Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-03-12Clinical Trial Update: Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in Children [Phase 2]
Phase 2 trial exploring selective depletion of CD45RA+ T cells from allogeneic stem cell grafts to prevent GVHD in children has completed wi…
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CLINICAL_TRIALS trial_result · 2024-03-12Clinical Trial Update: Efficacy Study of Dendritic Cell Vaccination in Patients With Acute Myeloid Leukemia in Remission [Phase 2]
Phase 2 study evaluating dendritic cell vaccination as an efficacy treatment in patients with acute myeloid leukemia in remission.
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CLINICAL_TRIALS trial_result · 2024-03-08Clinical Trial Update: Study of AMG 330 in Combination With Pembrolizumab in Adult With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 study of AMG 330 in combination with pembrolizumab in adults with relapsed or refractory acute myeloid leukemia has been terminated;…
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CLINICAL_TRIALS trial_result · 2024-03-05Clinical Trial Update: A Patient-centered Communication Tool (UR-GOAL) for Older Patients With Acute Myeloid Leukemia, Their Caregivers, and Their Oncologists [NA]
A completed clinical trial evaluating UR-GOAL, a patient-centered communication tool for older adults with Acute Myeloid Leukemia, their car…
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CLINICAL_TRIALS trial_result · 2024-02-29Clinical Trial Update: Safety and Efficacy of Venetoclax Combination With Decitabine(DEC3-VEN) in the Treatment of AML in the Adult [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating venetoclax in combination with decitabine for adult acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2024-02-29Clinical Trial Update: Rapamycin in Combination With Low-dose Aracytin in Elderly Acute Myeloid Leukemia Patients [Phase 2]
Phase 2 trial evaluating rapamycin combined with low-dose cytarabine in elderly patients with acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: Quizartinib With Azacitidine or Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 1, Phase 2]
Phase 1/2 trial evaluating quizartinib with azacitidine or cytarabine in relapsed or refractory acute myeloid leukemia and myelodysplastic s…
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: Trial for Relapsed or Refractory AML Patients Combining Cytarabine and Mitoxantrone With Venetoclax (RELAX) [Phase 1, Phase 2]
Phase 1/2 trial evaluating cytarabine and mitoxantrone with venetoclax for relapsed or refractory acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2024-02-23Clinical Trial Update: Randomized Phase III Study of Intensive Chemotherapy With or Without Dasatinib (Sprycel™) [Phase 3]
Randomized Phase III trial evaluating intensive chemotherapy with or without dasatinib (Sprycel) in acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2024-02-22Clinical Trial Update: Investigator Initiated Trial of CPX-351 for Untreated Acute Myeloid Leukemia [Phase 2]
Phase 2 investigator-initiated trial of CPX-351 in untreated acute myeloid leukemia has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-02-13Clinical Trial Update: IPA Targeted Adoptive Immunotherapy vs Adult Haplo-identical Cell Infusion During Induction of High Risk Leukemia [Phase 2]
Phase 2 trial evaluating IPA-targeted adoptive immunotherapy versus adult haplo-identical cell infusion for induction in high-risk leukemia;…
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CLINICAL_TRIALS trial_result · 2024-02-08Clinical Trial Update: Study to Assess the Safety and Efficacy of Midostaurin (PKC412) in Combination With Standard Chemotherapy During Induction and Consolidation Followed by 12 Months of Maintenance Monotherapy in Patients With Newly-diagnosed FMS-like Tyrosine 3 (FLT3) Kinase Receptor-mutated Acute Myeloid Leukemia. [Phase 3]
A Phase 3 trial evaluating midostaurin added to standard chemotherapy for newly diagnosed FLT3-mutated acute myeloid leukemia has completed …
