Acute Myeloid Leukemia
📧 Sign up to get email alerts when something new happens for Acute Myeloid Leukemia.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2024-08-01Clinical Trial Update: Sorafenib Relapase Prophylaxis After HCT With PTBCy Regimen [Phase 2]
Phase 2 clinical trial evaluating sorafenib as relapse prophylaxis after hematopoietic cell transplantation using the PTBCy regimen; the stu…
-
CLINICAL_TRIALS research · 2024-08-01Clinical Trial Update: Phase IIa Study to Assess Safety and Efficacy in the Relapsed/Refractory Acute Myeloid Leukemia [Phase 2]
Phase IIa study sponsored by Changzhou Qianhong Bio-pharma Co., Ltd. evaluating safety and efficacy in relapsed/refractory acute myeloid leu…
-
CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Vitamin A and D Supplementation in Allogeneic HCT [Phase 2]
Phase 2 clinical trial in allogeneic hematopoietic cell transplantation is evaluating vitamin A and vitamin D supplementation, currently rec…
-
CLINICAL_TRIALS research · 2024-07-29Clinical Trial Update: Study of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+) [Phase 1]
Phase 1 clinical trial evaluating the combination of iadademstat and gilteritinib in patients with relapsed/refractory acute myeloid leukemi…
-
CLINICAL_TRIALS research · 2024-07-22Clinical Trial Update: Intensive Conditioning withTHI/Bu/Flu/Ara-C in Allo-HSCT for Myeloid Malignancies With Extramedullary Involvement
This clinical trial is testing an intensive conditioning regimen consisting of Thiotepa, Busulfan, Fludarabine, and Cytarabine followed by a…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2024-07-22Clinical Trial Update: ELN 2022 in MENAFC ( Middle Eastern or North Coast of Africa ) Patients With Newly AML
ClinicalTrials.gov entry describing a trial of the ELN 2022 risk-stratification approach in patients with newly diagnosed acute myeloid leuk…
-
CLINICAL_TRIALS research · 2024-07-11Clinical Trial Update: Phase II Study of Sonrotoclax Combined With Chemotherapy in the Treatment of Newly Diagnosed Acute Myeloid Leukemia [Phase 2]
This document provides an update on a Phase II clinical trial evaluating Sonrotoclax in combination with chemotherapy for newly diagnosed ac…
-
CLINICAL_TRIALS research · 2024-07-10Clinical Trial Update: Incidence of Neutropenic Enterocolitis Study in Acute Myeloid Leukemia Patients During Intensive Therapy
A clinical trial (NCT03450512) is investigating the incidence of neutropenic enterocolitis in patients with acute myeloid leukemia undergoin…
-
CLINICAL_TRIALS research · 2024-07-10Clinical Trial Update: Study of NEROFE, a Novel Hormone-Peptide in Adult Patients With Advanced MDS and AML [Phase 1]
Phase 1 clinical trial update for NEROFE, a novel hormone-peptide, in adults with advanced myelodysplastic syndrome and acute myeloid leukem…
-
CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia (AML) Following Initial Treatment [Phase 2]
Phase 2 clinical trial investigating a combination therapy for persistent low-level acute myeloid leukemia after initial treatment. The stud…
-
CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: IL-6: A Marker for AML Chemo Sensitivity
A clinical study is evaluating whether interleukin-6 levels can predict chemotherapy response in adults with acute myeloid leukemia; the tri…
-
CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: Individualized Treatment of Pediatric R/R AML Based on Transcriptomic Profile and in Vitro Drug Sensitivity Test [NA]
This clinical trial aims to personalize treatment for children with relapsed/refractory acute myeloid leukemia using transcriptomic profilin…
-
CLINICAL_TRIALS research · 2024-07-01Clinical Trial Update: DCs Vaccine Combined With Cytokine-induced Killer Cells in Patients With AML [Phase 1, Phase 2]
Phase 1/2 clinical trial updating recruitment for a combination therapy using dendritic cell vaccine and cytokine-induced killer cells in pa…
-
CLINICAL_TRIALS research · 2024-06-27Clinical Trial Update: Venetoclax + Cytarabine Versus Idarubicin + Cytarabine : Efficacity Assessment as Post-remission Therapy to Elderly Patients With Acute Myeloid Leukemia in First Remission [Phase 2]
Phase 2 clinical trial evaluating venetoclax plus cytarabine as post-remission therapy versus idarubicin plus cytarabine in elderly patients…
-
CLINICAL_TRIALS research · 2024-06-26Clinical Trial Update: Acute Myeloid Leukemia At Initial Diagnosis and/or Relapse in Children, Teenagers and Young Adults: Molecular Profiling, Multidrug Testing and MSC Interaction Studies
Clinical trial investigating Acute Myeloid Leukemia at initial diagnosis or relapse in children, teenagers and young adults, with focus on m…
-
CLINICAL_TRIALS research · 2024-06-21Clinical Trial Update: Relationship Between Serum N/OFQ and Acute Myeloid Cell Leukemia
Clinical trial investigating the relationship between serum N/OFQ and acute myeloid leukemia; the study is currently not yet recruiting.
