Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-01-14Clinical Trial Update: A Study of ASP2215 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase 3 (FLT3) Mutation [Phase 3]
Phase 3 trial comparing ASP2215 (gilteritinib) to salvage chemotherapy in relapsed or refractory acute myeloid leukemia with FLT3 mutation. …
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CLINICAL_TRIALS trial_result · 2025-01-14Clinical Trial Update: A Study of Siremadlin Alone and in Combination With Donor Lymphocyte Infusion in Acute Myeloid Leukemia Post-allogeneic Stem Cell Transplant [Phase 1, Phase 2]
Clinical trial evaluating siremadlin alone and in combination with donor lymphocyte infusion for acute myeloid leukemia after allogeneic ste…
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: Ivosidenib and Combination Chemotherapy for the Treatment of IDH1 Mutant Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 trial evaluating the addition of ivosidenib to chemotherapy for IDH1-mutant relapsed or refractory acute myeloid leukemia, including…
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CLINICAL_TRIALS trial_result · 2025-01-07Clinical Trial Update: Ipilimumab and Decitabine in Treating Patients With Relapsed or Refractory Myelodysplastic Syndrome or Acute Myeloid Leukemia [Phase 1]
Phase 1 clinical trial update on the combination of ipilimumab and decitabine in patients with relapsed or refractory myelodysplastic syndro…
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: Cord Blood Transplant With Dilanubicel for the Treatment of HIV Positive Hematologic Cancers [Phase 2]
Phase 2 trial evaluating cord blood transplant with Dilanubicel for HIV-positive hematologic cancers; the study was terminated and results w…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Safety and Efficacy of Mitoxantrone Hydrochloride Liposome Based DCMG Regimen for R/R AML [Phase 2]
Phase 2 clinical trial evaluating the safety and efficacy of a liposome-encapsulated mitoxantrone regimen for relapsed or refractory acute m…
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CLINICAL_TRIALS trial_result · 2024-12-24Clinical Trial Update: Study of FF-10101-01 in Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial evaluating FF-10101-01 in adults with relapsed or refractory acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Activity of Idasanutlin in Combination With Either Chemotherapy or Venetoclax in Treatment of Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias or Solid Tumors [Phase 1, Phase 2]
Clinical trial evaluating idasanutlin in combination with chemotherapy or venetoclax in pediatric and young adult relapsed/refractory acute …
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: A Phase Ib/II Multicenter Open-label Study of Bemcentinib (BGB324) in Patients With AML or MDS [Phase 1, Phase 2]
A Phase Ib/II multicenter open-label study of bemcentinib (BGB324) in acute myeloid leukemia or myelodysplastic syndromes has completed and …
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: A Biomarker-Directed Phase 2 Trial of Tamibarotene (SY-1425) in Participants With Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 2]
A biomarker-directed Phase 2 trial of tamibarotene (SY-1425) in acute myeloid leukemia and myelodysplastic syndrome has completed and posted…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: Efficacy of Dendritic Cell Therapy for Myeloid Leukemia and Myeloma [Phase 2]
Phase 2 trial evaluating dendritic cell therapy for acute myeloid leukemia, chronic myeloid leukemia, and multiple myeloma reports efficacy …
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: Fludarabine, Cytarabine, and Pegcrisantaspase for the Treament of Relapsed or Refractory Leukemia [Phase 1]
Phase 1 trial of fludarabine, cytarabine, and pegcrisantaspase for relapsed or refractory leukemias was terminated; the update notes the stu…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: Natural Killer Cell (CYNK-001) Infusions in Adults with AML [Phase 1]
Phase 1 trial examining CYNK-001 natural killer cell infusions in adults with acute myeloid leukemia; the study was terminated.
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CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: T-cell Receptor α/β Depleted Donor Lymphocyte Infusion [Phase 1]
Phase 1 trial of T-cell receptor α/β-depleted donor lymphocyte infusion was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Venetoclax in Combination with 5 Days Azacitidine in Untreated AML Patients, Not Eligible for Standard Induction Therapy [Phase 2]
A Phase 2 clinical trial evaluating venetoclax in combination with five days of azacitidine in untreated acute myeloid leukemia patients who…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: A Study of TAS1440 With ATRA in Subjects With r/r AML [Phase 1]
A Phase 1 study of TAS1440 in combination with all-trans retinoic acid for relapsed or refractory acute myeloid leukemia has been terminated…
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CLINICAL_TRIALS trial_result · 2024-12-06Clinical Trial Update: Flotetuzumab for Relapsed Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Following Allogeneic Hematopoietic Cell Transplantation (Allo-HCT) [Phase 2]
Phase 2 clinical trial update of flotetuzumab for relapsed acute myeloid leukemia and myelodysplastic syndrome after allogeneic stem cell tr…
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CLINICAL_TRIALS trial_result · 2024-12-06Clinical Trial Update: Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies [Phase 1]
Phase 1 clinical trial studying tagraxofusp in pediatric patients with CD123-expressing hematologic malignancies is currently recruiting, sp…
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CLINICAL_TRIALS trial_result · 2024-11-29Clinical Trial Update: Assessing Refractoriness and Infectious Survival Events in AML
A completed AML clinical trial update focusing on refractoriness and infectious survival events.
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CLINICAL_TRIALS trial_result · 2024-11-27Clinical Trial Update: A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05) [Phase 1]
Phase 1 trial of evorpacept (ALX148) in combination with venetoclax and azacitidine for adults with acute myeloid leukemia has been terminat…
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CLINICAL_TRIALS trial_result · 2024-11-22Clinical Trial Update: Induced Pluripotent Stem Cells Derived Natural Killer Cells Therapy for Refractory and Relaps Acute Myelogenous Leukemia [EARLY_Phase 1]
Early-phase clinical trial evaluating induced pluripotent stem cell-derived natural killer cells for refractory or relapsed acute myeloid le…
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CLINICAL_TRIALS trial_result · 2024-11-21Clinical Trial Update: Research Development（RD）13-02 Chimeric Antigen Receptor(CAR) -T Cell Injection for Patients With r/r Cluster Of Differentiation 7（CD7）+ T-Acute Lymphoblastic Leukemia(ALL)/T-Lymphoblastic Lymphoma(LBL) /Acute Myelogenous Leukemia(AML) [EARLY_Phase 1]
This early-phase (Phase 1) clinical trial update reports completion of a study evaluating CD7-targeted CAR-T cell therapy in patients with r…
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CLINICAL_TRIALS trial_result · 2024-11-19Clinical Trial Update: WT1 Vaccine Treatment of Patients in Remission From Acute Myeloid Leukemia (AML) or Acute Lymphoblastic Leukemia (ALL) [Phase 2]
Phase 2 trial evaluating the WT1 vaccine in patients in remission from acute myeloid leukemia or acute lymphoblastic leukemia has completed …
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CLINICAL_TRIALS trial_result · 2024-11-19Clinical Trial Update: Galinpepimut-S in Combination With Pembrolizumab in Patients With Selected Advanced Cancers [Phase 1, Phase 2]
Clinical trial update for Galinpepimut-S in combination with pembrolizumab in selected advanced cancers (Phase 1/2) with completed status an…
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: Single Agent and Combined Inhibition After Allogeneic Stem Cell Transplant [Phase 1]
Phase 1 clinical trial evaluating single-agent and combined inhibition after allogeneic stem cell transplant in patients with acute myeloid …