Acute Myeloid Leukemia
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CLINICAL_TRIALS research · 2024-05-17Clinical Trial Update: IMPACT-AML: Randomized Pragmatic Clinical Trial for Relapsed or Refractory AML [Phase 3]
IMPACT-AML is a Phase 3 randomized pragmatic trial evaluating treatment strategies for relapsed or refractory acute myeloid leukemia and is …
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: Study Protocol: Study on Incidence and Risk Factors of Mold Infections in Children During Leukemia Treatment
This document describes a protocol for a study to determine the incidence of mold infections in children undergoing leukemia treatment and i…
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CLINICAL_TRIALS research · 2024-05-14Clinical Trial Update: Randomised Study of Oral Azacitidine vs Placebo Maintenance in AML or MDS Patients After Allo-SCT [Phase 3]
Phase 3 randomized trial evaluating oral azacitidine versus placebo as maintenance therapy after allogeneic stem cell transplantation in pat…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: A Phase I Study of Euthare-155008(ETH-155008) in AML and NHL Patients [Phase 1]
A Phase I clinical trial update for ETH-155008 (Euthare-155008) in adult patients with non-Hodgkin lymphoma and recurrent acute myeloid leuk…
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CLINICAL_TRIALS research · 2024-05-01Clinical Trial Update: Venetoclax in Addition to Sequential Conditioning With Fludarabine / Amsacrine / Ara-C (FLAMSA) + Treosulfan for Allogeneic Blood Stem Cell Transplantation in Patients With MDS, CMML or sAML [Phase 1, Phase 2]
A Phase 1/2 clinical trial assessing adding venetoclax to FLAMSA/treosulfan conditioning for allogeneic stem cell transplantation in patient…
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CLINICAL_TRIALS research · 2024-05-01Clinical Trial Update: Study of VA Combined With HAAG Regimen in Newly Diagnosed Intermediate and High-risk AML Patients [Phase 2]
This update describes a Phase 2 clinical trial evaluating the combination of VA with the HAAG regimen in adults with newly diagnosed interme…
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CLINICAL_TRIALS research · 2024-04-29Clinical Trial Update: A Study of AK117 in Combination With Azactidine Plus Venetoclax in Patients With Acute Myeloid Leukemia [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating AK117 in combination with azacitidine and venetoclax in acute myeloid leukemia. The study is not yet rec…
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CLINICAL_TRIALS research · 2024-04-29Clinical Trial Update: Role of Antifungal Prophylaxis in Elderly Patients With Acute Myeloid Leukemia During Consolidation Therapy
A clinical trial conducted by University of Rome Tor Vergata is evaluating antifungal prophylaxis to prevent invasive aspergillosis in elder…
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CLINICAL_TRIALS research · 2024-04-26Clinical Trial Update: Efficacy and Safety of MTBF Conditioning Regimen for Salvageable Allo-HSCT in the Treatment of R/R AML [NA]
This document reports on a clinical trial evaluating the MTBF conditioning regimen for salvageable allogeneic hematopoietic stem cell transp…
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CLINICAL_TRIALS research · 2022-07-12Clinical Trial Update: Safety Study of Gene Modified Donor T-cells Following Partially Mismatched Stem Cell Transplant [Phase 1, Phase 2]
A Phase 1/2 safety study evaluating gene-modified donor T-cells after partially mismatched stem cell transplantation in patients with leukem…
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CLINICAL_TRIALS research · 2020-11-23Clinical Trial Update: GVHD Prophylaxis With Post-transplantation Bendamustine in Refractory Leukemia [Phase 1, Phase 2]
Clinical trial exploring bendamustine as GVHD prophylaxis after transplantation in refractory leukemia, reported in Phase 1/Phase 2.
