Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-07-10Clinical Trial Update: Haploidentical Stem Cell Transplantation Using Post-Transplant Cyclophosphamide [Phase 2]
Phase 2 haploidentical stem cell transplantation trial using post-transplant cyclophosphamide was terminated.
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CLINICAL_TRIALS trial_result · 2024-07-08Clinical Trial Update: Drug-screening in AML at Relapse for Targeted Treatment [NA]
This document reports that the clinical trial NCT05732688 evaluating drug-screening at relapse for targeted treatment in acute myeloid leuke…
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: Development and Application of a Novel Digital Array PCR for Acute Myeloid Leukemia (AML)
The document reports on the development and potential application of a novel digital array PCR assay for detecting acute myeloid leukemia an…
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: Study of ASTX727 vs IV Decitabine in Participants With MDS, CMML, and AML [Phase 3]
Phase 3 study comparing ASTX727 (cedazuridine/decitabine) versus intravenous decitabine in myelodysplastic syndromes, chronic myelomonocytic…
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CLINICAL_TRIALS trial_result · 2024-06-27Clinical Trial Update: BeFluBu vs FluBuRux Conditioning in Haploidentical HCT [Phase 2]
Phase 2 clinical trial comparing BeFluBu vs FluBuRux conditioning regimens in haploidentical stem cell transplantation is currently recruiti…
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Anti-Covid-19 Vaccine in Children With Acute Leukemia and Their Siblings [Phase 1, Phase 2]
Phase 1/2 clinical trial assessing an anti-COVID-19 vaccine in children with acute leukemia and their siblings; study completed.
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CLINICAL_TRIALS trial_result · 2024-06-25Clinical Trial Update: A Study Investigating the Safety, Tolerability and Efficacy of ASP7517 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia (AML) and Relapsed/Refractory Higher Risk Myelodysplastic Syndrome (MDS) [Phase 1, Phase 2]
The document reports the completion and posting of results for a Phase 1/2 study evaluating ASP7517 for safety, tolerability, and preliminar…
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CLINICAL_TRIALS trial_result · 2024-06-21Clinical Trial Update: Phase I/II Study of Enhanced CD33 CAR T Cells in Subjects With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
This update reports a completed Phase 1/2 trial of enhanced CD33-targeted CAR T cells in relapsed or refractory acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2024-06-20Clinical Trial Update: FLT3 Clonal Evolution in Patients With Acute Myeloid Leukemia
This document reports the completion of a clinical trial investigating FLT3 clonal evolution in patients with Acute Myeloid Leukemia. The sp…
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CLINICAL_TRIALS trial_result · 2024-06-14Clinical Trial Update: Cell Therapy for CD7 Positive Acute Myeloid Leukemia or Mixed Lineage Leukemia [NA]
This clinical trial update notes the completion of a cell therapy study targeting CD7-positive acute myeloid leukemia or mixed lineage leuke…
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CLINICAL_TRIALS trial_result · 2024-06-12Clinical Trial Update: Phase I Study of Cell Therapies for the Treatment of Patients With Relapsed or Refractory AML or High-risk MDS [Phase 1]
Phase I clinical trial update from Arcellx evaluating cell therapies for relapsed or refractory acute myeloid leukemia and high-risk myelody…
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: Pinometostat With Standard Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia and MLL Gene Rearrangement [Phase 1, Phase 2]
This clinical trial update reports results from a Phase 1/2 study of pinometostat with standard chemotherapy in newly diagnosed acute myeloi…
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: RN-Led Palliative and Supportive Care Intervention [NA]
This clinical trial update notes that a nurse-led palliative and supportive care intervention for acute myeloid leukemia has completed, with…
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CLINICAL_TRIALS trial_result · 2024-06-06Clinical Trial Update: Phase I/II Trial of S64315 Plus Azacitidine in Acute Myeloid Leukaemia [Phase 1, Phase 2]
Phase I/II evaluation of S64315 in combination with azacitidine for acute myeloid leukemia has completed, with results posted on 2024-06-06.
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Efficacy Study of Oral Sapacitabine to Treat Acute Myeloid Leukemia in Elderly Patients [Phase 2]
Phase 2 efficacy trial update for oral sapacitabine in elderly patients with acute myeloid leukemia; results were posted on 2024-06-04.
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Pevonedistat, Azacitidine (or Decitabine), and Venetoclax for the Treatment of Patients With Acute Myelogenous Leukemia [Phase 1]
Phase 1 study of pevonedistat in combination with azacitidine (or decitabine) and venetoclax for acute myeloid leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2024-06-03Clinical Trial Update: A Dose Escalation and Expansion Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7283420. [Phase 1]
An early-phase dose-escalation and expansion trial to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of RO7283420…
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CLINICAL_TRIALS trial_result · 2024-05-31Clinical Trial Update: A Safety and Efficacy Study of CC-90009 Combinations in Subjects With Acute Myeloid Leukemia [Phase 1]
A Phase 1 safety and efficacy study of CC-90009 in acute myeloid leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2024-05-30Clinical Trial Update: Daunorubicin Hydrochloride, Cytarabine and Oblimersen Sodium in Treating Patients With Previously Untreated Acute Myeloid Leukemia [Phase 3]
Phase 3 trial evaluating daunorubicin hydrochloride, cytarabine, and oblimersen sodium in previously untreated acute myeloid leukemia has co…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Azacitidine or Decitabine With Venetoclax for Acute Myeloid Leukemia With Prior Hypomethylating Agent Failure [Phase 2]
This Phase 2 trial is evaluating azacitidine or decitabine in combination with venetoclax for patients with Acute Myeloid Leukemia who previ…
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CLINICAL_TRIALS trial_result · 2024-05-28Clinical Trial Update: Evaluating in Vivo AZA Incorporation in Mononuclear Cells Following Vidaza or CC486 [Phase 2]
A Phase 2 trial completed evaluating in vivo azacitidine incorporation in mononuclear cells after Vidaza or CC-486 treatment in patients wit…
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CLINICAL_TRIALS trial_result · 2024-05-28Clinical Trial Update: Real World Use of Azacitidine and Venetoclax in Acute Myeloid Leukemia in Frontline and Relapse/Refractory
A completed real-world study evaluating the use of azacitidine in combination with venetoclax for frontline and relapse/refractory acute mye…
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CLINICAL_TRIALS trial_result · 2024-05-23Clinical Trial Update: CPX-351 Versus Immediate Stem Cell Transplantation for the Treatment of High-Grade Myeloid Cancers With Measurable Residual Disease [Phase 2]
Phase 2 trial comparing CPX-351 to immediate stem cell transplantation for high-grade myeloid cancers with measurable residual disease was t…
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CLINICAL_TRIALS trial_result · 2024-05-22Clinical Trial Update: Maintenance Low Dose 5'-Azacitidine Post T Cell Depleted Allogeneic Stem Cell Transplantation for Patients With Myelodysplastic Syndrome and Acute Myelogenous Leukemia With High Risk for Post-Transplant Relapse [Phase 2]
Phase 2 trial evaluating maintenance low-dose azacitidine after T cell–depleted allogeneic stem cell transplantation in high-risk myelodyspl…
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Safety and Pharmacokinetics of Intravenous and Oral APX001 in Patients With Acute Myeloid Leukemia (AML) and Neutropenia [Phase 1]
Phase 1 study evaluating safety, tolerability, and pharmacokinetics of intravenous and oral APX001 (fosmanogepix) in patients with Acute Mye…