Acute Myeloid Leukemia
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CLINICAL_TRIALS research · 2015-05-06Clinical Trial Update: Studying Gene Expression in Tissue Samples From Young Patients With Acute Myeloid Leukemia
The document reports on a completed study by the Children's Oncology Group investigating gene expression in tissue samples from young patien…
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CLINICAL_TRIALS research · 2015-04-30Clinical Trial Update: Development of Immunological Assays for the Evaluation of Tumor Antigen Specific Immunity
A completed clinical trial update on developing immunological assays to evaluate tumor antigen-specific immunity. The study includes ovarian…
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CLINICAL_TRIALS research · 2015-04-24Clinical Trial Update: A Study of the Efficacy and Safety of Lenalidomide Combined to Escalating Doses of Chemotherapy in Intermediate-2-or High Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) With Del 5q [Phase 2]
This is a Phase 2 clinical trial evaluating lenalidomide combined with escalating-dose chemotherapy for intermediate-2 or high-risk myelodys…
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CLINICAL_TRIALS research · 2015-03-06Clinical Trial Update: S9031-9333-0106-0112-A Study of Biomarkers in Samples From Patients With Acute Myeloid Leukemia Treated With Standard Chemotherapy With or Without Gemtuzumab Ozogamicin
A completed study evaluating biomarkers in samples from acute myeloid leukemia patients treated with standard chemotherapy with or without g…
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CLINICAL_TRIALS research · 2015-03-06Clinical Trial Update: S9333A Study of Blood and Bone Marrow Samples From Patients With Previously Untreated Primary Acute Myeloid Leukemia
This is an update on the SWOG S9333A clinical trial that collects blood and bone marrow samples from patients with previously untreated prim…
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CLINICAL_TRIALS research · 2015-01-06Clinical Trial Update: Azacytidine Plus FLAG for Relapsed or Refractory AML [Phase 2]
Phase 2 trial evaluating azacitidine plus FLAG for relapsed or refractory acute myeloid leukemia; current status is unknown.
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CLINICAL_TRIALS research · 2014-10-29Clinical Trial Update: Idarubicin at Different Dosages as Induction Therapy for Newly Diagnosed Acute Myeloid Leukaemia [Phase 4]
This document discusses an ongoing Phase 4 clinical trial evaluating different idarubicin dosing regimens as induction therapy for newly dia…
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CLINICAL_TRIALS research · 2014-06-11Clinical Trial Update: A Trial to Establish the Feasibility of Combining Either the Tyrosine Kinase Inhibitor AC220,CXCR4 Inhibitor Plerixafor or HSP90 Inhibitor Ganetespib With Chemotherapy in Older Patients With Acute Myeloid Leukaemia and High Risk Myelodysplastic Syndrome. [Phase 1, Phase 2]
This update notes the completion of a Phase 1/2 clinical trial evaluating the feasibility of combining three agents (Quizartinib, Plerixafor…
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CLINICAL_TRIALS research · 2014-05-06Clinical Trial Update: Rapid Profiling of Bone Marrow, at Presentation and After 5 Days of Induction Therapy
This clinical trial update covers rapid profiling of bone marrow at presentation and after five days of induction therapy in acute myeloid l…
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CLINICAL_TRIALS research · 2014-03-26Clinical Trial Update: Open-label Clinical Trial to Investigate the Safety and Tolerability of Allogeneic B-cell Concentrates for Immune Reconstitution After Allogeneic Stem Cell Transplantation Measured as Response to a Antedated Single Vaccination [Phase 1, Phase 2]
Open-label Phase 1/2 clinical trial evaluating the safety and tolerability of donor-derived allogeneic B-cell concentrates to support immune…
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CLINICAL_TRIALS research · 2014-02-27Clinical Trial Update: Role of the Therapy Tailored to Risk Factors in Treating Adult Patients (≤60) With Acute Myeloid Leukemia [Phase 3]
A Phase 3 clinical trial evaluating a risk-factor–tailored therapy approach for adults ≤60 with acute myeloid leukemia. The document provide…
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CLINICAL_TRIALS research · 2014-01-08Clinical Trial Update: T-cell Depleted Donor Lymphocyte Infusion (DLI)for Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome (MDS) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating T-cell depleted donor lymphocyte infusion for acute myeloid leukemia and high-risk myelodysplastic syndr…