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CLINICAL_TRIALS research · 2019-09-06Clinical Trial Update: Electrophysiological Biomarkers of Chemotherapy-related Cognitive Impairment and Recovery
Clinical trial assessing electrophysiological biomarkers of chemotherapy-related cognitive impairment and recovery; study completed with pos…
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CLINICAL_TRIALS research · 2018-09-07Clinical Trial Update: WT1 Immunity Via DNA Fusion Gene Vaccination in Haematological Malignancies by Intramuscular Injection Followed by Intramuscular Electroporation [Phase 2]
Phase 2 clinical trial investigating WT1 DNA fusion gene vaccination with intramuscular injection and electroporation for haematological mal…
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CLINICAL_TRIALS research · 2018-07-18Clinical Trial Update: Chidamide Plus PTCy/Cyclosporine to Prevent GVHD After Myeloablative Conditioning, Matched PBSCT [Phase 2]
Phase 2 clinical trial evaluating chidamide plus post-transplant cyclophosphamide and cyclosporine to prevent graft-versus-host disease afte…
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CLINICAL_TRIALS research · 2018-07-12Clinical Trial Update: NGS in AML Relapse
This entry provides an update on a clinical trial investigating the use of next-generation sequencing in relapsed acute myeloid leukemia at …
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CLINICAL_TRIALS research · 2018-07-02Clinical Trial Update: Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Cancer [NA]
Clinical trial update on caregiver-delivered massage therapy to improve quality of life in pediatric cancer patients; the study (NCT01053494…
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CLINICAL_TRIALS research · 2018-07-02Clinical Trial Update: Investigating the Prevalence and Prognostic Importance of Polypharmacy in Adults Treated for Newly Diagnosed Acute Myelogenous Leukemia (AML)
This clinical trial update summarizes a completed study examining the prevalence of polypharmacy in adults with newly diagnosed acute myeloi…
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CLINICAL_TRIALS research · 2018-06-14Clinical Trial Update: CART-123 FOR Relapsed/Refractory Acute Myelocytic Leukemia（AML） [Phase 1, Phase 2]
Clinical trial update for CART-123 in relapsed/refractory acute myeloid leukemia, spanning Phase 1 and Phase 2. Current status of the trial …
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CLINICAL_TRIALS research · 2018-04-20Clinical Trial Update: Screening of IDH1 and IDH2 Gene Mutations in Adult Acute Myeloid Leukemia for Possible Targeted Therapy
This Clinical Trial Update reports on screening adult AML patients for IDH1 and IDH2 mutations to identify candidates for targeted therapy.
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CLINICAL_TRIALS research · 2018-04-09Clinical Trial Update: Maintenance Therapy With Histamine Dihydrochloride and Interleukin-2 in Adult Acute Myeloid Leukemia (AML) Patients With Measurable Minimal Residual Disease (MRD)- a Non-interventional Study (NIS)
The document reports a terminated non-interventional study evaluating maintenance therapy with histamine dihydrochloride and interleukin-2 i…
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CLINICAL_TRIALS research · 2018-03-20Clinical Trial Update: Phase I/II Study With Oral Panobinostat Maintenance Therapy Following Allogeneic Stem Cell Transplantation in Patients With High Risk Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
This is a Phase I/II clinical trial evaluating oral panobinostat as maintenance therapy after allogeneic stem cell transplantation in patien…
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CLINICAL_TRIALS research · 2017-12-08Clinical Trial Update: Hematopoietic Stem Cell Microtransplantation for in AML [NA]
This entry reports on a clinical trial evaluating hematopoietic stem cell microtransplantation for acute myeloid leukemia. The study status …
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CLINICAL_TRIALS research · 2017-12-06Clinical Trial Update: Antiminor Histocompatibility Complex (MiHA) T Cells for Patients With Relapsed Hematologic Malignancies Following Matched HSCT (Guided Lymphocyte Immunopeptide Derived Expansion) [Phase 1, Phase 2]
Phase 1/2 study investigating Antiminor Histocompatibility Complex (MiHA) T cells in patients with relapsed hematologic malignancies after m…
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CLINICAL_TRIALS research · 2017-11-29Clinical Trial Update: DLAAG in the Treatment of Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome With Blast Excess [Phase 2]
A Phase 2 clinical trial evaluating DLAAG for acute myeloid leukemia and myelodysplastic syndrome with blast excess, with status currently u…
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CLINICAL_TRIALS research · 2017-11-20Clinical Trial Update: Observational Study of Patients Older Than 60 Years With Acute Myeloblastic Leukemia
This is an observational study focusing on patients older than 60 with acute myeloid leukemia. The current study status is UNKNOWN.