-
CLINICAL_TRIALS research · 2024-06-17Clinical Trial Update: ACHIEVE2 - Safety and Preliminary Efficacy of Intravenous TCB008 in Patients With Relapse or Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)/AML [Phase 1]
Clinical trial update for ACHIEVE2 reports safety and preliminary efficacy data for intravenous TCB008 in patients with relapse or refractor…
-
CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant [Phase 1, Phase 2]
This clinical trial update examines using CD34+ malignant stem cell selection for patients receiving allogeneic stem cell transplants in Pha…
-
CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: A Trial to Evaluate the Safety and Efficacy of NCR300 in Preventing Recurrence of Acute Myeloid Leukemia（AML) After Transplantation [Phase 1]
A Phase 1 trial update evaluating the safety and efficacy of NCR300 to prevent recurrence of acute myeloid leukemia after transplantation; t…
-
CLINICAL_TRIALS research · 2024-05-30Clinical Trial Update: Mitoxantrone Hydrochloride Liposome Injection, Cytarabine Combined With Venetoclax in the Treatment of R/R AML [Phase 2]
A Phase 2 clinical trial is evaluating a combination of mitoxantrone hydrochloride liposome injection, cytarabine, and venetoclax for relaps…
-
CLINICAL_TRIALS research · 2024-05-29Clinical Trial Update: Dynamics of Resistance Emergence to Azacitidine-based Therapies in Acute Myeloid Leukemia
This clinical trial investigates how resistance to azacitidine-based therapies emerges in acute myeloid leukemia and is currently recruiting…
-
CLINICAL_TRIALS research · 2024-05-29Clinical Trial Update: Sulfasalazine in AML Treated by Intensive Chemotherapy: Elderly Patients-first Line Treatment [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial is evaluating sulfasalazine added to intensive chemotherapy as first-line treatment for elderly patients wi…
-
CLINICAL_TRIALS research · 2024-05-29Clinical Trial Update: Single-cell Dynamic Profiling in Adults With Newly Diagnosed Acute Myeloid Leukemia Treated With Intensive Chemotherapy. A THEMA Study"
The THEMA study is evaluating single-cell dynamic profiling in adults with newly diagnosed acute myeloid leukemia treated with intensive che…
-
CLINICAL_TRIALS research · 2024-05-29Clinical Trial Update: The Patient Cohort of the National Center for Precision Medicine in Leukemia
This clinical trial update describes the patient cohort for the National Center for Precision Medicine in Leukemia and notes that patient re…
-
CLINICAL_TRIALS research · 2024-05-28Clinical Trial Update: A Trial to Evaluate Two Schedules of MS275 in Combination With 5AC in Elderly Patients With Acute Myeloid Leukemia (AML) [Phase 2]
Phase 2 trial evaluating two schedules of entinostat (MS275) in combination with azacitidine (5-AC) in elderly patients with acute myeloid l…