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CLINICAL_TRIALS research · 2014-01-06Clinical Trial Update: Vaccine Therapy and GM-CSF in Treating Patients With Acute Myeloid Leukemia in Remission [Phase 3]
Phase 3 trial evaluating vaccine therapy in combination with GM-CSF for patients with acute myeloid leukemia in remission is underway. The c…
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CLINICAL_TRIALS research · 2013-12-19Clinical Trial Update: Combination Chemotherapy, Biological Therapy, and Bone Marrow Transplantation in Treating Patients With Acute Myeloid Leukemia [Phase 3]
A Phase 3 clinical trial is evaluating the combination of chemotherapy, biological therapy, and bone marrow transplantation for treating acu…
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CLINICAL_TRIALS research · 2013-12-19Clinical Trial Update: Cyclosporine and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
Clinical trial update for a Phase 2 study of cyclosporine with combination chemotherapy in relapsed or refractory acute myeloid leukemia; cu…
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CLINICAL_TRIALS research · 2013-12-11Clinical Trial Update: Phase I/II Trial: BIBF 1120 Added to Low-dose Cytarabine in Elderly Patients With Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
Phase I/II clinical trial testing BIBF 1120 (nintedanib) added to low-dose cytarabine in elderly patients with Acute Myeloid Leukemia.
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CLINICAL_TRIALS research · 2013-11-19Clinical Trial Update: Hematopoietic Stem Cell Transplantation With Targeted Busulfan and Fludarabine in Pediatric AML [Phase 2]
Phase 2 clinical trial update evaluating targeted busulfan and fludarabine in pediatric acute myeloid leukemia undergoing hematopoietic stem…
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CLINICAL_TRIALS research · 2013-11-15Clinical Trial Update: RFC and MTHFR SNPs & hENT1- dCK Expression as Prognostic Factors in ALL & hENT1- dCK Expression as Prognostic Factors in AML
This clinical trial update investigates whether RFC and MTHFR SNPs and hENT1-dCK expression serve as prognostic factors in acute lymphoblast…
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CLINICAL_TRIALS research · 2013-11-06Clinical Trial Update: Combination Chemotherapy With or Without Monoclonal Antibody Therapy in Treating Patients With Refractory or Relapsed Acute Myelogenous Leukemia [Phase 3]
Phase 3 clinical trial update evaluating chemotherapy with or without monoclonal antibody therapy in patients with refractory or relapsed ac…
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CLINICAL_TRIALS research · 2013-10-31Clinical Trial Update: Program of Evaluation and Geriatric Intervention on the Functional Status, Quality of the Life, and Survival [NA]
A clinical trial update describing a program to evaluate geriatric intervention aimed at improving functional status, quality of life, and s…
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CLINICAL_TRIALS research · 2013-07-10Clinical Trial Update: Biomarkers in Samples From Adult Patients With Acute Myeloid Leukemia Who Failed Existing Standard-of-Care Treatment
This clinical trial update reports on biomarker analysis using samples from adults with acute myeloid leukemia who failed existing standard-…
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CLINICAL_TRIALS research · 2013-02-15Clinical Trial Update: Everolimus (RAD001) in Elderly Patients With Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial update evaluating Everolimus (RAD001) in elderly patients with acute myeloid leukemia.
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CLINICAL_TRIALS research · 2013-02-07Clinical Trial Update: Conventional and Experimental Chemotherapy With Allogeneic Transplant in Young Patients With Acute Myeloid Leukaemia
This document provides an update on a clinical trial evaluating conventional and experimental chemotherapy with allogeneic transplantation i…
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CLINICAL_TRIALS research · 2013-01-11Clinical Trial Update: the Effects and Safety of Idarubicin-strengthened Pretreatment Program and Conventional Busulfan Cyclophosphamide Pretreatment Program on High-risk Acute Myeloid Leukemia Patient [Phase 3]
This clinical trial update describes a Phase 3 study comparing an idarubicin-strengthened pretreatment regimen with a conventional busulfan/…
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CLINICAL_TRIALS research · 2012-12-04Clinical Trial Update: Safety Study of Anti LewisY Chimeric Antigen Receptor in Myeloma, Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 1]
A Phase 1 safety study evaluating an anti-LewisY chimeric antigen receptor therapy in patients with multiple myeloma, acute myeloid leukemia…