09Clinical Trial Update: A Study of ARGX-110 in Combination With Azacytidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) or High Risk Myelodysplatic Syndrome (MDS) [Phase 1, Phase 2]
Phase 1/2 trial evaluating ARGX-110 with azacytidine in newly diagnosed acute myeloid leukemia or high-risk myelodysplastic syndromes has co…