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CLINICAL_TRIALS trial_result · 2024-02-08Clinical Trial Update: Fractionated Gemtuzumab Ozogamicin Followed by Non-engraftment Donor Leukocyte Infusions for Relapsed/Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating fractionated gemtuzumab ozogamicin followed by non-engraftment donor leukocyte infusions in relapsed/refractory acu…
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CLINICAL_TRIALS trial_result · 2024-02-02Clinical Trial Update: Gemtuzumab Ozogamicin+Cytarabine vs Idarubicin+Cytarabine in Elderly Patients With AML.Mylofrance 4 [Phase 2, Phase 3]
A clinical trial comparing gemtuzumab ozogamicin plus cytarabine versus idarubicin plus cytarabine in elderly patients with acute myeloid le…
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CLINICAL_TRIALS trial_result · 2024-02-02Clinical Trial Update: A Safety and Tolerability Study of Crenolanib in Combination With Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia Patients With FLT3 Mutations [Phase 2]
Phase 2 safety and tolerability study of crenolanib with chemotherapy in newly diagnosed AML patients with FLT3 mutations completed; results…
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CLINICAL_TRIALS trial_result · 2024-02-01Clinical Trial Update: A Study of APG-115 Alone or Combined With Azacitidine in Patients With AML, CMML, or MDS [Phase 1, Phase 2]
Clinical trial update on APG-115 alone or with azacitidine in patients with AML, CMML, or MDS across Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2024-02-01Clinical Trial Update: Clofarabine and Low Dose Total Body Irradiation as a Preparative Regimen for Stem Cell Transplant in Leukemia. [Phase 1]
Phase 1 trial of clofarabine with low-dose total body irradiation as a preparative regimen for stem cell transplant in leukemia shows comple…
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CLINICAL_TRIALS trial_result · 2024-01-31Clinical Trial Update: CMV-MVA Triplex Vaccination of Stem Cell Donors in Preventing CMV Viremia in Participants With Allogeneic Transplant [Phase 1]
Phase 1 trial evaluating the CMV-MVA Triplex vaccine given to stem cell donors to prevent cytomegalovirus viremia in recipients of allogenei…
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CLINICAL_TRIALS trial_result · 2024-01-31Clinical Trial Update: Comparison of the OSHO Protocol to a Standard Arm Protocol of the German AML Intergroup in Patients With AML>60a [Phase 3]
Phase 3 trial comparing the OSHO protocol to a standard arm in adults over 60 with acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Trial Evaluating MGTA-456 in Patients With High-Risk Malignancy [Phase 2]
Phase 2 clinical trial update for MGTA-456 in high-risk hematologic malignancies; results were posted in 2024 and the study is currently act…
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: DS-3201b for Acute Myelogenous Leukemia (AML) or Acute Lymphocytic Leukemia (ALL) [Phase 1]
Phase 1 trial update for DS-3201b in acute myeloid leukemia and acute lymphocytic leukemia has been terminated with results posted.
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Flotetuzumab in Primary Induction Failure (PIF) or Early Relapse (ER) Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
Phase 1/2 clinical trial update for flotetuzumab in primary induction failure or early relapse acute myeloid leukemia; the study is terminat…
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CLINICAL_TRIALS trial_result · 2024-01-29Clinical Trial Update: Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia [Phase 2, Phase 3]
Clinical trial update for stem cell transplant in acute myeloid leukemia is terminated with results posted.
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CLINICAL_TRIALS trial_result · 2024-01-23Clinical Trial Update: A Study of TQB3454 Tablets in Patients With Blood Tumors [Phase 1, Phase 2]
Clinical trial update for TQB3454 tablets in blood tumors (Phase 1/2) involving Acute Myeloid Leukemia and Myelodysplastic Syndromes.
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CLINICAL_TRIALS trial_result · 2024-01-19Clinical Trial Update: Impact of Remission Induction Chemotherapy Prior to Allogeneic SCT in Relapsed and Poor-response Patients With AML [Phase 3]
Phase 3 trial assessing whether remission induction chemotherapy before allogeneic stem cell transplant improves outcomes in relapsed or poo…