Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-11-08Clinical Trial Update: Clinical Study of Venetoclax Combined with CACAG Regimen in the Treatment of Newly Diagnosed Acute Myeloid Leukemia [Phase 2]
This Phase 2 trial studied venetoclax in combination with the CACAG regimen for newly diagnosed acute myeloid leukemia. The study has comple…
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: Blockade of PD-1 in Conjunction With the Dendritic Cell/AML Vaccine Following Chemotherapy Induced Remission [Phase 2]
Phase 2 trial evaluating PD-1 blockade in combination with a dendritic cell/AML vaccine after chemotherapy-induced remission in acute myeloi…
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: A Study of the Effectiveness of Venetoclax Tablets in Adult Acute Myeloid Leukemia Participants Ineligible for Standard Induction Therapy in Russian Federation
The study evaluating venetoclax tablets in adults with acute myeloid leukemia ineligible for standard induction therapy in the Russian Feder…
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: Natural Killer(NK) Cell Therapy for Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial evaluating allogeneic natural killer cell therapy for acute myeloid leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: Dose Escalation Study to Investigate the Safety, Tolerability and Pharmacokinetics of ASP2215 in Japanese Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
This update reports the completion of a Phase 1 dose-escalation study of ASP2215 (gilteritinib) in Japanese patients with Relapsed or Refrac…
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: MargheRITA (Remote Intelligence for Therapeutic Adherence) [NA]
A completed clinical trial named MargheRITA (Remote Intelligence for Therapeutic Adherence) sponsored by Advice Pharma Group srl studied tre…
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: Natural Killer(NK) Cell Therapy for AML Minimal Residual Disease [Phase 1]
Phase 1 trial of natural killer cell therapy for acute myeloid leukemia presenting minimal residual disease has been terminated.
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: A Post-Marketing Surveillance Study to Assess the Safety of Oral Azacitidine Maintenance Therapy in Korean Patients With Acute Myeloid Leukemia
This clinical trial update describes a post-marketing safety surveillance study evaluating oral azacitidine maintenance therapy in Korean pa…
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: A Study of ASP2215 in Combination With Induction and Consolidation Chemotherapy in Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 1]
Phase 1 study evaluating ASP2215 (gilteritinib) in combination with induction and consolidation chemotherapy in newly diagnosed acute myeloi…
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CLINICAL_TRIALS trial_result · 2024-11-04Clinical Trial Update: Nivolumab and Azacitidine With or Without Ipilimumab in Treating Patients With Refractory/Relapsed or Newly Diagnosed Acute Myeloid Leukemia [Phase 2]
Phase 2 trial testing nivolumab and azacitidine with or without ipilimumab for refractory/relapsed or newly diagnosed acute myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2024-11-01Clinical Trial Update: Talazoparib and Gemtuzumab Ozogamicin for the Treatment of CD33 Positive Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 trial evaluating the combination of talazoparib and gemtuzumab ozogamicin for CD33-positive relapsed or refractory acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2024-11-01Clinical Trial Update: A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Escalating Doses of AGS67E Given as Monotherapy in Subjects With Acute Myeloid Leukemia (AML) [Phase 1]
A terminated Phase 1 study evaluating safety, tolerability, and pharmacokinetics of escalating doses of AGS67E as monotherapy in adults with…
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplantation [Phase 2]
Phase 2 clinical trial update on a Triplex CMV vaccine designed to prevent CMV infection in patients undergoing hematopoietic stem cell tran…
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Evaluation of CPX-351 Monotherapy in Acute Myeloid Leukemia Secondary to Myeloproliferative Neoplasm [Phase 2]
Phase 2 evaluation of CPX-351 monotherapy in acute myeloid leukemia secondary to myeloproliferative neoplasm has completed.
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Study Impact on Outcome of Eltrombopag in Elderly Patients with Acute Myeloid Leukemia Receiving Induction Chemotherapy [Phase 2]
Clinical trial update on eltrombopag for elderly patients with acute myeloid leukemia undergoing induction chemotherapy (Phase 2).
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CLINICAL_TRIALS trial_result · 2024-10-26Clinical Trial Update: Venetoclax and Selinexor in Treating Patients with Relapsed or Refractory High Risk Hematologic Malignancies [Phase 1]
This Phase 1 trial evaluated the combination of venetoclax and selinexor in relapsed or refractory high-risk hematologic malignancies, inclu…
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: FT538 in Combination With Daratumumab in AML Acute Myeloid Leukemia [Phase 1]
This Phase 1 trial evaluated FT538 in combination with daratumumab in acute myeloid leukemia, including monocytic leukemia, and has complete…
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: A Study to Evaluate Escalating Doses of ASP1235 (AGS62P1) Given as Monotherapy in Subjects With Acute Myeloid Leukemia (AML) [Phase 1]
A Phase 1 trial evaluating escalating doses of ASP1235 (AGS62P1) as monotherapy in subjects with acute myeloid leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2024-10-22Clinical Trial Update: Testing Nivolumab in Combination With Decitabine and Venetoclax in Patients With Newly Diagnosed TP53 Gene Mutated Acute Myeloid Leukemia [Phase 1]
Phase 1 trial evaluating nivolumab in combination with decitabine and venetoclax for newly diagnosed TP53-mutated acute myeloid leukemia; st…
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: Cytomegalovirus (CMV) Vaccine in Donors and Recipients Undergoing Allogeneic Hematopoietic Cell Transplant (HCT) [Phase 2]
Phase 2 trial of a cytomegalovirus vaccine for donors and recipients undergoing allogeneic hematopoietic cell transplantation has completed,…
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CLINICAL_TRIALS trial_result · 2024-10-17Clinical Trial Update: CD34 Selected Allogeneic HCT w/ Myeloablative Conditioning Plus CD8+ Memory TCell Infusion in MDS, AL and CML [Phase 2]
Phase 2 clinical trial evaluating CD34-selected allogeneic hematopoietic stem cell transplantation with myeloablative conditioning plus CD8+…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: A Study of ASP2215 in Combination With Induction and Consolidation Chemotherapy in Patients With Newly Diagnosed Acute Myeloid Leukemia. [Phase 1, Phase 2]
Astellas reports results from a Phase 1/2 study of ASP2215 (gilteritinib) in combination with induction and consolidation chemotherapy for n…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: Study of a New Intravenous Drug, Called S65487, in Patients With Acute Myeloid Leukemia, Non Hodgkin Lymphoma, Multiple Myeloma or Chronic Lymphocytic Leukemia [Phase 1]
Phase 1 study of the intravenous agent S65487 in relapsed or refractory hematologic cancers (acute myeloid leukemia, non-Hodgkin lymphoma, m…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Post-transplantation Benadamustine and Cyclophosphamide in Patients With Refractory Myeloid Malignancies [Phase 2]
Phase 2 trial evaluating post-transplantation bendamustine and cyclophosphamide in refractory myeloid malignancies has completed.
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: Safety, Tolerability, PK, PD, and Efficacy of AMG 427 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia [Phase 1]
This Phase 1 study of AMG 427 in relapsed/refractory acute myeloid leukemia assessed safety, tolerability, PK/PD, and preliminary efficacy; …