Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-03-07Clinical Trial Update: Myeloablative Hematopoietic Progenitor Cell Transplantation (HPCT) for Pediatric Malignancies
This completed clinical trial evaluated myeloablative hematopoietic progenitor cell transplantation in pediatric patients with chronic myelo…
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Study to Evaluate Adverse Events and Movement of Intravenously (IV) Infused ABBV-787 in Adult Participants With Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML) [Phase 1]
A Phase 1 study evaluating adverse events and intravenous ABBV-787 in adults with relapsed/refractory acute myeloid leukemia has been termin…
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: 2157GCCC:Phase 1 of Calaspargase Pegol-mknl W/ Cytarabine and Idarubicin in Newly Dx AML [Phase 1]
Phase 1 clinical trial evaluating Calaspargase Pegol-mknl in combination with cytarabine and idarubicin for newly diagnosed acute myeloid le…
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: LILRB4 STAR-T Cells in the Treatment of R/R AML/CMML [Phase 1]
A Phase 1 trial evaluating LILRB4 STAR-T Cells for relapsed/refractory acute myeloid leukemia and chronic myelomonocytic leukemia has comple…
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CLINICAL_TRIALS trial_result · 2025-03-03Clinical Trial Update: A Trial of AK117 (Anti-CD47 Antibody) in Patients With Acute Myeloid Leukemia [Phase 1, Phase 2]
AK117, an anti-CD47 antibody developed by Akeso, is being evaluated in adults with acute myeloid leukemia in a Phase 1/2 trial. The study st…
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CLINICAL_TRIALS trial_result · 2025-02-28Clinical Trial Update: Gilteritinib vs Midostaurin in FLT3 Mutated Acute Myeloid Leukemia [Phase 2]
Phase 2 randomized trial comparing gilteritinib to midostaurin in FLT3-mutated acute myeloid leukemia; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-02-26Clinical Trial Update: Study to Evaluate the Safety and Preliminary Efficacy of CLL1 and CD38 Dual CAR-T in r/r AML [EARLY_Phase 1]
Phase 1 study evaluating the safety and preliminary efficacy of CLL1 and CD38 dual CAR-T cells in relapsed/refractory acute myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2025-02-25Clinical Trial Update: Midostaurin Associated With Standard Chemotherapy in Patients With Core-binding Factor Leukemia [Phase 2]
A Phase 2 trial evaluating midostaurin with standard chemotherapy for core-binding factor acute myeloid leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: Tamibarotene Plus Venetoclax/Azacitidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) [Phase 2]
Phase 2 trial evaluating tamibarotene in combination with venetoclax and azacitidine in newly diagnosed acute myeloid leukemia has been term…
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CLINICAL_TRIALS trial_result · 2025-02-21Clinical Trial Update: APR-246 in Combination With Venetoclax and Azacitidine in TP53-Mutant Myeloid Malignancies [Phase 1]
Phase 1 study evaluating APR-246 in combination with venetoclax and azacitidine for TP53-mutant myeloid malignancies has completed and poste…
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CLINICAL_TRIALS trial_result · 2025-02-21Clinical Trial Update: IDH1/2 Mutational Analysis in AML Patients: Diagnosis and Follow-up
This update reports on a completed study examining IDH1/2 mutational analysis in patients with Acute Myeloid Leukemia to aid diagnosis and f…
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CLINICAL_TRIALS trial_result · 2025-02-20Clinical Trial Update: Acute Myeloid Leukemia Treated With With NETrin Abs in Combination With [AZACITIDINE + VENETOCLAX] [Phase 1, Phase 2]
A Phase 1/2 trial evaluating NETrin Abs in combination with azacitidine and venetoclax for refractory acute myeloid leukemia has been termin…
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: A Study of Midostaurin Efficacy and Safety in Newly Diagnosed Patients With FLT3-mutated AML [Phase 2]
A Phase 2 trial assessing the efficacy and safety of midostaurin in newly diagnosed FLT3-mutated acute myeloid leukemia has completed enroll…
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: A Telehealth Advance Care Planning Intervention for Older Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome [NA]
This clinical trial update reports results for a telehealth advance care planning intervention targeting older patients with Acute Myeloid L…
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CLINICAL_TRIALS trial_result · 2025-02-05Clinical Trial Update: Study of Magrolimab in Combination With Azacitidine Versus Physician's Choice of Venetoclax in Combination With Azacitidine or Intensive Chemotherapy in Patients With TP53 Mutant Acute Myeloid Leukemia That Have Not Been Treated [Phase 3]
Phase 3 study of magrolimab in combination with azacitidine in TP53-mutant acute myeloid leukemia was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Study of Allogeneic Double Negative T Cells (DNT-UHN-1) in Patients With High Risk Acute Myeloid Leukemia [Phase 1]
Phase 1 trial assessing allogeneic double negative T cells (DNT-UHN-1) in high-risk acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Tagraxofusp in Patients With CD123+ or With BPDCN-IPh-like Acute Myeloid Leukemia [Phase 2]
Phase 2 study of Tagraxofusp in patients with CD123+ or BPDCN-like acute myeloid leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: GITMO AML/MDS-Relapse Registry Study
The GITMO AML/MDS-Relapse Registry Study has completed.
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Phase I Study of GNKG168 in Acute Lymphoblastic Leukemia and Acute Myelogenous Leukemia [Phase 1]
This clinical trial update summarizes Phase I results for GNKG168 in relapsed acute lymphoblastic leukemia and relapsed acute myeloid leukem…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Safety and Clinical Activity of KT-253 in Adult Patients with High Grade Myeloid Malignancies, Acute Lymphocytic Leukemia, Lymphoma, Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating safety and preliminary activity of KT-253 in adults with high-grade myeloid malignancies, acute lymphoblas…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: BI 836858 Dose Escalation in Patients With Refractory or Relapsed Acute Myeloid Leukemia and in Patients With AML in Complete Remission With High Risk to Relapse [Phase 1]
Phase 1 dose-escalation trial of BI 836858 in adults with refractory or relapsed acute myeloid leukemia and in AML in complete remission wit…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Trial of LAVA-051 in Patients with Relapsed/refractory CLL, MM, or AML [Phase 1]
The Phase 1 trial of LAVA-051 in relapsed/refractory Chronic Lymphocytic Leukemia, Multiple Myeloma, or Acute Myeloid Leukemia has been term…
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer [NA]
This update reports the completion of a clinical trial evaluating health care coach support to reduce acute care use and costs in cancer pat…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: SGI-110 in Participants With Myelodysplastic Syndromes (MDS) or Acute Myelogenous Leukemia (AML) [Phase 1, Phase 2]
Clinical trial update reporting completion and posted results for SGI-110 (guadecitabine) in patients with myelodysplastic syndromes, chroni…
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CLINICAL_TRIALS trial_result · 2025-01-16Clinical Trial Update: Accelerated Dose Schedule of Cytarabine Consolidation Therapy for Older Patients With Acute Myeloid Leukemia (AML) in Complete Remission [Phase 2]
A Phase 2 study evaluating an accelerated cytarabine consolidation schedule for older patients with acute myeloid leukemia in complete remis…